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After eating evening primrose oil and grape seed capsules, I felt uncomfortable peeing the next day.
1. gla(γ- linolenic acid) with anti-inflammatory effect will generate an endogenous substance-prostaglandin e 1 through physiological and biochemical reactions in human body. Prostaglandin e 1(pge 1) can replace the physiological function of pge2 normally produced in vivo. However, pge 1 has a strong smooth muscle relaxation effect. Therefore, although many general dose clinical experiments cannot support this statement, allergic dermatitis caused by prostaglandin has been proved to be effective against endogenous inflammatory factors (P. Edben et al., Study on evening primrose seed oil in atopic dermatitis, prostaglandin leukocyte essence fatty acid 35(2): 69-72 feb. 1989). A group of Swiss biochemists headed by biagi studied a group of children with atopic dermatitis caused by immune insufficiency with abnormal ige immunoglobulin value, and treated them with evening primrose oil. The results show that gla can effectively increase the concentration of dihomoγ linolenic acid (DGLA), an anti-inflammatory precursor in vivo, and ingest evening primrose at a high concentration. Through a series of clinical trials, it has been proved that evening primrose oil can relieve inflammation, and biochemists began to try to apply evening primrose oil to inflammatory symptoms caused by autoimmune reactions such as multiple spondylitis and lupus erythematosus, and the results were also satisfactory (P.C. Calder, The effect of fat acids on lymphfunctions, Braz j med bioltes,1993; 9(26): 90 1-9 17)。 However, it is worth noting that deep-sea fish oil (w-3 oleic acid) also has this effect. Therefore, unless you are a vegetarian, you may wish to combine grass oil with deep-sea fish oil to relieve autoimmune inflammation.

Second, relieve premenstrual syndrome When we find that the usually lively, lovely and gentle female companion suddenly becomes depressed and grumpy, the most intuitive guess of ordinary people may be "Ah! She must be the one who came. " Most women spend almost half their lives with "good friends" for five to ten days every month. However, because the female body starts about two to three days before menstruation, the prostaglandin concentration in the body will increase due to hormonal changes, and the endometrium will fall off and bleed during menstrual cramps. gla contained in evening primrose oil can inhibit the increase of prostaglandin concentration that causes inflammation. There was once a clinical experiment in which evening primrose oil was used as a drug to treat severe breast pain caused by premenstrual syndrome. The results showed that the effect of evening primrose oil was similar to that of traditional oral hormone preparation in treating breast pain (P.M. genolet et al., Diagnosis and treatment of breast pain, Red Med Sruisse Romande,1995; 1 15(5): 385-390)。 Another problem faced by women is osteoporosis, so how to reduce the loss of calcium has become an important topic. According to the experiment on mice, it was found that the urine calcium content of a group of mice fed with evening primrose oil was obviously lower, and it was more meaningful for hypercalcemia mice to prevent calcium loss (i.tulloch et al., Evening primrose oil reduced urine calcium excretion of normal and hypercalcemia rats, 1994 22(4) 227-230). This experiment also supports that taking evening primrose oil can reduce calcium loss and prevent osteoporosis. Because there are many kinds of evening primrose oil, which is helpful to women's physiological health care, evening primrose oil should be the first choice for female friends in the health food market.

Third, it can reduce the incidence of thrombosis. Evening primrose oil, like deep-sea fish oil, is an extremely polyunsaturated essential fatty acid, which will replace the inflammatory endogenous factors produced by arachidonic acid during metabolism in the body, such as prostaglandin, leukotriene and coagulation that causes coagulation reaction. Therefore, evening primrose oil not only has anti-inflammatory effect, but also has the effects of reducing coagulation reaction and preventing thrombosis (e.j. steven et al., release of prostacyclin in experimental diabetes: the effect of evening primrose oil, prostaglandin leukocyte essence fatty acid,1993 sep; 49(3): 699-70 1)。

In addition, biochemist Van Kloc-0/995 published an article in the Journal of Arterial Biomedicine, pointing out that gla can reduce the proliferation of giant cells and smooth muscle cells, and at the same time reduce the incidence of arteriosclerosis.

Evening primrose oil not only has preventive and therapeutic effects on common cardiovascular diseases of the elderly, but also is very useful for diabetes, another disease of the elderly. Neuroatrophy is a common side effect of diabetic patients. Scientists have also found that evening primrose oil can protect nerve cells and reduce the incidence of neuropathy (N.E. Cameron et al., Br.J. Pharmacol,1993; 109(4) 972-979; C.d. dines et al., European Journal of Pharmacology,1995 aug; 28 1(3): 303-309)。 Grant, a British biochemist, fed a group of pregnant diabetic mice with evening primrose oil, and found that compared with mice without evening primrose oil, the weight and health status of the mice born were normal. They also found that evening primrose oil can reduce the incidence of diabetes. Although this is not an experiment aimed at people, it is actually a good choice to use evening primrose oil as a chronic disease maintenance!

Fourthly, when cancer is mentioned in the study of anti-cancer effect, most people may classify it as a big killer to end human life, and treatment afterwards is always less meaningful than prevention beforehand. Therefore, no matter what kind of health food, most of them will "find a way" and "fight cancer". In fact, the anticancer effect of evening primrose oil only stays in the research stage with mice as samples. The anti-cancer principle is that evening primrose oil can "reduce" the lipid peroxidation of mouse adipocytes, because peroxidation will produce free radicals, denature cells and cause cancer lesions (S. Kokura et al., the efficiency of hyperthermia and heterogeneous fatty acids on experimental cancer; Cancer research,1997 jun; 57( 1 1):2200-2202)。

Therefore, evening primrose oil is considered to have anti-tumor effect. In addition, scientists also found that gla can hinder the fusion reaction between normal vascular cells and tumor endothelial cells, thus slowing down the development of tumor lesions (w.g. jiang et al., gla regulates gap junction communication of endothelial cells and its interaction with tumor cells. , prostaglandin leukocyte essential fatty acid,1997 apr; 56(4): 307-3 16)。