Medicament refers to a tablet preparation that adheres to the skin and can produce systemic or local effects. The preparation has a backing layer, a drug depot with or without a controlled release film, an adhesive layer and a protective layer to be removed before use. The patch can be applied to the whole skin surface, or to the diseased or incomplete skin surface. Among them, the patch used to complete the skin surface and deliver drugs to the blood circulation system through the skin is called transdermal patch.
1, transdermal patch works through diffusion. Drugs diffuse from the repository and directly enter the skin and blood circulation. If there is a controlled release film layer and an adhesive layer, it will enter the skin and blood circulation through the above two layers. The action time of transdermal patch is determined by its drug content and drug release rate.
2. The covering layer of transdermal patch is impermeable to active ingredients, usually impermeable to water.
3. The reservoir of transdermal patch can be skeleton type or controlled release film type.
4. The protective layer plays the role of anti-sticking and protecting the preparation, generally it is anti-sticking paper, plastic or metal material. When it is removed, it should not cause peeling of the storage and adhesive layers.
When applied to a dry, clean and intact skin surface, the patch can be firmly attached to the skin surface by gently pressing with hands or fingers, and it should not damage the skin or cause the preparation to peel off from the backing layer when removed from the skin surface. The patch has no irritation or allergy to the skin after repeated use.
There are many kinds of equipment;
Examples; R&D base of Labtech company in Germany, production technology of transdermal preparation production equipment of HH company and JORNSON &; Johnson & Johnson transdermal preparation production line
Production situation; The prospect in the international market is very objective and has great potential; It is widely used in medical disciplines.