Shensongyangxin Capsule consists of Ginseng Radix, Radix Ophiopogonis, Corni Fructus, Saviae Miltiorrhizae Radix, Semen Ziziphi Spinosae (parched), Herba Taxilli, Radix Paeoniae Rubra, Eupolyphaga Seu Steleophaga, Gan Song, Coptidis Rhizoma, Fructus Schisandrae Chinensis and Os Draconis. Has the effects of invigorating qi, nourishing yin, promoting blood circulation, dredging collaterals, clearing away heart fire and calming nerves. It is mainly used to treat ventricular premature beats and heart collateral stasis syndrome of coronary heart disease with deficiency of both qi and yin. The patients showed shortness of breath, palpitation, chest pain, increased exercise, insomnia, dreaminess, night sweats, mental fatigue and laziness.
Shen Song Yangxin Capsule can obviously improve clinical symptoms such as palpitation, chest tightness and chest pain, and reduce the frequency of atrial fibrillation. Clinical trials show that the curative effect of Shen Song Yangxin Capsule combined with western medicine is better than that of conventional western medicine, and the side effects are reduced. Shen Song Yangxin Capsule can also reduce ventricular premature beats (premature beats), reduce the number of ventricular premature beats, and improve the corresponding clinical symptoms. Shen Song Yangxin Capsule combined with metoprolol or bisoprolol or amiodarone has better therapeutic effect than western medicine alone.
Preclinical pharmacological research shows that Shen Song Yangxin Capsule can reduce the incidence of arrhythmia in experimental mice, shorten the duration of arrhythmia, reduce the degree of arrhythmia, reduce the contents of serum creatine kinase, low density lipoprotein and malondialdehyde, increase serum superoxide dismutase and myocardial tissue Na+-K+-ATPase, reduce blood pressure, coronary artery resistance and myocardial oxygen consumption, and shorten the length and weight of thrombus in vitro in rats.
Wenxin Granule consists of Radix Codonopsis, Rhizoma Polygonati, Radix Notoginseng, Amber and Gan Song. Has the effects of invigorating qi, nourishing yin, promoting blood circulation and removing blood stasis. It can also be used for shortness of breath, asthenia, palpitation, chest distress, chest pain, ventricular premature beats and atrial premature beats caused by deficiency of both qi and yin and heart pulse stasis.
Combined with Wenxin Granule on the basis of routine treatment of western medicine, it can obviously improve the clinical symptoms of patients such as palpitation, chest tightness and upset, and the treatment effect is obviously better than that of routine treatment of western medicine alone, and the side effects of drugs are few. Animal experiments show that Wenxin granule has a good regulating effect on arrhythmia, can enhance myocardial contractility and improve microcirculation.
Wenxin granule combined with metoprolol in the treatment of coronary heart disease complicated with ventricular premature beats is superior to metoprolol alone in improving dynamic electrocardiogram, which can further reduce the number of ventricular premature beats and significantly reduce side effects. Further reduce the amplitude of ST segment depression and shorten the duration of ST segment depression.
As can be seen from the above, both Shen Song Yangxin Capsule and Wenxin Granule have the effects of benefiting qi and nourishing yin, promoting blood circulation to remove blood stasis and dredging collaterals, and are suitable for patients with deficiency of both qi and yin and internal heat due to yin deficiency, mainly including coronary heart disease complicated with atrial fibrillation and ventricular premature beats. The only difference is that Shen Song Yangxin Capsule also has the function of clearing away the heart and calming the nerves. In addition, Shen Song Yangxin Capsule is also suitable for patients with coronary heart disease complicated with bradyarrhythmia (bradycardia), which has the functions of increasing heart rate and improving heart rate variability.