Point, obviously beyond the scope of acceptance of ordinary people at present. There is a scientific basis for merchants to take "collecting probiotics from the intestines of centenarians" as their promotional selling point, and this basis is intestinal flora.
There are about 1000 kinds of bacteria in the intestines of normal people, and the number of bacteria is equivalent to that of human cells. After a long period of evolution, they are related to
Humans have reached * * *, which is what we usually call the state of intestinal flora. ?
Intestinal flora is closely related to human health. The ecological balance of intestinal flora is the premise of intestinal health. Once the flora is out of balance, intestinal diseases will follow.
In a scientific study, scientists found that the intestinal flora of thin people was transplanted into the intestines of fat people, which is also true.
Why do some people promote the reason to eat probiotics to lose weight?
There is a thing called the brain-gut axis, that is, the intestinal flora is closely related to the brain. According to scientific research, mental mind
Both somatic diseases and cranial nerve lesions are related to intestinal flora imbalance. Intestinal flora is not only a good helper for scientific research, but also has been put into practice as a treatment for fecal bacteria transplantation.
First of all, in addition to the conventional gastrointestinal diseases, it even has methods to treat tumors, taking COVID-19 as an example. The intestinal flora is so extraordinary that it is not difficult for merchants to collect probiotics from the intestines of centenarians as a sales promotion point. The main sample of intestinal flora is feces. Collecting from the intestines of centenarians means collecting from the feces of centenarians.
Taking fecal bacteria transplantation as an example, the treatment process is roughly as follows.
Add fresh incense into normal saline, stir well, centrifuge, remove supernatant, and then add normal saline to resuspend.
Repeat three times. For some hard "incense", because it will leave a lot of macromolecular substances and physical residues, it can not be cleaned at one time, and
Need secondary processing.
This is not a question of advertising language. In fact, the most obvious factor is that the intestinal flora of long-lived elderly people can make people live longer.
Really?
No one dares to draw this conclusion.
Moreover, the composition of our intestinal flora is not static. With the increase of age, the human intestinal flora changes.
Yes
Take the common Bifidobacterium as an example.
In the infant stage, Bifidobacterium is the advantage of intestinal flora. We usually say that the intestinal flora of natural delivery babies is better than that of caesarean section babies.
Healthier, in fact, the core difference here is the number of bifidobacteria. From birth to 3 days, the baby's double intestines are delivered through the vagina.
Bifidobacterium is much richer than the baby born by caesarean section. ?
Second, in the next stage, Bifidobacterium longum, Bifidobacterium brevis and Bifidobacterium bifidum will appear in the baby's intestine.
Type. In the adult stage, this component has changed again, and the content of Bifidobacterium adolescentis and Bifidobacterium catenae is higher in adults. meanwhile
We observed that Bifidobacterium bifidum and Bifidobacterium brevis decreased with age, while Bifidobacterium adolescentis increased with age.
But it's rising.
Finally, talk about the elderly, especially centenarians.
The number of bifidobacteria decreases with the increase of age, and the species diversity also decreases. ?
The composition of Bifidobacterium in centenarians in China is similar to that in Europeans, but the abundance of Bifidobacterium in centenarians in China is higher. In Italy
In the intestines of centenarians, the largest number of bifidobacteria is Bifidobacterium longum, followed by Bifidobacterium adolescentis and Bifidobacterium bifidum, and then
Bifidobacterium dentatum is dominant in the intestines of centenarians in China.
In addition, Bifidobacterium gallisepticum, Bifidobacterium parvum and Bifidobacterium mollis iron can be detected in the intestines of centenarians in China.
It can be seen from Bifidobacterium that age is directly related to the composition of intestinal flora. You said that young people must make up.
Is it a little hard for centenarians to eat probiotics? It is reasonable to say that we should make up for the young people, right?
Third, look, collecting probiotics from the intestines of centenarians is not a straightforward slogan at all. The big probability is the operation of the company.
When writing a copy, I didn't really understand the specific process of R&D and manufacturing. In fact, similar problems often occur in our company.
Even if there is proofreading, there are still problems often found after batch print.
In fact, it is highly probable that the first generation of this probiotic strain was obtained from the intestines of centenarians. It's normal. Every time we
There are a large number of microorganisms in individuals, especially in the intestines, and the flora is particularly rich. ?
There is a theory that why the physical resistance of babies born naturally is relatively stronger than that of babies born by cesarean section is because in the process of natural delivery, babies
I first obtained microbial flora (mostly beneficial bacteria or colonization bacteria) from my mother's birth canal, and established the first layer of my life.
Protection mechanism.
So back to the probiotics in the topic, it is actually very easy to understand. Since it is an industrialized product, it is naturally mass-produced, so it depends on this.
A little bit, you can know that if you really collect these probiotics first, it is estimated that the sales volume will crush centenarians all over the world in a few days.
Just doing it is not enough.
Four, on a key point, I think it is necessary to mention to you that the strains found in the intestines of centenarians are unexpected.
Taste it has the effect of prolonging life. This is a relationship, not a causal relationship. As for the efficacy of this strain, as far as experiments are concerned.
The evidence has not yet been found.
Irrelevant words, does this strain like colonizing the elderly, or is it because the existence of this strain can promote?
How long people live is hard to say now. Moreover, the regulation of flora is often the whole microecology, involving thousands of microorganisms.
Things, a single strain alone, may not have worked, but they were killed by microorganisms in our own bodies.
Probiotics have a big problem. You can't eat too much stomach acid.
Common probiotic powders are coated probiotics, which can also carry gastric acid and eventually colonize the intestine; Or enteric dissolution of probiotics.
Capsule, coated with probiotic freeze-dried powder, slowly released into the intestine to reduce gastric acid and kill probiotics.
However, yogurt can't be coated and put into enteric-coated capsules. How to enter the intestine is a problem.
But some strains are relatively acid-resistant. Here, we put 16 strain in artificial gastric juice with pH=3.0 and culture it at 37℃ for 3 hours.
Then calculate the survival rate. If the strain is acid-tolerant, its survival rate is high.