First, Yunnan Sanqi
Yunnan is a famous hometown of medicinal materials in China, and its complex natural and geographical conditions are conducive to the growth of many kinds of medicinal materials. Notoginseng, Gastrodia elata, Cordyceps sinensis and other varieties enjoy high reputation at home and abroad.
Sanqi, also known as Tianqi, was called "gold does not change" by Li Shizhen, a famous pharmacist in Ming Dynasty. Panax notoginseng is a pearl in the treasure house of traditional Chinese medicine. In the Pharmacology Compendium of Materia Medica in the Qing Dynasty, it was recorded that "Ginseng is the first to tonify qi, and Sanqi is the first to tonify blood, which has the same taste, so it is called Sanqi, which is the most precious of Chinese medicine."
Panax notoginseng has a long history of application. In A.D. 1578, Li Shizhen recorded Sanqi in his immortal masterpiece Compendium of Materia Medica: "This medicine has only recently come out, and it is an important medicine created by gold in the people's army of the south, and the cloud has wonderful achievements"; "It is the medicine of Yangming Jueyin, so it can cure all diseases". In the Ming Dynasty in the middle of16th century, Notoginseng had been introduced to the southeast coast and the Central Plains, and it was famous as a special medicine for traumatic injury and promoting blood circulation and removing blood stasis at sea.
Notoginseng not only has the special effect of treating traumatic injury, but also has the function of nourishing and strengthening. Kunming used to have the franchise "Steamed Chicken with Sanqi" of Hua Kai's "Xiuyi". Nowadays, "Steamed Chicken with Sanqi" has entered banquets and families as a traditional flavor food and health food in Yunnan Province.
Second, the pharmacology and efficacy of panax notoginseng saponins
Modern pharmacological research shows that total saponins of panax notoginseng are the main effective components of panax notoginseng. Panax notoginseng saponins have the following pharmacological and pharmacodynamic effects:
Effect of 1 on hyperlipidemia
Clinical study on the effects of panax notoginseng saponins on reducing blood lipid and preventing thrombosis in patients with hyperlipidemia. Studies have shown that panax notoginseng saponins have obvious preventive and therapeutic effects on hyperlipidemia.
2, the role of high viscosity.
Patients with hyperviscosity were divided into panax notoginseng saponins group and enteric aspirin group. After 4 weeks 1 course of treatment,
3, the role of hypertension
Treating hypertension with panax notoginseng saponins can obviously reduce the elevated blood pressure and slow down the heart rate after 20 days of treatment. The results showed that panax notoginseng saponins could significantly reduce MDA, significantly increase SOD, increase erythrocyte deformability and reduce erythrocyte aggregation.
4. Anti-myocardial ischemia effect
The observation of that effect of Panax Notoginseng saponins on experimental myocardial ischemia show that Panax Notoginseng saponins can significantly improve the ischemic manifestations of body surface electrocardiogram, narrow the range of myocardial infarction, reverse the left ventricular diastolic dysfunction in patients with fatigue angina pectoris, and even return to normal.
5. Anti-arrhythmia
To observe the effect of panax notoginseng saponins on experimental arrhythmia. Animal experiments show that panax notoginseng saponins can significantly reduce experimental ventricular premature beats in rats, shorten the duration of arrhythmia, and significantly reduce the incidence of arrhythmia during reperfusion in rats with acute myocardial infarction.
6. Anti-atherosclerosis effect
To observe the effect of panax notoginseng saponins on atherosclerosis in rabbits. The results showed that Panax Notoginseng saponins could play an anti-AS role through anti-inflammatory and anti-oxidation, protect vascular smooth muscle cells from the influence of high-fat serum, and have a certain preventive and therapeutic effect on the occurrence and development of atherosclerosis.
7. Anti-thrombosis and improving microcirculation.
To study the effect of panax notoginseng saponins on ET- 1 and platelet function in patients with coronary heart disease. The results showed that panax notoginseng saponins could significantly reduce the surface activity of platelets, inhibit platelet aggregation and adhesion, prevent thrombosis and improve microcirculation.
8. Anti-cardiocerebral ischemia effect
Panax notoginseng saponins can be used for treating cerebral infarction and ischemic cerebrovascular disease. The results showed that Panax Notoginseng saponins had a good clinical therapeutic effect on acute cerebral infarction, and could significantly improve the brain edema during global cerebral ischemia or focal cerebral ischemia-reperfusion.
9. Promote the growth of hematopoietic cells
Panax notoginseng saponins can proliferate hematopoietic progenitor cells. It was also found that Rg 1 and Rb 1 in total saponins of Panax Notoginseng are effective monomers for promoting hematopoiesis, which can continuously promote the proliferation of granulocyte and erythroid hematopoietic progenitor cells in human bone marrow, and the effect on granulocyte progenitor cells is better than that on erythroid progenitor cells.
10. Anti-fibrosis
It was found that panax notoginseng saponins can delay the process of tubulointerstitial fibrosis and improve renal function. It was found that panax notoginseng saponins could delay the occurrence of alveolitis, which progressed slowly and hardly formed lung fibers.
To study the effect of panax notoginseng saponins on experimental liver fibrosis through animal experiments. The results showed that Panax Notoginseng saponins had obvious anti-hepatic fibrosis effect.
Protective effect of 1 1. on nerve cell injury
The protective effect of panax notoginseng saponins on model cells was observed by cytology, morphology and lipid peroxidation injury index. The results showed that Panax Notoginseng saponins had protective effect on nerve cell injury caused by energy metabolism disorder.
Third, the drug identity of panax notoginseng saponins-Xuesaitong
Panax notoginseng is widely used in the field of medicine and health care. Pharmaceutical enterprises have developed many well-known drugs, such as Yunnan Baiyao, Xuesaitong series, compound Danshen dripping pills, Pien Tze Huang and so on. Among them, Xuesaitong is an essential Chinese patent medicine for emergency departments in hospitals all over the country. In recent years, panax notoginseng saponins (Xuesaitong) have been widely used in hospitals, and its market share of cardiovascular drugs has increased year by year. Its market drug ranking rose from the 6th in 2004 to the 5th in cardiovascular drugs in 2006. Panax notoginseng saponins is the fastest growing Chinese patent medicine preparation in domestic sample hospitals in 2006.
At present, the State Food and Drug Administration (SFDA) has approved Chinese patent medicine preparations and compound preparations of Panax notoginseng and Panax notoginseng, which are produced by about 77 enterprises nationwide.
4. Panax notoginseng saponins are suitable for people (suitable for prevention and control)
1. People with hyperlipidemia, high blood viscosity, high cholesterol and hypertension.
2. People with liver injury such as alcoholic hepatitis, fatty liver, chronic hepatitis and cirrhosis.
3. Patients with cardiovascular diseases such as coronary heart disease, angina pectoris, arrhythmia and myocardial ischemia.
4. Patients with cerebrovascular diseases such as cerebral ischemia, hypoxia, cerebral hemorrhage, stroke hemiplegia and cerebral infarction.
5. People suffering from hypoxia and fatigue at high altitude.
6. People with trauma and Alzheimer's disease.
7. Many people with low immunity, such as the elderly, are weak, tired from work pressure and weak after surgery.
Five, the use of panax notoginseng saponins:
(1) People with "three highs" should take one tablet twice a day for three months, and then test all the indexes. After reaching the normal index, stop taking one pill a day for one month, stop taking one pill for three months, and repeat for one month to purify blood and maintain health.
(2) Comparison of taking methods between patients with liver disease and patients with "three highs".
(3) For patients with cardiovascular and cerebrovascular diseases, take one pill twice a day.
(4) To prevent altitude hypoxia and resist fatigue, it is advisable to take one pill twice a day during the journey.
(5) To prevent Alzheimer's disease, you should take one pill twice a day.
Because people eat a lot of foods with high fat, high protein and high cholesterol in their daily diet, the originally clean blood gradually becomes more and more viscous and flows more and more slowly, gradually forming hyperlipidemia, hypertension and high cholesterol, which leads to cardiovascular and cerebrovascular diseases; At the same time, due to the pollution and viscosity of blood (the nutrient source of human organs), problematic blood will lead to organ failure and various diseases. Therefore, healthy blood is the greatest guarantee of good health. Panax Notoginseng saponins can clean blood environment and purify blood by promoting blood circulation to remove blood stasis, inhibiting platelet aggregation and adhesion. Therefore, panax notoginseng saponins are the best health care products to prevent various diseases.
6. What is the difference between eating Panax notoginseng and eating Panax notoginseng saponins? How to take it best?
Short-term and small doses of Sanqi, Sanqi, Sanqi stewed chicken, stewed meat, etc. It will have good health care effect, but it is not suitable for long-term use. Because Panax notoginseng is cultivated artificially at present, there are many kinds of heavy metals harmful to human health in the soil of Panax notoginseng producing areas in Yunnan, especially in the 1960s, pesticides "BHC" and "DDT" were widely used in the land of producing areas, and slowly decomposed in the soil after 60 years. Therefore, it is not advisable to take Panax Notoginseng or Panax Notoginseng for a long time, and Panax Notoginseng saponins are extracted from Panax Notoginseng through bioengineering, thus removing heavy metals and pesticide residues in Panax Notoginseng, so for most people, Panax Notoginseng saponins can replace Panax Notoginseng for a long time.
Some people with stomach cold may feel stomach discomfort at first after taking Panax Notoginseng saponins, and the feeling of stomach discomfort will be eliminated after taking them frequently.
Instructions for use of panax notoginseng saponins capsules
How to take orally, 1-2 capsules each time, once in the morning and once in the evening, with warm water. Specification 0.3g/ capsule
Friendship: Yunnan Jinsanqi Pharmaceutical (Jiangdong Commercial Plaza, Beijing Road Extension Line, Kunming)