Liver injury disease defines that the liver is the largest substantive organ in the abdominal cavity and bears important physiological functions of the human body. Liver cells have poor hypoxia tolerance, so there are hepatic arteries and portal veins to provide rich blood supply, and there are large and small bile ducts and blood vessels to transport bile. It is located in the deep part of the upper right abdomen and protected by the lower chest wall and diaphragm. However, due to the large size and brittle texture of the liver, once it is destroyed by violence, it is easy to cause intra-abdominal bleeding or bile leakage, resulting in hemorrhagic shock and/or biliary peritonitis, and the consequences are serious. It is necessary to diagnose the disease in time and deal with it correctly. The diagnosis of open injury can be based on the location of the wound, the depth and direction of the wound path, and the diagnosis of liver injury is not difficult. Closed true hepatic laceration with obvious intra-abdominal hemorrhage and peritoneal stimulation is not difficult to diagnose. Only for subcapsular hepatic laceration, subcapsular hematoma and central laceration, it may be difficult to diagnose hepatic laceration if the symptoms and signs are not obvious. According to the comprehensive analysis of the injury and clinical manifestations, we should closely observe the changes of vital signs and abdominal signs. The following examination methods may be helpful for the diagnosis of diseases: (1) Diagnostic abdominal puncture is of great value in the diagnosis of abdominal organ rupture, especially the laceration of solid organs. Generally, blood that does not coagulate can be considered as visceral injury. However, when the amount of bleeding is small, false negative results may appear, so a negative puncture can not rule out visceral injury. When necessary, puncture at different parts and at different times, or diagnostic lavage for abdominal diseases, to help diagnose the disease. (2) Regularly measure red blood cells, hemoglobin and hematocrit, and observe their dynamic changes. If there is progressive anemia, it means internal bleeding. (3) B-ultrasound can not only find hematocele in abdominal cavity, but also help to diagnose subcapsular hematoma and intrahepatic hematoma, which is commonly used in clinic. (4) X-ray examination If there is subcapsular hematoma or intrahepatic hematoma, X-ray film or fluoroscopy can show that the liver shadow is enlarged and the diaphragm is elevated. If there is free gas under the diaphragm at the same time, it indicates that there is cavity organ damage. (5) Closed injury with unclear diagnosis by radionuclide scanning of liver, suspected subcapsular or intrahepatic hematoma, the injury is not urgent, and isotope liver scanning can be performed if the patient's condition permits. The liver of the patient with hematoma shows radioactive defect area. (6) Selective hepatic arteriography can be used for closed injuries that are really difficult to diagnose in some diseases, such as suspected intra-hepatic hematoma, and this method can be selected for those who are not very urgent. Signs with diagnostic significance can be seen, such as the formation of aneurysm of internal hepatic artery branch or the overflow of contrast agent. However, this is an invasive examination with complicated operation, which can only be carried out under certain conditions and cannot be used as a routine examination. The most common complication is infection, others are biliary fistula, secondary bleeding and acute liver and kidney failure. (1) Infectious complications include liver abscess, subphrenic abscess and incision infection. It is an effective measure to prevent infection to thoroughly remove inactivated liver tissue and pollutants, properly stop bleeding and arrange reliable and effective drainage. Once the abscess is formed, it should be drained in time. (2) Bile leakage from liver wound can cause biliary peritonitis or localized abdominal abscess, which is also a serious complication. The method to prevent bile leakage is to carefully ligate or suture the ruptured bile duct during operation and place a drainage tube. After bile leakage occurs, placing a "T" tube in the common bile duct for drainage can reduce the pressure in the bile duct and promote healing. (3) Secondary bleeding is mostly caused by improper wound treatment, leaving dead space or necrotic tissue and secondary infection, leading to blood vessel rupture or ligation line falling off and bleeding again. When the amount of bleeding is large, it is necessary to operate again to stop bleeding and improve drainage. (4) Acute liver, kidney and lung dysfunction is an extremely serious and difficult complication with poor prognosis. Most of them are secondary to severe compound liver injury, long-term shock after massive blood loss, long-term obstruction of liver blood flow and serious abdominal infection. Therefore, correcting shock in time, paying attention to blocking the time of blood flow to the liver, correctly handling liver wounds, arranging effective abdominal drainage and preventing infection are important measures to prevent this kind of multiple organ failure, and also the best method to treat multiple organ failure at present.