Coffee enema is said to be a way of anti-cancer and health preservation, but it has not been proved effective by the medical community at present. Most people who support coffee enema have benefited, such as beauty salons, health centers and hospitals with unknown qualifications. Consumers need to be cautious. At present, there are several reports of adverse reactions caused by coffee enema. Please don't try it until it is proved to be effective in the medical field. The potential risk of coffee enema is to affect the absorption of calcium and fat-soluble vitamins. Because coffee is not sterile water commonly used in hospitals, coffee enema can easily lead to bacterial infection, colitis and even sepsis. It is difficult to control the osmotic pressure of coffee solution to be consistent with body fluid during coffee enema, which may easily lead to electrolyte imbalance, dizziness, shock, brain cyst and even death. At the same time, too fast coffee infusion brings the risk of intestinal perforation, and overheating of coffee causes mucosal burns.