"It doesn't matter if you drink a little, it's good for your health!"

"Deep feelings, a stuffy! If you have shallow feelings, you should also have a look! "

As the Spring Festival approaches, there are more parties at the end of the year, and the abhorrent atmosphere of "drinking together" and "persuading wine" is once again put on the wine table.

When eating, if you say that drinking is not good, wine lovers may find a bunch of articles and documents that "drinking is good for health" from the Internet to testify for themselves: "Look! Scientists say drinking is good for blood vessels! Drinking is a kind of health! "

In the past, many serious journal studies found that drinking was negatively correlated with obesity, diabetes and Parkinson's disease. Some studies even show that drinking alcohol has an "optimal" intake, as long as it does not exceed the threshold, it will not be harmful to health.

However, a recent article on medRxiv platform found that there are many contradictions in the above research. For example, in genome-wide association studies, drinking is negatively correlated with diseases, but when analyzed by Mendel's randomization method, it is found that drinking will increase the risk of diseases!

One minute you say drinking is good, and the next you say drinking is not good. Which one should you believe? By consulting the literature, the researchers found a problem: some people lied on the questionnaire, and the deviation changed vertically.

First of all, "lying" in the questionnaire will affect the research results.

Questionnaire survey is a common method in scientific research. By analyzing the data of more than 450,000 people in the British Biobank, the researchers found that many people "lied" in the questionnaire, such as:

10.4 million people claimed to be "teetotalers" on the questionnaire, but they suffered from diseases closely related to drinking;

65438+100000 people indicated that they had drunk alcohol within one year in the questionnaire, but they filled in "0" on the amount of drinking.

Research shows that in epidemiological or genetic research, questionnaire survey is the main means to collect human behavior characteristics, but some participants will "lie" on the questionnaire, which will lead to false positives and ultimately affect the correctness of the results.

Secondly, the "vertical change of time" affects the judgment of scientists.

Research shows that compared with 10 years ago, people who abstain from alcohol and alcohol are sick. What's going on here? Can drinking really prevent diseases?

According to research and analysis, abstainers get sick because there are a large number of patients among abstainers. To put it simply, it is not "not drinking and getting sick", but "not drinking because of illness".

Later, by correcting false positives and vertical changes, the researchers found that drinking alcohol was positively correlated with the onset of diseases, that is, drinking less and getting sick more. The so-called "optimal drinking quantity" does not exist at all!

In 20 18, a study involving 28 million people in The Lancet also complained about drinking: drinking can not bring any health benefits! A small amount of drinking is also harmful to health! There is no such thing as drinking a little wine for health, and there is no such thing as a "safe amount"!

Studies have shown that drinking has become the seventh leading cause of death and disability in the world and the "number one killer" of young and middle-aged men. Every year, 2.8 million people in the world drown their sorrows by drinking, and China is the country with the largest number of deaths from drinking, with 700,000 compatriots "dying of alcohol" every year!

However, the author believes that there are always alcoholics who are unconvinced and think that life should be carpe diem and drink whatever they want, which is beyond others' control. In this regard, the author wants to say: drink, close your eyes and open them again, and maybe you can see the Lord of hell.

So, what are the hazards of drinking regularly?

1, carcinogenic

After drinking alcohol, ethanol can be converted into acetaldehyde in the body, and acetaldehyde has long been listed as a first-class carcinogen by the World Health Organization, ranking 1!

20 17 according to a research data of American Clinical Oncology Association, drinking is related to oral cancer, laryngeal cancer, esophageal cancer and liver cancer!

It is worth noting that many people in China will blush when drinking, because there is a mutation in the gene of acetaldehyde dehydrogenase 2 in East Asians, which is not easy to decompose acetaldehyde, resulting in poor alcohol metabolism, which makes a lot of acetaldehyde stay in the body and causes vasodilation! In this respect, people who blush after drinking alcohol have a higher risk of cancer.

2. Cardiovascular and cerebrovascular diseases

Can drinking soften blood vessels? Can also promote blood circulation? This is your illusion!

A study by The Lancet magazine followed 10 years, involving more than 500,000 people in China. The study shows that the more people drink, the higher the risk of hypertension and stroke. If you drink 40g every day, the risk of stroke will increase by 35%!

3. Alcoholic hepatitis

As long as you drink it, your liver will be "miserable"

Alcohol is mainly metabolized by the liver. Once the amount of alcohol consumed exceeds the decomposable capacity of the liver, liver cells will be damaged and eventually evolve into alcoholic hepatitis. If you do this for a long time, it will also lead to liver fibrosis, cirrhosis and even induce liver cancer!

Step 4 drink too much

Excessive drinking will turn the central nervous system from excitement to inhibition, from alcohol behaviors such as unconsciousness, nonsense, unstable gait and hurting others to death due to coma, multiple organ injury and circulatory paralysis!

In a word, drinking is harmful to health. Don't blindly believe in the study of "proper drinking is good for health" because of the causal relationship between the relevant facts in the study!

In addition, according to the author's understanding, some research funds that prove that "a small amount of drinking is good for health" are provided by major wineries ... people pay money to help others eliminate disasters. How convincing is the experiment?

Finally, the author reminds me that "drinking without touching" is the last word of health! Wine culture? Go and cool off!

# Breeze Project ##39 Health Super Group #