It is mainly related to various pill refining methods. The ancients had hoped to make a magic pill that would make people immortal and soar through the complicated combustion process of various mineral drugs. Although this idea is absurd and almost illusory, they also got some effective pills to treat diseases, which is the first in the research of human medicinal chemistry. Treatment of diseases, such as Hongshengdan and Baijiangdan, has been summarized clinically. This kind of works are mainly collected in Taoist classics, such as Wu Yi's Fang Dan Xun in Song Dynasty, Jin Lingzi's Dragon and Tiger Return to Dan, and the author's Huangdi Jiuding Classic. The earliest and most famous person who recorded alchemy was Bao Puzi written by Ge Hong in Jin Dynasty.