Component broadcasting
This product is a compound preparation, and its components are as follows: this product consists of two doses, A and B. The first dose contains polyethylene glycol 400013.125g;
Agent B contains 0. 1785g of sodium bicarbonate, 0.3507g of sodium chloride and 0.0466g of potassium chloride.
Character broadcasting
This product A is white powder; Agent B is white crystalline powder.
Indicating broadcast
1. Used to treat functional constipation;
2. Used for preoperative intestinal cleaning preparation; Preparation of intestinal cleaning before colonoscopy and other examinations.
Specification broadcast
Agent A: polyethylene glycol 400013.125g; Agent B: 0.1785g sodium bicarbonate, 0.3507g sodium chloride and 0.0466g potassium chloride.
Usage and dosage broadcast
1. Preparation: Take one packet of this product A and one packet of this product B and dissolve them in 125ml warm water to form a solution.
2. Administration method and dosage:
Treatment of functional constipation: adults take 125ml solution twice a day; Older people should start once a day, and take the same dose as adults or follow the doctor's advice if necessary.
Intestinal preparation: 250ml each time, once every 10- 15 minutes, until the water sample is discharged and the stool is clear. Take 3000ml orally at most.
Adverse reaction broadcast
When treating constipation, the adverse reactions of this product are diarrhea and paroxysmal abdominal pain. During bowel preparation, nausea, bloating, occasional abdominal cramps, vomiting and anal discomfort may occur after taking a large amount. Very few people will have allergic reactions such as urticaria, runny nose and dermatitis. The above adverse reactions disappeared immediately after drug withdrawal.
Taboo broadcasting
1. Patients with gastrointestinal obstruction, intestinal perforation, gastric retention, gastrointestinal bleeding, toxic enteritis, toxic Hirschsprung's disease and Crohn's disease are prohibited.
2. Those who are allergic to this product are prohibited.
Precautions broadcast
1. Do not add any other ingredients, such as condiments, to the solution during taking.
2. Use with caution in patients with severe ulcerative colitis.
3. This product should be used after the diseases in contraindications are really excluded.
4. When this product is used for intestinal cleaning, attention should be paid to:
(1) Patients should not eat solid food from 3-4 hours before taking the medicine to the end of the examination. Do not eat solid food for nearly 3 hours after taking the medicine.
(2) About 1 hour after taking the medicine, the intestinal movement is accelerated, and the patient may feel abdominal distension or discomfort. If the symptoms are serious, you can increase the interval or stop taking the medicine until the symptoms disappear, and then continue to use the medicine until the water sample is discharged.
(3) Strictly observe the preparation method of this product.
(4) It is best to start taking medicine 4 hours before the operation or examination, taking medicine for 3 hours, and emptying time 1 hour; It can also be taken the night before surgery or examination.
Drug broadcast for pregnant and lactating women
There is no research report. The advice can only be applied to pregnant women if it is very necessary.
Children's medication broadcast
Children under two years old should be carefully monitored when taking medicine to prevent dehydration and hypoglycemia.
Drug broadcasting for the elderly
Please follow the doctor's advice.
Drug interaction broadcasting
When this product is used for intestinal cleaning, other oral drugs taken before 1 hour may be washed away from the gastrointestinal tract without being absorbed.
Drug overdose broadcast
If overdose causes severe diarrhea, stop taking the medicine immediately. If constipation occurs again, you should start with a lower dose under the guidance of a doctor.
Pharmacology and Toxicology Broadcasting
Pharmacological action:
This product is a compound preparation of polyethylene glycol 4000 and electrolyte. Dissolve a part of the product (package A+ package B) in125ml water to form an isotonic solution. Polyethylene glycol 4000 combines with water molecules to form relatively stable hydrogen bonds. After entering the intestine, the water in the intestinal contents will not be excessively absorbed by the colon, thus lubricating the intestine, softening the feces, increasing the volume of the intestinal contents and promoting the normal physiological movement of the colon. Taking this product in large dose (2-3 liters) can play the role of intestinal lavage and lavage. In addition, the net exchange of water and electrolyte between this product and gastrointestinal mucosa is basically zero, so it can maintain the balance of water and electrolyte before and after defecation or intestinal cleaning.
Toxicological research:
There is no research data on the reproductive and genetic toxicity of polyethylene glycol, and the general toxicological research results do not show the systemic toxicity of polyethylene glycol 4000.