2 English reference Gui Lu Er Xian Jiao [Committee on Terminology of Traditional Chinese Medicine]. Terminology of Traditional Chinese Medicine (2004)]
Gui Lu er xian jiao [2 1 century bilingual dictionary of science and technology]
3. Summarizing the name of Guilu Erxian Gum, there are about two prescriptions with the same name.
4. The formula of the first volume of Medicine Fertilizer is simple, but the production process is complicated, especially why it is made of copper dish, and the role of copper in the production remains to be discussed. From the modern pharmacological analysis of each flavor of this prescription, it can be seen that the powerful regulation and promotion of this prescription on nerve, endocrine and immune functions almost involves all kinds of endocrine functions of the body, especially three drugs in this prescription can promote the development of sexual function and sexual organs, so it is considered that this prescription has a certain therapeutic effect on endocrine-induced dysplasia, sexual hypofunction and neurasthenia. Judging from its regulating effect on cell growth, reproduction and metabolic function, this prescription should have a certain therapeutic effect on anemia of various reasons, which needs further study. [ 1]
4. 1 Tortoise and Deer Erxian Gum, alias Tortoise and Deer Erxian Plaster, (Book 4 of the Secret of Living) and Erxian Gum (Book 8 of Miscellaneous Rhinoceros Candle).
4.2 Prescription antlers (killing antlers with fresh elk requires no solution or horse antlers; Ten catties, five catties (mashed), fifteen taels of ginseng and thirty taels of medlar.
Antlers (slaughtered with fresh elk, horns removed, red antlers removed, two-inch horns removed and chopped clean) 10 kg, tortoise plastron (unthreaded, washed and mashed) 5 kg, ginseng 15 kg and medlar 30 kg. [3]
Antlers (fresh elk kill horns, horse antlers don't need them, the brain tip bone is 6.6 cm, it's broken and split, and it's all used) 5 kg of tortoise plastron (string removed, washed and mashed) 2.5 kg of ginseng 450 g and Lycium barbarum 900 g.
4.3 Preparation method of cornu Cervi, tortoise shell and ginseng bag, soaking in running water for three days [2]. Use a lead can, such as a lead-free can, and put a large piece of lead under it. Put the horn into a jar, soak it in water for three to five inches, and seal it with yellow wax [2]. In an enlarged pot, mulberry firewood stayed up for seven days and seven nights. When cooking, add hot water to the tank once a day to avoid boiling, and add water to the pot five times a day. Take out the horn cake, wash it, and filter it to remove me, that is, antler cream and turtle paste [2]. Separate the clear juice, put 36 bowls of water for ginseng and Lycium barbarum into a copper pot until there is no water on the medicine surface, wring out the clear juice with a new cloth, pound my mortar with water, and boil it with 24 bowls of water as before; Filter, mash, boil, and so on for three times, taking me as tasteless [2]. Put the tortoise and deer juice together, put the medlar juice into the pot, and simmer until the water drops become beads, which is glue [2]. From the first month's day 10, you start drying sunscreen until the first day 17, and it will be full at night on the seventh day, so that you can collect the essence of the sun. If it rains for a few days this month, make up all the sun next month and let it dry in the shade [2].
Antlers and turtles were packed in bags and soaked in running water for three days. Use a lead can, such as a lead-free can, and put a large piece of lead under it. Put the horn plate in the jar, soak it in water for three to five inches, seal it with yellow wax, expand the pot and cook it with mulberry firewood for seven days and nights. When cooking, add hot water to the jar once a day, and don't let it boil. Add water to the pot five times a day, then take it out, wash it and filter it out. Its main ingredients are antler cream and tortoise shell cream. Clear juice is separated. In addition, put ginseng and Lycium barbarum into a copper pot and boil them with 36 bowls of water until there is no water on the medicine surface, wring clear juice with a new cloth, mash the mortar with water and boil it with 24 bowls of water as before; Filter, mash and boil for three times, and I will be tasteless. Put the soft-shelled turtle and deer juice into a pot and simmer until the water drops are beaded and gelatinous. Add 65438+4.5g to 9g on the first 10 day, and then empty the wine. [3]
Two kinds of antlers and tortoise shells, bagged and soaked in running water for three days. Use two lead cans (for example, lead-free cans, the bottom of which can hold a large piece of lead), put the horns into the cans, seal the height with water 10 ~ 15 cm, and seal 90 grams of yellow wax. In an enlarged pot, mulberry firewood was cooked for seven days and seven nights. When cooking, add hot water to the jar once a day to avoid boiling. Add water to the pot five times a day and night, take out the crispy horn, wash and filter to remove me (that is, antler cream and tortoise plastron), and put the clear juice separately. Add 9 liters of water to ginseng, Lycium barbarum and copper pot, boil until there is no water on the medicine surface, and wring the juice with a new cloth. Put the residue into a stone mortar and tamp it with a mallet, boil it with 3.5 liters of water, filter it, tamp it and boil it again, and repeat this for three times. Take my taste as tasteless, put turtle, deer juice and Lycium barbarum juice into a pot and cook with slow fire until the water drops become beads and become gel. Wait until the tenth day of the first month, and the sun will be full on the seventeenth or seventh day in the evening, and I will take a breath of the fine moonlight. If it rains for a few days this month, make it up next month. Let it dry in the shade.
4.4 Function Indications Turtle and Deer Erxian Glue has the effects of nourishing essence and blood, benefiting qi and strengthening yang. Treating men and women is really vain, and will not be pregnant for a long time; Extremely refined, wet dream, thin and qi-deficient, unable to see clearly. (infertility)
4.5 Usage and dosage of Guilu Erxian Gum: five cents on the first day, five cents on the tenth day, and added to San Qian. Under the hollow wine, this party's only son [2]. The whole medicine is refined and specialized, and constant service is acceptable [2]
Take 4.5g at the beginning of each dose, and add 1.5g on day 10 to 9g, then use alcohol on an empty stomach.
4.6 Prescription explains the syndrome of Guilu Erxian Gum, which is caused by deficiency of true elements and yin and yang essence and blood. Qi and blood are born in the spleen and stomach, while essence and blood are born in the liver and kidney. Only when qi and blood are not deficient and essence and blood are not damaged can the human body be full of energy. Deficiency of kidney essence leads to deficiency of true elements; Acquired spleen and stomach dystrophy, or post-illness disorder, leads to yin and yang essence and blood deficiency, so the body is emaciated, the waist and knees are weak, the eyes are dim, impotence and nocturnal emission are pregnant with infertility for a long time. The treatment should be replenishing essence and marrow, benefiting qi and nourishing blood, and nourishing yin and yang. The antler gum in the prescription is sweet, salty and warm, and it is good at warming kidney and strengthening yang, benefiting essence and enriching blood; Tortoise shell glue is sweet, salty and cold, and is good at replenishing essence and marrow, nourishing yin and nourishing blood. Two flavors are sentient products, which can tonify yin and yang, and tonify essence and blood, and * * * is the monarch medicine. Compatibility of ginseng to tonify the qi of spleen and stomach, thus enhancing the source of qi and blood; Lycium barbarum can benefit liver and kidney, replenish essence and blood, and help tortoise and deer, all of which are minister drugs. Four flavors are combined, yin and yang complement each other, and both qi and blood are taken into account, so it can prolong life and produce sperm and seeds. [3]
4.7 Clinical Application [3]
Guilu Erxian gum is a tonic of yin and yang, qi and blood, which can not only supplement the loss of liver and kidney, but also benefit the weakness of spleen and stomach. The main points of syndrome treatment are weakness of waist and knees, blurred eyes, impotence and nocturnal emission. If the spleen and stomach are weak and eat less loose stool, it should not be used.
4.7. 1 Add and subtract If dizziness occurs at the same time, add Chrysanthemum morifolium and Fructus Cannabis tomorrow to calm the wind and stop dizziness; For patients with frequent nocturnal emission, Fructus Rosae Laevigatae and Fructus Tribuli are added to tonify kidney and solidify semen.
4.8 Modern indications [4]
Dysplasia, severe anemia, neurasthenia and sexual hypofunction caused by endocrine disorders can all be treated with Guilu Erxian glue.
4.8. 1 The onset of neurasthenia is related to factors such as excessive mental stress or fear, which leads to insufficient cerebral cortex inhibition and headache, dizziness, irritability, difficulty in falling asleep or shallow sleep or insomnia; Secondly, the excitation function of cerebral cortex is insufficient, which is manifested as listlessness, lack of emotion, fatigue, inattention, memory loss, and difficulty in lasting work. The above two situations can also exist simultaneously; However, some organic diseases such as neurasthenia syndrome caused by brain tumor should be excluded.
4.8.2 Developmental abnormalities caused by endocrine disorders include many diseases, such as growth hormone deficiency (formerly called dwarfism), central diabetes insipidus, congenital hypothyroidism, congenital adrenal hyperplasia, diabetes, precocious puberty, etc. The causes of these diseases are complicated, but in the final analysis, they are all related to hypothalamus-pituitary-target gland axis lesions. Hypothalamus is an important part of central nervous system and the center of endocrine system. Most endocrine glands are innervated by nerves, and many hormones act directly on the nervous system as neurotransmitters, thus forming the nervous and endocrine systems. At the same time, the nervous system, endocrine system and immune system are interrelated and regulate each other, thus establishing the unified regulation and function of the body. The most special example between nerve-endocrine-immune system is the immune-hypothalamus-pituitary-adrenal axis. Cytokine IL 1 *** hypothalamus secretes adrenocorticotropic hormone and inhibits antibody production. Therefore, endocrine disorders and developmental abnormalities are related to neuroendocrine immune system diseases, so I will not elaborate here.
4.8.3 Severe anemia refers to hemoglobin.
4.8.4 Sexual hypofunction Sexual hypofunction mainly refers to nocturnal emission, impotence, premature ejaculation, * * * little or no * * *, and * * * no liquefaction. * * * is rarely seen in reproductive infection, but also in endocrine diseases such as hypothyroidism, Addison's disease, diabetes, pituitary diseases and sexual dysfunction, which makes * * * have obstacles; Varicocele can also cause testicular damage, thus causing spermatogenesis disorder; Biochemical factors such as environmental infection, long-term high-temperature operation, excessive cadmium, lead and zinc or poisoning can all affect the growth and maturity of * *; At the same time, the non-liquefaction of * * * is also an important cause of infertility. Nocturnal emission refers to the phenomenon of * * * when there is no * * activity, which is often caused by the excessive excitement of the cerebral cortex caused by * * * and long-term * * * and excessive * * * in pornographic film and television periodicals. Impotence refers to the inability of * * * to erect or the inability to erect firmly in the state of * * * and sexual excitement, so that * * * cannot be inserted. Impotence can be divided into functional impotence and organic impotence. Functional impotence refers to impotence caused by non-organic reasons, such as the inhibition of sexual excitement by cerebral cortex is strengthened and the excitability of spinal erection center is reduced. Organic impotence refers to impotence caused by organic diseases of nerve, blood vessel, endocrine and urinary system. The former is more common in * * * harsh environment, cold relationship between husband and wife or fear of the woman, which is caused by long-term mental stress, or long-term * * *, nervous system failure due to excessive excitement, decreased excitability of spinal cord erection center, or weakness, excessive mental work and autonomic nerve dysfunction. The latter is caused by organ system diseases, drug action or surgical trauma.
4.9 Pharmacological Effects of Guilu Erxian Gum [5]
4.9. 1 Effect on immune function The monarch drug Antlers can significantly increase the weight of thymus, promote the proliferation of T lymphocytes, significantly increase the phagocytosis percentage and phagocytosis index of macrophages, and significantly antagonize the inhibitory effect of chemotherapy drugs on macrophage activity. For hyperthyroidism caused by T3, thymus atrophy, decreased cortical lymphocytes, disappearance of cortical boundary, decreased lymphocyte transformation rate and decreased serum IgG antibody, Guiban decoction can significantly antagonize the above-mentioned immune organ damage and function inhibition, increase thymus weight, restore normal tissue structure, and improve leaching rate and serum IgG antibody. Tortoise shell extract can also increase the phagocytic index of macrophages, increase the number, volume and pseudopodia of macrophages, indicating that Tortoise shell has the function of improving cellular immunity, humoral immunity and nonspecific immunity. At the same time, Biejiajian Pill can obviously promote the growth and proliferation of human embryonic lung diploid fibroblasts, and anti-aging Lycium barbarum can enhance nonspecific immunity, humoral immunity and cellular immunity, especially when the immune function is low. Macrophages participate in both nonspecific immunity and specific immunity, and the number and activity of C3b and f C receptors on their surfaces can be used as indicators of cell function, while Lycium barbarum polysaccharide can increase the number and activity of C3b and f C receptors, and can antagonize the inhibitory effect of hydrocortisone acetate on C3 and Fc receptors. At the same time, Lycium barbarum polysaccharide can promote DNA synthesis, cell division and proliferation, and has antagonistic effect on cyclophosphamide inhibiting bone marrow hematopoietic function; Lycium barbarum also has a certain regulatory effect on the reaction of IgE antibody; Lycium barbarum can enhance the activity of B cells, promote the differentiation and proliferation of B cells, increase the contents of IgG, IgM and complement C4 in serum, and significantly increase the proliferation of T lymphocytes. Lycium barbarum polysaccharide can selectively enhance the immune response mediated by T lymphocytes, especially thymic T lymphocytes, enhance the activity of inhibitory T cells (TS), and significantly regulate the decrease of 3HTdR incorporation in thymocytes induced by concanavalin. The number of TH cells in immunosuppressed animals also increased significantly after the application of Lycium barbarum. Increasing the ratio of TH/TS significantly increased the low level of IL-2 and enhanced the expression of IL-2 on the surface of T lymphocytes. At the same time, the water extract of Lycium barbarum can induce and promote the production of IL-6 by LPS-induced whole blood cultured cells and promote LPS-induced THF. Ginseng has a wide range of effects on cellular immunity and humoral immunity. Ginsenosides and ginsenosides are active components of ginseng to regulate immune function, which can improve immune function not only for normal animals, but also for animals with low immune function. Ginseng flower saponin can increase the concentration of specific antibody and the levels of IgG, IgM and IgA in serum. Increase serum IL-2 content, supplement C3 and C4, and increase the weight of immune organs; Ginseng can promote the phagocytosis of reticuloendothelial system, promote the transformation of T and B lymphocytes into mitogen lymphocytes, increase the proliferation of spleen T cells to ConA, promote the production of IL-2, and improve the activity of spleen NK cells. Ginseng polysaccharide can promote phagocytosis of reticuloendothelial system, induce TNF and anti-complement activity.
4.9.2 Effect on cell function A large number of experimental results prove that cyclic nucleotide system is one of the important regulatory systems at the molecular level, and cAMP and cGMP play a very extensive and important role in regulating cell function. cAMP is the main one in patients with yin deficiency, while cGMP is the main one in patients with yang deficiency. Tortoise shell can affect cell function by regulating cyclic nucleotide system and reduce the reactivity of cAMP in patients with yin deficiency; The abnormality of β adrenergic receptor cAMP system ((βARcAMP)) is also the pathological change of Yin deficiency syndrome, and the tortoise plastron can adjust this system to make it return to normal. Guiban decoction can obviously inhibit the increase of Na+K+ATPase activity on erythrocyte membrane and make it return to normal or close to normal. Tortoise shell can promote the proliferation of neural stem cells after focal cerebral ischemia, significantly increase bone mineral density and bone calcium and magnesium content, increase serum AKP, and significantly reduce serum copper/zinc ratio. Pilose antler can significantly increase the content of hemoglobin in blood, which has obvious blood enriching effect. At the same time, antler has anti-osteoporosis effect and can increase bone density. Lycium barbarum L. increased the intracellular cAMP content and decreased the cGMP content, thus restoring the abnormal cell function to normal. Lycium barbarum can also promote DNA synthesis and cell division, promote cell proliferation, improve the DNA repair ability of the elderly, protect the damage of genetic material, and also play a role in growth. Ginseng root saponin, ginseng fruit saponin and ginseng stem and leaf saponin can promote the proliferation of embryonic lung fibroblasts in the elderly, transform "undivided" cells in the aging cell population into "divided" cells, and shorten the cell division cycle; Ginsenoside can inhibit the proliferation of tumor cells; Sesquiterpenes in ginseng volatile oil can inhibit the metabolism of nucleic acid and sugar in cancer cells; For testis, bone marrow and other organs, ginsenoside can not only synthesize RNA and protein, but also promote DNA synthesis and RNA synthesis in liver. Ginseng promotes the mitosis of bone marrow cells by promoting the synthesis of DNA, RNA, protein and fat in bone marrow, and increases the hematopoietic function of bone marrow and red blood cells and white blood cells; Ginseng significantly increased the productivity of human bone marrow stromal cell community and promoted the proliferation of erythroid progenitor cells and granulocyte progenitor cells. It can significantly promote bone marrow hematopoietic stem cells, promote the differentiation of erythroid blood cells, and promote the formation of mixed colonies composed of erythroid, granulocyte and megakaryoid.
4.9.3 Effects on nervous system and endocrine system The serum T3 and T4 values of hyperthyroidism patients are obviously increased, and the turtle shell decoction can be obviously reduced, in which T4 returns to normal, the weight of thyroid gland is obviously reduced, and turtle shell can make it return to normal, indicating that turtle shell can effectively reduce the thyroid function of hyperthyroidism animals; At the same time, Biejiajian Pill can restore the Na+K+ATPase activity of erythrocyte membrane to normal, and inhibit the increase of Na+K+ATPase activity by T3, thus inhibiting the increase of metabolism and the acceleration of protein decomposition in patients with hyperthyroidism. Guiban decoction can obviously restore thymus function, increase adrenal weight, increase the thickness of adrenal cortex globular zone, increase the cell volume of fascicular zone and increase cytoplasm, but significantly reduce plasma cortisol and urine 17 hydroxysteroid, which shows that it can effectively reduce adrenal cortex function in hyperthyroidism animals. It can promote the proliferation of neural stem cells after focal cerebral ischemia and alleviate the symptoms of nerve injury. Lycium barbarum can enhance immune function by regulating the coordination of hypothalamus, sympathetic nerve and adrenal cortex. Lycium barbarum L. has a growth hormone-like effect, which makes muscles plump and weight gain, and its guanidine derivatives also have a significant and lasting hypoglycemic effect; Lycium barbarum not only has estrogen-like effect, but also can significantly increase blood testosterone level, indicating that Lycium barbarum can promote gonadal function. Lycium barbarum can also increase intracellular cAMP content, significantly reduce cGMP content, and increase cAMP/cGMP ratio, which is very beneficial to the recovery of normal physiological regulation function of patients with yang deficiency. Ginseng can excite hypothalamus-pituitary-adrenal cortex axis. Ginsenosides can increase the levels of plasma corticosterone and ACTH by acting on the anterior pituitary, and the content of cAMP in adrenal gland also increases. Ginsenoside Rg 1 can also release ACTH from the anterior pituitary through the second messenger cAMP. Ginseng can also stimulate other endocrine organs and stimulate hypothalamus-pituitary-gonad axis, thus promoting the secretion of sex hormones and the development of sexual organs; Panaxadiol can increase the release of catecholamine mediator in adrenal gland; Ginseng soup can reduce the levels of serum thyroxine and corticosterone and restore them to normal levels. Ginseng extract can promote the release of insulin from pancreas, and ginsenoside Rb2 can normalize sugar utilization by correcting the abnormal activities of glucose 6 phosphatase and glucokinase. Ginseng polysaccharide b can increase insulin secretion and improve the sensitivity of tissues to insulin; Ginseng polysaccharide A can inhibit the activity of liver glucose 6 phosphatase, increase the activities of liver phosphorylase, glucose 6 phosphate dehydrogenase and phosphofructokinase, accelerate the utilization of sugar and reduce glycogen synthesis. Ginseng glycopeptide first binds to β receptor and transmits information to hepatocytes through cAMP, which leads to the increase of phosphorylase activity and the decrease of glycogen. CAMP also transmits information to mitochondria, increases the activity of enzymes involved in sugar oxidation, and accelerates the oxidation and utilization of sugar, so it can reduce blood sugar in many ways. Ginseng can dilate cerebral vessels, increase cerebral blood flow after cerebral ischemia and reperfusion, reduce calcium deposition, alleviate brain edema and promote the recovery of reperfusion brain injury; It can also increase the intake of glucose by the brain, reduce lactic acid, pyruvate and the ratio of lactic acid to pyruvate, and make the utilization of glucose change from anaerobic metabolism to aerobic metabolism, so that the brain can make rational use of glucose oxidation ability; Ginseng can promote the synthesis of RNA and protein in brain, promote the development of cranial nerve cells, increase the weight of brain and the thickness of cerebral cortex, increase the number of synapses in the upper layer of pyramidal cells in CA3 area of hippocampus, and improve the function of hippocampal neurons. At the same time, ginseng can protect nerve cells, prolong their survival time and reduce mortality; Ginseng can regulate the excitement and inhibition of the central nervous system. By strengthening the excitement process of cerebral cortex, we can balance the excitement and inhibition process, make the nerve activity with neurological disorders return to normal, improve the flexibility of the nerve activity process and improve the efficiency of mental work. At the same time, ginseng can enhance learning and memory by promoting protein synthesis in brain tissue, and further research proves that ginsenoside can inhibit the damage of hippocampus cells caused by hypoxia. Pilose antler can increase dopamine content in brain, and its extract can inhibit the increase of prolactin (PRL) caused by diethylstilbestrol, mammary gland hyperplasia caused by estradiol in mice, and reduce the content of vitamin C in adrenal gland, indicating that it has an exciting effect on adrenal cortex function. At present, there are few modern pharmacological studies on antler, which are limited to hematopoiesis, immunity and anti-fatigue. However, it is reported that Lujiao Mixture has a certain therapeutic effect on 58 cases of congenital cranial fissure and spina bifida complicated with cerebrospinal fluid, and 45/58 cases have been cured. It is worth noting that the clinical application of velvet antler is often a substitute for velvet antler. Although its function is weaker than that of velvet antler, it has the same pharmacological effect as velvet antler. In addition to promoting the metabolism of glucose and nucleic acid protein, improving cardiovascular function, promoting hematopoiesis, antioxidation, improving immune function and anti-inflammation, velvet antler also has the stress effect of promoting the synthesis of adrenocortical hormone, which has a * * effect on the cerebral cortex and promotes learning and memory; At the same time, pilose antler contains androgen and follicle hormone, which promotes growth and development and improves the working ability of the body; Pilose antler can increase the weight of testis, epididymis and seminal vesicle of young rats or normal rats, and promote the growth of various glands. Pilose antler can promote the secretion of pituitary-gonad axis and increase plasma testosterone; Pilose antler acts on the division of type A spermatogonia, restores the abnormal spermatogenesis process and shortens the recovery period of damaged testis.
4.9.4 Anti-oxidation and anti-aging effects Guiban decoction can resist the increase of serum copper in Yin deficiency syndrome, but it has no effect on serum zinc, resulting in the decrease of serum copper/zinc ratio, and copper is the catalyst of redox system in the body, so Guiban decoction can inhibit the oxidation reaction of the body and improve the hypoxia tolerance of the body. Especially in the process of making this recipe, ginseng and medlar are boiled in copper pots, and the mechanism may be here. In addition, the study found that copper deficiency can induce small cell hypochromic anemia, neutrophil maturation disorder, vascular wall elastic fiber damage, bone lesions, and induce myocardial injury. Copper deficiency will make babies grow poorly and reduce their immune function. Although there is little research on antlers in modern times, antlers, as a substitute for antler, may have some effects of antler. Antlers have obvious antioxidant effects, which not only enhance SOD activity, improve the ability to capture free radicals, but also inhibit lipid peroxidation. Lycium barbarum polysaccharide contained in Lycium barbarum can resist free radical peroxidation, reverse damaged membrane potential and prevent mitochondrial aging. Lycium barbarum extract can obviously inhibit the production of LPO in mouse liver homogenate, increase GSHPx activity in blood and erythrocyte SOD activity, decrease serum LPO and increase GSHPx activity, so Lycium barbarum has anti-aging effect. At the same time, Lycium barbarum decoction can also improve the hypoxia tolerance and DNA repair ability of the elderly. Ginseng contains a variety of antioxidant substances, which can regulate physiological functions such as nerve, endocrine, immune function and substance metabolism. Ginseng maltitol, salicylic acid and vanillic acid all have obvious antioxidant effects. Maltitol can also capture free radicals and reduce the exposure of sulfhydryl groups in membrane proteins, thus stabilizing the structure of membrane proteins. Panax ginseng polyacetylene can inhibit lipid peroxidation of microsomes; Ginsenosides in roots, stems and leaves of ginseng can increase the activities of SOD and CAT, and decrease the content of lipid peroxide. Ginsenoside can inhibit the damage of free radicals to vascular endothelial cells and antagonize the damage of oxygen free radicals to myocardium. Panaxadiol saponins can improve SOD activity and inhibit brain injury caused by cerebral ischemia and reperfusion after ischemia. Ginseng has anti-stress effect, can increase the tolerance to hypoxia, low temperature and high temperature, and has positive effects on heat stress, noise stress and light stress. Ginsenosides in the roots, fruits, stems and leaves of ginseng can promote the proliferation of human embryonic lung fibroblasts in the elderly, transform "undivided" cells into "divided" cells in the aging cell population, and shorten the cell division cycle.
4.9.5 Effects on cardiovascular and hemorheology The tortoise plastron has obvious anti-hyperlipidemia and anti-atherosclerosis effects, which significantly antagonizes the increase of plasma viscosity, and also has the effects of anticoagulation and increasing coronary blood flow. Although the research is less and weaker than velvet antler, velvet antler can be used as a substitute for velvet antler. Moderate dose of alcohol extract of pilose antler significantly enhanced isolated heart activity, increased cardiac contractility, accelerated heart rate, increased coronary blood flow, and made the heart function recover more obviously from fatigue and failure, thus achieving the functions of strengthening the heart, improving microcirculation and improving various functions and tolerance of the body. It is speculated that although velvet antler is not as good as velvet antler, it may have a similar effect on cardiovascular function as a substitute for velvet antler. The latest research proves that velvet antler extract can improve myocardial contractility and increase cardiac output. Lycium barbarum can significantly reduce blood cholesterol, and Lycium barbarum water extract can reduce the contents of malondialdehyde, endothelin and calcitonin gene-related peptide in plasma and blood vessels, thus having the effect of lowering blood pressure. Ginseng can promote the release of catecholamine, inhibit the activity of myocardial Na+K+ATPase, increase Na+Ca2+ exchange and increase Ca2+ influx, so it has a cardiac glycoside-like effect. Ginseng can enhance myocardial contractility, increase cardiac output, increase coronary blood flow, slow down heart rate, and has anti-arrhythmia effect. Ginseng has anti-hypoxia and myocardial protection, which is mainly related to its ability to reduce myocardial oxygen consumption and increase coronary blood flow, while reducing the affinity of hemoglobin for oxygen and releasing more oxygen to tissues is another reason for ginseng to improve the anti-hypoxia ability of the body. Ginsenoside can reduce the range of myocardial infarction, inhibit the activity of creatine phosphokinase in plasma and reduce the ratio of PGI2/TXA2. Ginseng can dilate cerebral artery, coronary artery, vertebral artery and pulmonary artery and improve the blood circulation of these organs and tissues. Ginseng has a biphasic effect on blood pressure, which is related to dose and functional status. A small dose of raising blood pressure and a large dose of lowering blood pressure can not only lower the blood pressure of patients with hypertension, but also increase the blood pressure of patients with hypotension and shock. Ginseng has antagonistic effects on hemorrhagic shock, anaphylactic shock and cardiogenic shock, and can increase myocardial contractility and heart rate of hemorrhagic shock. Ginsenoside has a dose-dependent inhibitory effect on the conversion of fibrinogen to fibrin induced by plasmin. Panaxadiol saponins can significantly reduce whole blood viscosity and inhibit platelet aggregation, and inhibit platelet aggregation induced by ADP, thrombin and arachidonic acid by blocking PG metabolism and Ca2+ antagonism. Ginsenosides Rg3 and Rg 1 are the main components that inhibit platelet aggregation, so ginseng has the effect of inhibiting thrombosis.
Body surface area calculator body mass index calculation and evaluation of female safety period calculator expected date calculator normal weight gain during pregnancy medication safety classification (FDA) five elements and eight characters adult blood pressure evaluation body temperature level evaluation diabetes diet suggestion clinical biochemical common units conversion basal metabolic rate calculation sodium supplement calculator iron supplement calculator prescription common Latin abbreviations quick check pharmacokinetics common symbols quick check effective plasma osmotic pressure calculator alcohol intake calculator.
Encyclopedia of medicine, count now!
4. 10 Source Yi Bian Volume 1
5. Selected Prescriptions of Famous Doctors in Beijing, with the prescription of Guilu Erxian Gum 5. 1, with the name Guilu Erxian Gum.
5.2 Tortoise and Deer Erxian Gum alias Tortoise and Deer Gum
5.3 It consists of 800 taels of antlers, 800 taels of tortoise shells, 80 taels of rock sugar, 48 taels of yellow wine and 24 taels of sesame oil.
5.4 Efficacy: replenishing qi and blood, and strengthening the body.
5.5 Indications: Qi deficiency and blood deficiency, bone steaming and hot flashes, mental fatigue.
5.6 Usage and dosage: 23 yuan for each serving of Turtle Deer Erxian Gum, stewed with yellow wine; Or plain water will do.
5.7 In the preparation method, firstly, the antlers are sawed into 34-inch sections, soaked for 4 days, and then taken out. In addition, the tortoise shell was soaked for 7 days, washed with clear water, taken out, fried in sugar and wine into glue, put in a jar, cooled and solidified, and cut into small rectangles.
5.8 attention