From a biological point of view, insects can be regarded as the real hosts of these viruses, but they are still regarded as the vectors of these viruses. One of the reasons is that these viruses have established a balanced relationship with insects. Although they can proliferate in insects, they generally do not show pathogenicity to insects.

In biological application, the following types of biological virus agents have been used in various production activities. Several insect virus preparations have been sold in the international market, such as cotton bollworm nuclear polyhedrosis virus insecticide. In China, nuclear polyhedrosis virus was used to control cotton bollworm, inchworm, caterpillar, tea caterpillar, gypsy moth, armyworm, Spodoptera litura and flat thorn moth, granular virus was used to control Pieris rapae, Plutella xylostella, black cutworm and tea leaf roller, and qualitative polyhedrosis virus was used to control Dendrolimus punctatus.

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