Intravitreal injection of anti-vascular endothelial growth factor drugs is the first-line treatment for ocular fundus diseases at present, that is, intraocular injection can effectively inhibit angiogenesis, reduce vascular leakage and eliminate tissue edema, thus achieving the purpose of improving vision.
The growth, bleeding and exudation of new blood vessels in macular area (the place that determines visual quality) are like weeds. Vascular endothelial growth factor (VEGF) can promote the growth of new blood vessels, so anti-VEGF drugs can eliminate VEGF from the source and "weed out the roots" of new blood vessels, thus protecting the function of macula.
Anti-VEGF therapy requires a shot every month for three months.
These three needles are the basis of long-term benefit of vision, which can improve vision to the greatest extent. This is the basic requirement of the course of treatment and the standardized usage of drug instructions.
In the spring breeze, they grow taller again. Like weeds, new blood vessels may regenerate, so there is no "1 needle spirit".
On the basis of monthly 1 needle for three consecutive months, the study shows that the average number of anti-VEGF treatment needles in the first year reaches 5, which can ensure long-term benefits.
If there is no initial 3-needle continuous treatment every month, the long-term vision will decline instead of rising.
If you sew less than 5 stitches in the first year, the visual gain is not as good as that of patients who have sewed 5 stitches110.
Regular OCT examination every month is more conducive to determining the start time of treatment.
What tests do I need to do when I return to the clinic every month?
Visual inspection to determine visual changes.
OCT examination, timely detection of macular edema changes. Relying on patients' self-perception of visual changes is more accurate and convenient for timely treatment.
Fundus fluorescein angiography can detect the risk of neovascularization in time.
Regular follow-up and timely treatment can strive for the best vision.
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Treatment effect
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WAMD: Wet age-related macular degeneration, a fundus disease.
The vision of wAMD patients can be effectively improved after anti-VEGF treatment, and the vision can be improved even better after repeated anti-VEGF treatment.
Experiments show that receiving anti-VEGF drugs can quickly improve vision. After 24 months of maintenance treatment, vision has been significantly improved and is very stable.