No, German Essentiale healthy heparin is refined from soybean extract, which is naturally non-irritating. Drug-induced liver injury usually refers to the damage caused by its metabolites to liver cells. However, it is extracted from Yishanfu heparin factory in Germany, and its metabolites will not damage the liver, but have the effect of repairing damaged hepatocytes and protecting the liver. Moreover, Yi Shanfu has a history of protecting the liver for 50 years and should be safer. I'm glad you can adopt my answer. You can keep asking questions. Thank you.