Now that people's living conditions are better, there are more and more fat babies. But with the change of aesthetic concept, thinness is the real beauty of bone feeling. So many fat babies like diet pills that can make their bodies thinner faster. Of course, the market is full of fake and shoddy diet pills, which makes many fat babies cheated. The US Food and Drug Administration has only approved one diet drug, and that is orlistat.
At present, for a long time, "keep your mouth shut and keep your legs open" is still the best way to lose weight. At present, only the lipase inhibitor orlistat, the newly listed 5- hydroxytryptamine 2C receptor agonist chlorocasein and the compound diet drug Qsymia (sustained release agent containing phentermine and topiramate) have been approved by the US Food and Drug Administration for long-term use. 20 10 Four new drugs reported to the US Food and Drug Administration were rejected for safety reasons. Therefore, safety has become the biggest challenge in the research and development of diet pills, and it is also a difficult problem that must be overcome.
At present, there are mainly two kinds of slimming drugs on the market, pancreatic lipase inhibitors and appetite inhibitors acting on the central nervous system.
Appetite inhibitors are limited because they can cause adverse reactions in the nervous system. Orlistat, a pancreatic lipase inhibitor, can reduce weight by inhibiting the activity of pancreatic lipase and further inhibiting the decomposition and absorption of fat in food. However, it will cause lipodiarrhea and lead to the lack of fat-soluble vitamins. Recently, it has also been reported that it can cause liver function damage. Although the central nervous system appetite suppressants lorcaserin and Qsymia have become the first batch of diet pills approved by the US Food and Drug Administration since 13, there are still safety uncertainties in the brain center and cardiovascular system. At present, there are not many choices in the diet pills market. If there is a diet drug with good curative effect and low adverse reactions, its market will be significantly expanded.
Three kinds of people can take diet pills. 1. Only over 30% overweight and moderately obese people can consider taking diet pills, and pay attention to diet regulation and exercise. 2. Obese people who have undergone strict diet control and exercise therapy will gain weight after half a year if they start to lose weight, but for various reasons. At this time, it is more appropriate to combine diet pills with treatment. 3. For people who have difficulty in diet treatment and control, such as some obese people with peptic ulcer, diet pills can also be added to consolidate the weight loss effect. However, people who have undergone gastrointestinal surgery or have biliary tract diseases are not suitable for taking orlistat to lose weight.