The calories consumed in a five-kilometer run depend on several factors, including the weight, speed and running efficiency of the runner. Generally speaking, the calories consumed by running can be estimated by the following formula:

[\text{ calorie consumption (calories)} = \text{ weight (kg)} \times \text{ distance (km)} \times 1.036]

For example, if a 70kg person runs 5km, the calories consumed are: [70 \ text {kg} \ multiplied by 5 \ text {km} \ multiplied by 1.036 = 363.6 \ text {calories}].

This is only an estimate, and the actual consumption may vary from person to person. The intensity and terrain of running will also affect calorie consumption. For example, running on slopes usually consumes more energy than running on flat ground.