Refurbished freckle cream actually disturbs customers' sight, just like cosmetics, which can only cover spots, but can't eradicate them. Chemical peeling method has a high recurrence rate of spots, which is easy to damage the skin and leave scars. Most of them appear in beauty salons, such as medicine, traditional Chinese medicine and DIY freckle removal, which is inefficient, unable to freckle and takes a long time. Noble beauty salons have no medical qualifications. Traditional freckle removing equipment and common plastic surgery institutions continue the traditional freckle removing technology, and laser treatment can make skin scab and fall off at spots. There is no core technology, but APSC pluripotent cells are introduced into the basement to focus on nursing dull skin. The comprehensive therapy of facial rejuvenation with APSC pluripotent cells-freckle removal-is to purify, separate and cultivate APSC pluripotent cells through high-tech means in the laboratory. Introducing multifunctional cells and various cytokines into the deep layer of facial skin can stimulate the generation of a large number of collagen and the recombination of fibroblasts, secrete a large number of new cell matrix components, promote the increase of blood flow, rapidly metabolize waste materials such as prominent elements, inhibit and reduce the generation of pigmentation, and achieve the effect of skin rejuvenation and whitening.