"The skin of the East, the bone of the West" sounds mysterious, but it is easy to be separated and easier to understand from the perspective of painting and calligraphy.

Western lithofacies in painting refers to more three-dimensional facial features and more obvious highlights and shadows. Comparing the ancient beauty map of the past with the ancient beauty map of the present, it should be easy to feel the difference between them.

Western bone stereoscopic aesthetics emphasizes the prominence of the bridge of the nose and the shadow of the inner corner of the eye.

The appearance of Europeans and Americans is genetically three-dimensional, but they often bring their own buff of bone overgrowth.

Not bad for men, but a little masculine for women. Such as a high nose and a flat forehead.

The team of Wang Sijia, a researcher from Shanghai Institute of Nutrition and Health, China Academy of Sciences, an academician from China Academy of Sciences, and Professor Li Jing from Fudan University, together with scientific research institutions at home and abroad, conducted in-depth research on this issue. In the largest East Asian population data so far, the correlation between head and face phenotype and genotype was analyzed by a set of automatic quantification methods based on image analysis and computer algorithm. From the perspective of heredity and evolution, this paper analyzes the hot spots of human head and face phenotypic differences, reveals the genetic mechanism of some unique facial morphology in East Asia, and locates the genetic factors that cause the differences between Europe and Asia.

The morphology of human head and face is highly heritable. What genetic mechanism regulates facial differences between people? Using multiple canonical correlation analysis, the researchers located 244 genetic variations affecting the head and face morphology of East Asian people, and confirmed that facial features, as typical complex traits, were influenced by multiple genes. Through the cooperation with the European team, it is further found that the difference signal between Asia and Europe may be the frequency change caused by the same function.