8÷÷÷500 per bottle = 0.016 (yuan),
Small bottles are 3.4 ÷ 200 per bottle = 0.017 (yuan),
So it is cheaper to buy a big bottle as much as possible;
A * * * Drinks needed: 300×8 = 2400(ml););
You can buy two large bottles, leaving 400 ml. If you buy 1 bottle, you need 8 yuan. If you buy 2 vials, you need 3.4×2=6.8 yuan.
So buying two large bottles and two small bottles is the most cost-effective, and it costs:
15.4×2+3.4×2
=30.8+6.8
=37.6 (yuan)
Answer: It is the most cost-effective to buy two large bottles and two small bottles, 37.6 yuan.