Fruit category

Evodia rutaecarpa with different names (a convenient prescription for herbs and plants) and Zuo Li (a record of Wu Ji in Nanning).

The source is the immature fruit of rutaceae plant Evodia rutaecarpa.

Plant morphology Evodia rutaecarpa, also known as: pepper, smelly pepper, tree pepper, qi pepper, Qu Yaozi, tea spicy.

Evergreen shrubs or small trees, 2.5 ~ 5 meters high. Young branches, leaf axes and petioles are densely yellow-brown villous. Singular pinnate compound leaves, opposite; Leaflets in 2-4 pairs, ovoid to ovoid, 5- 15cm long and 2.5-6cm wide, with short and sharp tips, wedge-shaped to round base, entire, rarely inconspicuous circular serrations, densely covered with yellowish villi on both sides, thick paper or paper with oil spots. Flowers unisexual, dioecious, cymes, occasionally conical, terminal; Floral axis has 2 bracts at the base and scales at the upper bracts. The flowers are small, yellow and white. Sepals 5, broadly ovate, with yellowish pubescence outside; Petals 5, rectangular, densely white villous inside; The stamens of male flowers are 5, longer than petals, the anthers are basifixed, oval, the filaments are hairy, the degenerated ovary is slightly triangular and hairy, and the apex is 4 ~ 5-lobed; The female flower is large, with 5 staminodes, scales, the ovary is superior, spherical, carpels are usually 5, the style is short, the stigma is head-shaped, the capsule is oblate, about 3 mm long, and the diameter is about 6 mm. It is purplish red at maturity, with glandular spots on the surface, and each carpel 1 seed is oval, black and shiny. The flowering period is from June to August. Fruit-bearing period: September ~ 65438+ 10.

Wild in mountains, roadsides or sparse forests. Distributed in Changkang River Basin, South China and Shaanxi.

The roots (roots of Evodia rutaecarpa) and leaves (leaves of Evodia rutaecarpa) of this plant are also used as medicine, each with its own details.

Harvest from August to1October, when the fruit is dark green and the carpel has not been separated. Take it off and dry it in the sun to remove impurities. In case it rains, dry it with a low heat kang.

The dried fruit of medicinal materials is pentagonal oblate, with a diameter of 2 ~ 5 mm and a height of about1.5 ~ 3 mm. Its surface is green or brownish green, rough, with fine wrinkles and mane eyes (oil chamber). The top is flat, with pits and five cracks in the middle. There are sometimes prominent stigmas in the center of the cracks, and calyx and fruit stalk at the base. The fruit stalk is square, 3 mm long, brownish green and densely hairy. On the transverse section, the ovary has 5 cells, each cell has 1 ~ 2 pale yellow seeds. Seed oil, hard and fragile. Strong aroma, bitter and slightly spicy taste. It's better to be green and full.

Location: Guizhou, Guangxi, Hunan, Yunnan, Shaanxi, Zhejiang, Sichuan and other places.

In addition to the above varieties, there are immature fruits of Shi Hu and Evodia rutaecarpa, which are also used.

The volatile oils contained in Evodia rutaecarpa fruit include evodiamine, perillene, evolactone, evolactone alcohol and so on. It also contains induced acids. It also contains alkaloids: evodiamine, rutaecarpine, evodiamine, hydroxyevodiamine and evodiamine. After treatment with hydrochloric acid and ethanol, evodiamine was converted into isoevodiamine. It also contains two neutral nitrogen-free substances: evodiamine and evodiamine. It also contains evodiamine.

Dendrobium fruit contains evodiamine, evodiamine, rutaecarpine and hydroxyevodiamine. It also contains unsaturated ketones, temporarily called Shi Hu A, volatile oil, anthocyanins and steroids.

Pharmacological action ① octopus repellent effect

The ethanol extract of Evodia rutaecarpa has significant effect on ascaris suum in vitro. It is also effective for earthworms and leeches.

② Antibacterial effect

Wuzhuyu decoction (100%) has a strong inhibitory effect on Vibrio cholerae (agar groove plate method). 10% aqueous solution has inhibitory effect on Trichophyton floccosum in vitro; The water extraction of 1: 3 has inhibitory effects on 1 1 species of skin fungi, such as Microcystis ordouane.

③ Central function

A large number of Evodia rutaecarpa has an exciting effect on the central nervous system, which can cause visual impairment and hallucinations. The ethanol extract of Evodia rutaecarpa has analgesic effect. The rabbit dental pulp electrokinetic method proved that intravenous injection of 10% ethanol extract 0. 1 ~ 0.5ml/kg had analgesic effect. The analgesic effect of intravenous injection of 0.2 ml is almost the same as that of antipyrine or aminopyrine (1% 2 ml each). But in the cold, it is stronger than these two drugs. 0. 1% isoamyl diamine hydrochloride 0. 1 ~ 0.5 ml/kg also has analgesic effect on rabbits; 1 ~ 2ml/kg can slightly increase the body temperature of rabbits. 0.5 ~ 2.0 ml of 10% Evodia rutaecarpa alcohol extract can also raise the body temperature of rabbits. An alkaloid was proposed from another kind of Evodia rutaecarpa. Evodia plants. Its hydrochloride has sedative and hypnotic effects on mice, but it can lower the body temperature of rats and also resist convulsions caused by camphor.

④ Other functions

0.5 ~ 1.0 ml ethanol extract of Evodia rutaecarpa was injected into rabbits, which caused a short and slight increase in blood pressure, slightly excited breathing and increased carotid blood flow. 0. 1% isoamyl diamine hydrochloride 0.2 ~ 0.5 ml/kg intravenous injection, the blood pressure of rabbits has no obvious change, and the breathing is slightly increased; The effect of 0.02 ~ 0. 1% on isolated frog heart is not obvious, and the perfusion of frog lower limbs is generally not obvious, which expands first and then contracts; For the isolated rabbit intestine, there was a brief excitement at first, and then paralysis; It has an exciting effect on isolated rabbit uterus. The toxicity of evodiamine is low, and the lethal dose to mice is 705 mg/kg by subcutaneous injection and 135 mg/kg by intravenous injection. Components of Evodia rutaecarpa, such as evodiamine, rutaecarpine and rutaecarpine, have similar effects of relieving pain, raising body temperature and slightly affecting respiration and blood pressure. Rutine, the decomposition product of rutaecarpine, has a strong uterine contraction effect. Evodiamine has anti-nosebleed effect on mice.

The alkaloid obtained from Eragrostis is similar to artemisinin, which can enhance the action of adrenaline, improve the excitability of spinal cord reflex, relax the smooth muscle of small intestine and improve the tension of striated muscle, and is similar to ephedrine in some ways.

Processing and roasting Evodia rutaecarpa: decocting Glycyrrhiza uralensis Fisch. Remove the residue to get soup, add clean Evodia rutaecarpa, soak until the soup is completely absorbed, and bake on low heat. (Evodia rutaecarpa per plant 100 kg, Glycyrrhiza uralensis per plant 6 kg 4 Liang)

① Materia Medica Xuan Tong: "Evodia rutaecarpa, salted soup in thick juice, baked in water."

2 "Materia Medica Seeking Truth": "Evodia rutaecarpa Chen Zheliang, soak in bitter juice for later use." Stir-frying coptis chinensis with water to stop vomiting, treating hernia with salt water and treating blood with vinegar. "

Bitter, warm and poisonous in nature.

1 classic: "Xin Wen."

(2) Don't record: "Big fever, small poison."

③ Theory of medicinal properties: "Bitter taste, toxic sexual heat."

Meridian tropism enters the liver and stomach meridians.

① Herbal soup: "Entering the meridians of Taiyin, Shaoyin and Jueyin."

② Description of the nature of drugs processed by Lei Gong: "It enters the liver, spleen, stomach, large intestine meridian and kidney meridian."

It is mainly used for warming the middle warmer, relieving pain, regulating qi and eliminating dampness, and treating vomiting, acid swallowing, stranguria, abdominal distention, menstrual abdominal pain, diarrhea in the fifth watch, hypertension, beriberi, hernia, aphtha, toothache, eczema and impetigo.

① Classic: "Regulating middle energizer, lowering qi, relieving pain, relieving cough, relieving cold and heat, eliminating dampness and removing blood stasis, dispelling cold and dredging collaterals."

② Don't record: "Treat phlegm cold, abdominal cramps, all kinds of cold disappear, middle evil, heart and abdominal pain, and reverse qi to benefit the five internal organs."

(3) Theory of medicinal properties: "Treating heart disease, cold accumulation, qi stagnation under the heart, heartburn; Treat cholera, tendon twitching, stomach cold, vomiting and diarrhea, abdominal pain invincible ninja; " Cure the obstinacy of the whole body, insist on eating cold, and help the large intestine to hold up. "

(4) Supplement to Materia Medica: "If you kill poisonous insects, your teeth will disappear."

⑤ "Rihuazi Herbal Medicine": "Spleen and joints. Treat abdominal pain, kidney qi, beriberi, edema and postpartum hemorrhage. "

⑥ Wang: "Treat chest fullness, obstruction of pharynx and diaphragm, moistening liver and drying spleen."

⑦ "Outline": "Open depression and relieve depression. Treat acid swallowing, phlegm and saliva headache, abdominal pain, hernia, bloody dysentery and aphtha. "

Oral administration and dosage: decoction, 0.5 ~ 2 yuan; I still took the pills and dispersed them. External use: steaming, grinding, dressing or frying.

Yin deficiency and excessive fire should be avoided.

1. Notes on Materia Medica: "I really did it." Evil Danshen, Xiaoshi, chalk, afraid of purple. "

(2) Compendium of Materia Medica: "Diarrhea due to intestinal deficiency is especially taboo."

(3) Outline: "Breathing, burning, dim eyes, aching all over."

(4) "Materia Medica": "Those who vomit and swallow acid are not suitable for stomach fire; Cough due to adverse qi, which is not caused by exogenous wind-cold, cold phlegm blocking water, should not be used; Abdominal pain is not suitable for those with blood deficiency and excessive fire; Red and white diarrhea, due to summer evil into the stomach, rather than wine and food cold, stagnation and scale accumulation should not be used; Small intestinal hernia is not suitable for people who have the first or second onset without suddenly feeling cold evil; Cholera tendon twitching is caused by spleen and stomach weakness and heat, not cold and dampness, and is not suitable for people with gastrointestinal diseases. " All syndromes of yin deficiency and syndromes of internal organs with heat but no cold are legal taboos. "

Prescription 1: Treat kidney qi rising in the throat and accumulating from the abdomen, but you can't spit it out, or you can't breathe for dozens of times: one or two of Evodia rutaecarpa (fried with vinegar), dried tangerine peel and aconite root (peeled). Finally, the batter pills are very big. Take seventy pills per serving of ginger soup. (Ren Cuntang's Classic Prescription)

(2) Treating vinegar, every vinegar is like vinegar: Cornus officinalis. Three glasses of water, fry for seven minutes, and take it immediately. Even if it is strong, it is stronger. ("Ministry of War Hand Sacrifice")

③ For those who have swallowed acid and stomach deficiency and cold, Evodia rutaecarpa (soaked in soup for seven times and baked) and dried ginger (processed) are equally divided. Finally, the soup costs one yuan. (Sheng Huifang)

④ Treatment of liver fire: Coptidis Rhizoma and Evodia rutaecarpa, one or two or half two. The top is the end, water pill or steamed cake pill. Take fifty pills in white soup. (Zuo Jin Pill, Hui Ling Pill in Danxi Heart Method)

⑤ Patients with vomiting, chest tightness, retching, salivation and headache: one liter of Evodia rutaecarpa, three ounces of ginseng, six ounces of ginger and twelve jujubes. Take four flavors, five liters of water, three liters of boiling water, warm clothes seven times, three times a day. ("synopsis of the golden chamber" Wuzhuyu decoction)

⑥ Curing head wind: Evodia rutaecarpa three liters. Five liters of water, three liters of boiling water and cotton wool. Root. (Dry Golden Wings)

⑦ Treat excessive phlegm, headache, cold back, spitting sour juice, lying on the pillow for several days without eating, once every ten days: Evodia rutaecarpa (soaked in soup for seven times), Poria. Finally, honey pills will make a good child. Fifty capsules per hot water, (Zhu Folk Prescription Collection)

⑧ There are many elderly people who have been treating spleen diarrhea for many years, which is called water and soil assimilation: Evodia rutaecarpa San Qian. Soak, decoct, add a little salt and take orally. Cornus officinalis can warm bladder, smooth waterway and self-solidify large intestine. Although other drugs are hot, they cannot be decomposed into turbidity. (Ren Cuntang's Classic Prescription)

⑨ Treating spleen with dampness leads to excessive diarrhea, delayed rice grains and tingling in navel and abdomen; Malnutrition and diarrhea in children can also be treated: Coptidis Rhizoma (removing beard), Evodia rutaecarpa (removing stem and frying) and Radix Paeoniae Alba. The top is fine powder, and the batter is pills, such as buttonwood. Take 20 capsules each time, and take them with thick fried rice three times a day. ("Bureau Prescription" Wuji Pill)

Indications for beriberi, lethargy and abdominal distension: six liters of Evodia rutaecarpa and two papaya (cut). To serve two flavors, take three liters of water in a bucket, boil three liters, and serve three servings. If you walk ten miles, eat, vomit, sweat, benefit, or feel hot and stuffy, that is. (Qian Jinfang, Su Changshi, Cornus Soup)

⑾ To treat beriberi pain, if people feel rheumatism, painful feet and swollen tendons, they should take it: seven areca nuts, one or two pericarpium Citri Reticulatae, one or two papaya, one Evodia San Qian, one perilla leaf, half a platycodon grandiflorum (without reed) and half a ginger (with peel). Fine-cut, decocted in water, served in three or five servings at five o'clock the next day, just cooled. There are also some warm clothes in winter. ("Standard of Syndrome Treatment" Ji Ming San)

⑿ In recent years, it has been used to treat small intestinal hernia, such as traumatic pain, tenderness under the umbilicus, which causes the external kidney to be stuffy, swollen and hard, and the external kidney to grow day by day, and the external kidney is wet and itchy, resulting in sores: Evodia rutaecarpa (removing branches) 1 kg (soaked in wine for four times, soaked in vinegar for four times, soaked in soup for four times, soaked in urine for four times, soaked for one night each, and dried together), Alisma orientale. The top is fine powder, and the batter balls cooked with wine are as big as buttonwood. Take 50 capsules each time and swallow them with salt soup or wine before eating. ("Bureau" kills Dan)

(13) Treatment of renal contraction in children (caused by neonatal cold): Evodia rutaecarpa, sulfur 50/50. After grinding, it is coated with garlic and still smoked with Fructus Cnidii. (Sheng Huifang)

[14] Treatment of aphtha and malnutrition: Cornus officinalis powder, vinegar applied to the heart. It also treats sore throats. ("lakeside collection simplified formula")

⒂ Treatment of toothache: Cornus officinalis is decocted with wine and gargled. ("Dietotherapy Materia Medica")

⒃ Treatment of eczema: one or two pieces of fried Evodia rutaecarpa, seven pieces of cuttlefish bone and two pieces of sulfur. * * * Grind into fine powder for use. Dry powder is sprinkled on patients with eczema exudation; If there is no exudate, dissolve it with castor oil or pig's plate oil, once every other day, and wrap it with gauze after application. (Selected Works of Dermatology in Full Exhibition)

⒄ Treatment of wet itchy sores under the yin: Evodia rutaecarpa 1 liter, 3 liters of water, boiled for three or five times, to remove my sore. Treat all kinds of sores. (Ancient and modern folk prescription records)

⒅ Stroke (mouth tilted, unable to speak). Use one liter of Cornus officinalis, three liters of ginger and five procedures of sake to fry for several times. After cooling, take half a liter each time. Take it three times a day. A slight sweat will heal you.

Pet-name ruby itchy all over. Use one liter of Cornus officinalis, add five liters of wine, boil to one and a half liters, scrub with warm water, and stop itching.

It is very cold in winter and the moon. Decoct the soup with Evodia rutaecarpa with five cents, and sweat as the degree.

(2 1) Vomiting, chest tightness and headache. Take one liter of Cornus officinalis, twenty jujubes, one or two ginger and one or two ginseng, and add five liters of water to make three liters. Take it seven times each time, twice a day. This recipe is called "Evodia rutaecarpa soup".

(22) Cold pain in the heart. Evodia rutaecarpa is boiled with three liters of wine and taken in three times.

(23) small intestinal hernia (falling pain, swelling and pain of testicles, wet itching). Use a catty of Evodia rutaecarpa (stem removed) and divide it into four parts. Soak in wine, vinegar, boiled water and toilet. After a night, take it out and bake it, add two ounces of Alisma orientale, grind it into powder, and adjust it to the size of meatballs with wine and powder. Take 50 capsules each time, hollow clothes, salt soup or wine. This prescription is called "Despair Dan" and also called "Stars Pill".

(24) A woman is cold and not pregnant for a long time. Use Evodia rutaecarpa 1 l and Zanthoxylum bungeanum 1 l, grind into powder, and add honey to make balls as big as marbles. The wrapped cotton meat is included in * * * so that the uterus can be conceived.

(25) Stomach qi deficiency and cold, sour water in mouth. Soak Evodia rutaecarpa in boiling water for seven times, take it out and bake it, and add dried ginger (cannon) to powder. Every time a fee is charged, hot soup is served once.

(26) Turn the tendons into the abdomen. Stir-fry two ounces of Cornus officinalis, add two bowls of wine, stir-fry into a bowl, and take it twice. Diarrhea is the treatment.

The old man has been leaking water for many years. Soak Evodia rutaecarpa in San Qian, take it out, add water and a little salt before taking it.

(28) Red and white dysentery (damp-heat of spleen and stomach, diarrhea and abdominal pain, indigestion after eating rice). Parching one or two of Evodia rutaecarpa, Coptidis Rhizoma and Radix Paeoniae Alba, adding steamed cakes, and making into balls, the size of which is like five pills. Take twenty or thirty capsules each time and send rice soup. This recipe is called "Wuji Pill". Another recipe: Chuanhuanglian No.2 Canyon and Evodia rutaecarpa (Tang Qin seven times) are fried together, respectively ground into powder, and made into balls with corn rice. If it is as big as five sons, store it for later use. Take thirty pills at a time. Dysentery, take Huanglian pill with licorice soup; White dysentery, take dogwood pills with dried ginger soup; Red and white dysentery, take 15 pills each, and send rice soup. This prescription is called "Rouwan". Another prescription: use two ounces of Evodia rutaecarpa and two ounces of Coptis chinensis, stir-fry together, each at the end. Make balls with paraquat, rice and coptis root; Add 20% white peony root powder, rice and Cornus officinalis to make balls, each ball is as big as a quintuple, and store for later use. Take fifty pills at a time. Red dysentery, ebony soup with even double pills; White dysentery, take Zhu Shaowan with rice soup; Red and white dysentery, 25 capsules each. This prescription is called "Erse Pill".

(29) Abdominal mass. Mash with 1 liter of Cornus officinalis, cook with wine, take it out of a soft cloth, press it, cool it, fry it, and then scald it. If the blocks move, the ironing will also move until the accumulated blocks are eliminated.

(30) toothache. Wash with Cornus officinalis decoction.

(3 1) rubella of all ages. Wipe it with Cornus officinalis fried wine.

(32) carbuncle back. Pour one liter of Evodia rutaecarpa into the powder, add bitter wine and apply it to the affected area.

(33) Strange diseases of cold and heat (cold and heat continue, and after a few days, the limbs are as hard as stones, and there is a copper sound when knocking, and it is getting thinner and thinner). Divide Cornus officinalis and Radix Aucklandiae into equal parts, decoct, and stimulate oral administration.

The effect of Evodia rutaecarpa is to warm the middle warmer, dispel cold, reduce qi and relieve depression. In recent years, it has been used in clinical practice, and this product is also used to treat pinworm disease. Clinical practice shows that Evodia rutaecarpa has obvious analgesic and antiemetic effects.

Clinical application ① Treatment of hypertension

Grind Evodia rutaecarpa into powder, take 0.6 ~ 1 2 each time, and apply it to the soles of feet with vinegar (preferably before going to bed, wrapped in cloth). After applying 12 ~ 24 hours, blood pressure began to drop and symptoms were relieved. Apply 1 time for light patients, and 2 ~ 3 times for heavy patients will show the effect of lowering blood pressure.

② Treatment of dyspepsia.

Take 2.5 ~ 3g of Evodia rutaecarpa powder, mix it with 5 ~ 6ml of vinegar, heat it to about 40℃, spread it on two layers of square gauze (about 0.5cm thick), and take 4 twists. Stick it on the navel and fix it with adhesive tape. 12 hour replacement 1 time. After 20 cases were treated, 18 cases were cured, 1 case was improved and 1 case was ineffective. Preliminary observation shows that this method has the functions of regulating gastrointestinal function, warming interior and dispelling cold, relieving pain and helping digestion. It has good curative effect on diarrhea caused by gastric dysfunction, and has synergistic effect with antibiotics on diarrhea caused by bacterial infection.

③ Treating eczema and neurodermatitis.

Grinding Evodia rutaecarpa into powder, and mixing with vaseline into 30% (A) and 20% (B) ointment; Then take 30% Evodia rutaecarpa ointment and the same amount of zinc oxide ointment and mix them evenly to make compound Evodia rutaecarpa ointment (type C). For subacute and general chronic eczema, as well as subacute or early scrotal eczema, use ointment B; Chronic scrotal eczema for many years, using ointment; Infantile eczema is treated with ointment. Topical medication twice a day. For neurodermatitis, apply ointment A first, and then cooperate with a hot hair dryer, 1 time, once a day for 20 minutes, and then stick it with a piece of adhesive tape slightly larger than the lesion. According to the observation of 82 cases of eczema and neurodermatitis, the curative effect on early eczema and subacute eczema is good, and the cure time is short, 3 days; For general chronic eczema, the shortest cure time is 10 day; It is ineffective for chronic eczema with lichenoid transformation for many years; Infantile eczema 1 1 case, except for 2 cases that were ineffective, the rest were clinically cured within 7 ~ 15 days. The initial effect of scrotal eczema is obvious, but it is ineffective for those who have been ill for many years and are close to lichenoid transformation. 19 cases of neurodermatitis, all of them are mild localized patients, and the curative effect of hot hair dryer is more obvious than that of simple application. 10% Evodia rutaecarpa ointment was applied locally, and then fumigated with moxa sticks for 20 minutes to treat 4 cases of localized neurodermatitis/kloc-0. Results 4 cases were cured, 7 cases were markedly effective and 3 cases were improved. Cured cases are generally treated for 4 ~ 6 times. The method has obvious antipruritic effect.

④ Treating yellow sores.

Evodia rutaecarpa was ground into 10% ointment with vaseline, and applied locally, 1 ~ 2 times a day. Wash the affected area with warm water before rubbing the medicine: 12 cases were treated, and generally recovered for 4 ~ 6 times.

⑤ Treat oral ulcer.

Mashing Evodia rutaecarpa, sieving, mixing the fine powder with proper amount of good vinegar into paste, applying it on gauze, applying it on bilateral Yongquan points, and taking it off after 24 hours. Dosage: 1 0.5 ~ 2 yuan,12 ~ 3 yuan, 6 ~13 ~ 4 yuan,14 ~ 5 yuan. 256 cases were treated and 247 cases were cured. Generally 1 application is effective.

Remind you: Evodia rutaecarpa, a Chinese herbal medicine, comes from the Internet. Please follow the doctor's advice before use.