cause of a disease
Alcohol allergy is actually an external skin allergic reaction caused by the lack of acetaldehyde invertase in the body. After alcohol is converted into acetaldehyde in the body, it can't be converted into acetic acid because of the lack of acetaldehyde invertase in the body, which causes acetaldehyde poisoning and people will have various symptoms of alcohol allergy. The two necessary conditions of alcohol allergy are allergic constitution and alcohol, and most allergic constitutions lack acetaldehyde invertase. People who drink a lot of alcohol have a lot of this enzyme in their bodies, which can be quickly transformed without poisoning symptoms, so they will not get drunk. Most people who are allergic to alcohol are allergic. Then once the allergic constitution comes into contact with alcohol, there will be a variety of alcohol allergy symptoms.
pathogenesis
People with allergic constitution contain an immunoglobulin, and alcohol allergens combine with it to make mast cells threshold and release histamine, which can increase the capillary permeability of the body and cause mucosal edema, increased gland secretion and itching. Therefore, people who are allergic to alcohol will have symptoms of alcohol allergy, such as itching all over the body, red papules and erythema all over or partially.
Treatment of alcohol allergy
Alcohol contains low molecular weight substances (such as butane and methanol), acetaldehyde, esters, histamine, phenol, tannic acid, iron, lead and cobalt. Alcohol is an inhibitor of the central nervous system, which can reduce the activity of neurons. 2% (low blood alcohol concentration) to about 10% (high blood alcohol concentration) ethanol is directly excreted through the lungs, urine and sweat, but most of it is metabolized by acetaldehyde in the liver. The above route eventually produces acetaldehyde. People with allergic constitution are allergic to acetaldehyde, and the high or low concentration will be reflected in people with alcohol allergy. Higher concentrations of alcohol accumulated in the liver, brain or other tissues of the body can cause organ damage.
Symptoms of alcohol allergy can be divided into two types: rapid onset and delayed onset.
The symptoms of alcohol allergy are short and severe. Besides being red and itchy, there is also dyspnea caused by laryngeal edema. If the rescue is not timely, it can lead to death, and there are few cases of rapid onset in clinic.
There are many delayed cases of alcohol allergy, which are generally manifested as itching all over the body after drinking, and red papules and erythema appear all over or locally for one or two days.
The symptoms of alcohol allergy are itchy back, red beans, fever, or erythema, which is unbearable. The reason for alcohol allergy is that these people are allergic. Alcohol is an allergen, and contact with allergens can cause allergies.
Other common clinical manifestations of alcohol allergy include skin symptoms, respiratory symptoms and digestive tract symptoms. Such as skin itching, eczema, urticaria, dizziness, nausea, vomiting, diarrhea, and even a few people will have anaphylactic shock. The latest research method, when the body has allergic reaction, will involve the heart, leading to vasodilation, rapid heartbeat, low blood pressure, increased burden on the heart, and the prominent symptom is arrhythmia.