Fundamentally speaking, chloasma is caused by endocrine disorders and the deposition of metabolic wastes on the face. Coupled with the long sunshine time, it is easy to cause melanin deposition, which is manifested as the generation and deepening of chloasma.
How to get rid of chloasma?
In order to fundamentally eliminate chloasma, we must start with regulating endocrine.
There are many reasons for endocrine disorders, such as poor mood and feelings, abnormal release of liver qi, qi stagnation and blood stasis. , coupled with monthly holidays, leading to loss of qi and blood, but also easy to cause endocrine disorders; Insomnia; Irregular diet; Many factors in life, such as fatigue, can also cause endocrine disorders.
In view of these reasons, the most effective way is to take some pure Chinese medicine health care products to regulate endocrine, and regulate endocrine by removing blood stasis and dredging collaterals and improving circulation, so as to eliminate stagnation in the body and restore human function to a good physiological state.
Of course, we should also develop good living habits and maintain a good mood; Eat more fruits scientifically, mainly fresh vegetables and high-protein and low-fat foods. In addition, we should pay attention to cooling down, drink more boiled water and replenish water in the body.
Women should know how to maintain themselves, adjust their endocrine, stay away from the troubles of breast lumps, uterine fibroids and chloasma, and start from usual. Eating some symptomatic Chinese medicine health care products can stay away from pain. You can try some antioxidant health foods, for example, vitamin E, or β -carotene soft capsules, lycopene, aloe capsules, which can be improved, but don't expect immediate results, because your chloasma is not an organic disease, so don't expect drugs to get rid of it, but gradually adjust it to get better. In addition, keep the stool unobstructed!
Avoid sun exposure, if there is a cause, try to remove the cause. Chloasma caused by birth control pills should be stopped, but it may not disappear in a short time.
1. systemic therapy, taking a large amount of vitamin c orally, 1 ~ 3g a day, or taking vitamin c2g intravenously. Vitamin C can reduce the deep oxidized pigment to the shallow one, and reduce dopaquinone to dopa, thus inhibiting the formation of melanin.
2. The combination of local treatment, local external use and oral administration has good curative effect.
(1) bleach
1) hydroquinone preparation 3% ~ 5% hydroquinone cream, 2.6 tert-butyl phenol cream, 10% ~ 20% hydroquinone monophenyl ether cream and 3% hydroquinone monopropionate are effective for external use. Hydroquinone mainly blocks the reaction process of tyrosine to dopa catalyzed by tyrosinase, which reduces the production of melanin, that is, prevents the oxidation of tyrosine to dihydroxyphenylalanine (do-pa), and effectively prevents the production of melanin. Hydroquinone cream: Don't rub and damage the normal skin nearby, and don't use it too much, so as not to make the skin mottled and uneven. Very few patients are allergic to dermatitis. 20% hydroquinone monobenzyl ether emulsion or ointment can be used, which can be converted into hydroquinone in the skin with the same effect. It may be effective for stubborn cases, and it should be noted that it is easy to cause allergies, uneven decoloration or permanent decoloration.
2) Put the tretinoin preparation of 0. 1% tretinoin, 5% hydroquinone and 0. 1% dexamethasone into hydrophilic ointment or mix it with the same amount of propylene glycol alcohol solution (the solution must be freshly prepared). For external use twice a day, erythema stimulation often appears at the initial stage of treatment, and the pigment can be significantly reduced after about 4 ~ 6 weeks.
3) 2 ~ 5% hydrogen peroxide external rubbing can also be decolored.
(2) When sunscreen is used to treat chloasma, sunscreen is combined to enhance the curative effect. Sunscreen can resist ultraviolet and visible light, thus protecting the skin from harm and preventing pigmentation.
1) p-aminobenzoic acid (paba) easily absorbs UVB (280 ~ 320 nm). The 50% ~ 60% alcohol solution of 5%paba is the most effective and can cause allergies. It has been applied in clinic.
2) Phenyl salicylate (also known as salor) is often made into 10% cream for external use.
3) Titanium dioxide 5% titanium dioxide cream is used externally, which has the function of sunscreen spots.
(3) Anti-skin aging agent
1) 1% vitamin e cream can inhibit lipid peroxidation caused by free radicals and prevent skin aging and pigmentation.
2) 15% seabuckthorn emulsion is made of mixed vegetable oil extracted from seabuckthorn fruit and emulsion matrix. Seabuckthorn contains vitamins C, E, β-carotene and various amino acids, and has anti-aging and anti-pigmentation effects.
3. There are many ways to treat TCM with different curative effects. Different patients should be treated according to syndrome differentiation. Liver depression and qi stagnation can be treated by soothing the liver, regulating qi and promoting blood circulation, and the prescriptions include Xiaoyao powder and Chaihu Shugan powder. The spleen deficiency type is modified by Erchen Decoction and Sijunzi Decoction. Kidney deficiency type is modified with Liuwei Dihuang Pill.
Patients with chloasma are mostly kidney yin deficiency, which can be treated mainly with Qiju Dihuang plus Huangbai Chenpi Decoction. Promoting blood circulation and removing blood stasis, soothing the liver and regulating qi, using Xuefu Zhuyu decoction and Ren Tao Siwu decoction.
etiology
Its etiology is not clear, and it is generally considered to be related to the change of endocrine function. Found in pregnant women or people taking oral contraceptives and other factors. Women's chloasma (chloasma) begins in the third to fifth month of pregnancy, and the postpartum pigmentation gradually disappears. Facial pigmentation may be due to the joint action of estrogen and progesterone, which stimulates melanocytes, while progesterone promotes the transport and diffusion of melanosome, increases the production of melanin and promotes pigmentation.
It can also be seen in chronic gastrointestinal diseases, liver diseases, tuberculosis, cancer, malignant lymphoma and chronic alcoholism. Long-term use of phenytoin sodium, hibernating spirit, birth control pills and other drugs will cause chloasma. In addition, intense sun exposure and cosmetic smearing can also induce chloasma. Chloasma is also found in unmarried, non-pregnant normal women or men, and its reason is unknown.
pathological change
Excessive precipitation of epidermal pigment and more pigment in dermal melanocytes. There is a small amount of lymphocyte infiltration around dermal blood vessels and hair follicles.
clinical picture
Skin lesions are light brown or yellowish brown spots with clear boundaries and irregular shapes, which are symmetrically distributed around the eyes, forehead, eyebrow arch, nose, cheeks, lips and mouth, and there are no conscious symptoms and general discomfort.