Many friends have the problem of hyperlipidemia, and many friends often associate lowering blood lipids with removing vascular garbage and softening blood vessels. In fact, the problem of hyperlipidemia and dyslipidemia is the problem of blood lipid metabolism in human body. Although it can be compared to "removing vascular garbage", in fact, there are lipid deposits in blood vessels, which are often difficult to remove. As for softening blood vessels, it is even more impossible. For arteriosclerosis caused by dyslipidemia, re-softening blood vessels is just a good wish. What we can do is to control blood lipids, slow down the process of arteriosclerosis and reduce the risk of cardiovascular diseases caused by arteriosclerosis. What drugs can reduce blood fat, which has good curative effect and effect on controlling blood fat? Today, I will give you a brief introduction-statins have such and such views on statins, and even a persistent netizen left me a message and showed me a video of an association in Europe, saying that statins can only reduce the cardiovascular risk of 1%. However, among the current hypolipidemic drugs, the basic status and exact efficacy of statins have not been shaken by other drugs. Statins can effectively reduce the level of low density lipoprotein cholesterol and total cholesterol by inhibiting the synthesis of cholesterol in liver. At the same time, statins can also help reduce triglycerides and improve high-density lipoprotein cholesterol, which can not only effectively control blood lipids, but also be important drugs for primary and secondary prevention of cardiovascular diseases. Of course, as an important drug for primary and secondary prevention of cardiovascular diseases, it is also inseparable from its clear lowering effect on low-density lipoprotein cholesterol. When taking statins, we should pay attention to the effectiveness of the drugs. For patients with cardiovascular diseases, it is suggested that the level of low-density lipoprotein cholesterol should be controlled below 1.8 or even lower, while for friends who have no cardiovascular diseases but are at high risk, the level of low-density lipoprotein cholesterol should at least be reduced below 2.6. At the same time, taking statins should also pay attention to safety. Ethnic differences lead to a higher probability of muscle pain, abnormal liver function and other problems when people of yellow race in China take statins with the same drug strength. Therefore, on the premise of controlling blood lipids to reach the standard, statins with low lipid-lowering intensity should be selected as far as possible, with low lipid-lowering intensity and low incidence of side effects. When the body is intolerant of statins, resulting in the increase of transaminase by more than 3 times and creatine kinase by more than 5 times, statins should be stopped or other types of statins should be taken. Ezetimibe is another drug widely used in the field of reducing blood lipid in recent years. It is a drug to reduce blood lipid by inhibiting the intestinal absorption of cholesterol. The lipid-lowering intensity of ezetimibe is lower than that of statins, but the lipid-lowering effect and cardiovascular disease prevention effect of statins combined with ezetimibe are often stronger than that of simply doubling the dosage of statins. Therefore, for hyperlipidemia patients who can't tolerate high-dose statins, if the blood lipid is not up to standard, ezetimibe can be combined to reduce blood lipid. Besides ezetimibe, there are some other lipid-lowering drugs worthy of attention. Probucol is a strong antioxidant, which can enhance the clearance of LDL cholesterol by affecting the metabolism of LDL. At the same time, clinical research also found that this drug has antioxidant effect and can delay the process of arteriosclerosis, but it should be noted that it not only reduces low-density lipoprotein cholesterol, but also reduces high-density lipoprotein cholesterol (good cholesterol) to some extent. In addition, besides probucol, there are some drugs that can be used to regulate the level of low-density lipoprotein cholesterol, such as cholic acid chelating agent Coleenamine, Coletipol, Colevillein and so on. These drugs can prevent the reabsorption of cholesterol in bile acids in the intestine, and the combination with statins can improve the lipid-lowering effect, but generally these drugs are not suitable for patients with abnormal β -lipoprotein or triglyceride over 4.5. There are also some Chinese patent medicines that can regulate blood lipids. Xuezhikang, Zhibitai and other Chinese patent medicines all contain traditional Chinese medicine monascus, and monascus also has a certain blood lipid lowering effect. It is found that the main lipid-lowering component in monascus is lovastatin with natural structure, so the possible adverse reactions of statins also exist in these Chinese patent medicines. However, due to the low concentration of statins, the lipid-lowering effect is weaker than statins, and the incidence of adverse reactions is low. Some patients have friends who take high triglyceride drugs. The levels of total cholesterol and low-density lipoprotein cholesterol in blood lipid indexes are normal, but there are cases of high triglycerides. The increase of triglyceride will lead to the increase of blood viscosity, making it easier for blood lipids to deposit on the blood vessel wall. At the same time, this serious increase in blood lipid level will also lead to an increase in the risk of acute pancreatitis. Therefore, whether for cardiovascular health or reducing the risk of pancreatitis, high triglyceride is also an index that needs to be controlled. Usually for people with high triglycerides who have habits such as high-fat diet, no exercise, staying up late, drinking spirits, etc. Get rid of these bad habits and triglycerides will be greatly improved. However, if the triglyceride level cannot be effectively reduced through life intervention, drug treatment should also be considered to control triglyceride. Statins have limited effect on improving and controlling triglycerides. It is usually recommended to use fibrates to regulate and control triglycerides in clinic. Patients with hypertriglyceridemia can use fenofibrate, bezafib, gemfibrozil and other drugs. These drugs also have the risk of adverse reactions, such as abnormal liver function and muscle pain. If combined with statins, more attention should be paid to it. In addition to fibrates, high-purity fish oil preparation is also one of the drugs to reduce triglyceride levels. Generally, it is difficult for health care products on the market to reach the level that can reduce the purity of triglycerides. Only high-purity drug brand products can have a certain effect of reducing triglycerides. Taking such drugs should pay attention to the risk of adverse reactions in the digestive tract, and patients are prone to bleeding occasionally. Therefore, although high-purity fish oil is relatively safe, we should also pay attention to the risks of taking drugs. High-dose nicotinic acid drugs are also optional drugs to regulate triglycerides. Nicotinic acid is actually vitamin B3, which is a B vitamin. High-dose nicotinic acid preparation can effectively reduce the level of blood lipid, and the regulation of triglyceride is more obvious. However, taking large doses of nicotinic acid will cause gastrointestinal discomfort, elevated uric acid, elevated blood sugar, liver damage and other adverse reactions. , and now generally not used. If applied, the safety of medication should be guaranteed. # Breeze Project # Disclaimer: The above content comes from the Internet, and the copyright belongs to the original author. If there is any infringement of your original copyright, please let us know and we will delete the relevant content as soon as possible.