From the perspective of traditional Chinese medicine, seafood is generally wet and cold food, and excessive intake may make the human body moist and affect health. Seafood generally contains a lot of elements such as zinc and iodine. Long-term intake of these substances in large quantities may lead to deposition beyond the daily physiological needs, which may lead to related diseases due to excessive intake. Excessive intake of zinc and iodine is harmful.

Patients with gout, arthritis and hyperuricemia should eat less seafood. Because of the high content of purine in seafood, patients are prone to form uric acid crystals in the body after eating, which aggravates their illness. In addition, patients with hyperthyroidism should eat less seafood, because the iodine content in seafood is high, and too high iodine content will aggravate the condition.