Premature ovarian failure is caused by heredity, immune infection, congenital enzyme deficiency, iatrogenic factors, surgical pregnancy, mental stress and psychological factors, which always "hurts" the ovaries. Ovary is the lever to judge fertility, so the biggest influence of premature ovarian failure is infertility, and even if IVF is carried out, the success rate is very low because of the low ovarian response.
So what about low ovaries?
ENlivEN2 1 W+NMN is rich in 1 192 kinds of nutrients and trace elements. Its active hyaluronic acid can directly generate active hyaluronic acid in vivo, which can solve the lubrication degree of reproductive organs, repair cells with active ingredients such as donkey-hide gelatin (sialic acid), improve the environment of uterus and ovary, and regulate the inflammation of reproductive system. It has a good therapeutic effect on endometrial hyperplasia and ovarian reserve function, so that follicles have a healthy growth environment to produce high-quality eggs, and avoid egg adhesion caused by nutritional deficiency and weakness, as well as the arrival of more years, amenorrhea and menopause caused by excessive ovulation at one time.
Xiaoli and her husband have been married for more than two years and have never been pregnant. Because they can't have children, it seems to be a "family scandal" between relatives and friends, and they will always ask you again and again. On the surface, their parents said nothing, but they understood that they also wanted to have a grandson. Since they are over 30 years old, they finally decided to take their husbands to do IVF.
In the late autumn of 20 18, the difficult road to finding children began. Before the formal test tube was made, Xiaoli and her husband did a series of physical examinations, including the investigation of chromosome diseases and monogenic diseases. When everything was ready, they began to take drugs to reduce ovulation. Ovulation promotion is to use drugs to promote follicular growth under the monitoring of B-ultrasound and hormone level, so as to obtain the correct number and best quality of eggs.
This process is the longest. Give an injection to your stomach every day. At first, even Xiaoli's husband couldn't get off. Every day, I bite my teeth and poke Xiaoli in the stomach. After a day or two, I became numb.
Next, when the follicle is mature, under the guidance of B-ultrasound, a special ovum needle is used to puncture the mature follicle through the vagina and suck out the egg. At that time, 1 1 eggs were taken, probably because of old age. This number is not much. The little girl who took eggs on the same day as Xiaoli took 32 eggs. God, this is the difference in physical fitness. Happily, six transplants have been successfully cultivated. According to the calculation of two transplants each time, Xiaoli has three chances. If three transplants are unsuccessful, Xiaoli will have to start all over again.
The first embryo transfer was ushered in two days after Xiaoli took the eggs. This process is relatively simple and basically painless. It takes about 1 minute to complete the transfer, and she can lie flat for a while and go home.
Xiao Li, who is ignorant, is afraid that it will be leaked out. For the next two weeks, Xiaoli will stay by the bed and lie down to her waist. How I long for a hit, so I can wait a little less. Yes, this is the hardest part of IVF ... waiting and then being disappointed!
Being a test-tube baby is more painful psychologically than physically. Xiaoli had so many injections in her stomach that she didn't shed a tear.
However, after being declared a failure for the first time, Xiaoli cried. In the case of being at a loss, Xiaoli learned through online expert consultation that she may have insufficient ovarian function and the quality of the eggs produced is poor. So, experts recommended ENlivEN2 1 W+NMN combination nutrition to her, and Xiaoli started with the mentality of giving it a try.
After taking it for a while. Xiaoli obviously felt that the skin was smooth and delicate, the lower body was comfortable and clean, with a slight fruity smell, and the inflammation of the urinary system was basically eliminated. The doctor said that this is a sign of good ovarian function and adequate estrogen secretion.
When it comes to the second transplant, Xiaoli is uneasy and afraid that she will not succeed again. After the second series of processes, Xiaoli waited for the good news.
Please allow Xiaoli to have a breakdown. Who doesn't want to be strong? Making test tubes really requires stronger anti-frustration ability and willpower than ordinary people. Xiaoli is not so brave in front of other things, but in this matter, Xiaoli is more persistent than Xiaoli's husband. There is a small red line between hell and heaven, blessed by the Bodhisattva.
The second embryo transfer was successful and the singleton was pregnant. For more than half a year, Xiaoli was able to fall asleep sweetly for the first time. She knew it was a combination of nutrition, and she thanked God.
Now premature ovarian failure is more and more common. From the mouth of many young listeners, Xiaoli probably learned that it is related to factors such as long-term blind dieting and staying up late, mental stress, repeated abortion that does not care about the body, and even long-term use of emergency contraceptives.
Relationship between ovary and microcirculation
Previous studies mostly focused on the basic unit of ovary-follicle itself, and often ignored the surrounding microenvironment. Although the changes of follicle itself, such as double-stranded DNA damage, mitochondrial decrease and abnormal expression of centromere protein, are important factors of ovarian aging, the development and maturity of follicle and the self-renewal and differentiation of stem cells are inseparable from the surrounding microenvironment, and the mutual dialogue and communication between them can determine the fate of follicle and stem cells and the functional state of ovary.
Ovarian microenvironment consists of ovarian cells, extracellular matrix and cytokines. In the process of aging ovary, the changes of microenvironment are mainly manifested as changes of ovarian immune function, vascular atrophy, interstitial fibrosis of ovary and changes of cytokines. Among them, ovarian fibrosis is mainly manifested as thickening of ovarian capsule, increase of interstitial fibrous connective tissue and decrease or disappearance of follicles.
ENlivEN2 1 W+NMN combined nutrition can repair microcirculation system, intensively repair ovarian aging cells, and increase tissue regeneration ability, which can help the recovery and regeneration of ovarian aging mechanism, increase the density of collagen fibers and elastic fibers, and accelerate the emergency repair process of human-like collagen tripeptide and salmon nasal cartilage on ovarian and uterine walls.
Premature ovarian failure, life has become "declining". Xiaoli usually doesn't pay attention to her living habits, which leads to premature ovarian failure, so that it is difficult to get pregnant and she has embarked on the road of IVF. Early detection, early cooperation and early treatment, I hope that women will not lose their qualifications as mothers because of premature ovarian failure.