Judging from the current scientific research situation, heart transplant recipients will not have any memory of the donor heart, because people's emotions and memory centers are in the brain. The simplest example is that if a patient with heart failure is waiting for a donor heart, there is no special emotional change in the process of using artificial heart to assist circulation to maintain life. Usually, because of the improvement of blood pressure and organ perfusion, people's mental state will be better than that of heart failure. Explain that the heart does not affect people's spirit and memory.

However, in some cases, the personality of patients will change after heart transplantation, which may be related to the side effects of anti-rejection drugs, brain reperfusion injury after cardiopulmonary bypass, hallucinations caused by sedatives and analgesics, and mental and psychological disorders caused by long-term stay in ICU. It cannot be said that the change is entirely due to the specific embodiment of the patient's habits in the transplant.

Although China's traditional medicine thinks that the mind is the master of gods and the brain is the master of memory, we usually talk about memorizing by heart rather than brain. In foreign English, idioms that are studied and recited hard are also studied by heart rather than by brain. However, this is only because people found in early life practice that once the heart stops beating, there will be unconscious and mental activities.