Introduction: Paishi decoction is a kind of traditional Chinese medicine decoction, which is tolerant and safe to use, and has obvious dissolution effect on gallstones in vitro. The treatment of gallstones with traditional Chinese medicine decoction is analyzed below. Welcome to read!
The composition principle of traditional Chinese medicine decoction is based on the theory of syndrome differentiation and treatment of traditional Chinese medicine, combined with long-term clinical experience in treating gallstones, and based on screening ancient and modern prescriptions. Traditional Chinese medicine Paishi decoction has the effects of clearing away heat, promoting diuresis, promoting gallbladder and expelling stones, and is an ideal drug for treating gallstones.
Gallbladder stones; Traditional Chinese medicine decoction
Cholelithiasis is one of the common and frequently-occurring diseases in China.
The incidence of gallstones in the natural population is about 10%, of which gallstones account for about 50% of all gallstones, and the incidence is on the rise, which is a serious health-threatening disease. In recent decades, traditional Chinese medicine (TCM) has been accepted by the majority of patients for its definite curative effect, low price and few toxic and side effects, which shows the advantages of TCM in treating cholelithiasis.
Clinical manifestations of 1
1. 1 biliary colic
This is the most typical manifestation of gallbladder stones. The degree of colic varies from person to person, mostly after eating greasy food or at night. It shows severe pain in the right upper abdomen, which may involve the right shoulder and back. During the examination, the right upper abdomen was tender, the muscles were tense, and sometimes the swollen gallbladder could be touched, with Murphy's sign (+). The attack may be accompanied by nausea and vomiting. Gallbladder colic occurs because stones are embedded in the neck of gallbladder, which leads to the increase of pressure in the capsule. In addition, bile acid stimulates gallbladder mucosa, causing inflammation, edema, congestion and exudation, which leads to acute cholecystitis.
1.2 Gastrointestinal symptoms
Often manifested as fullness in the right upper abdomen, dull pain and discomfort, tiredness, belching and indigestion, often induced and aggravated by eating greasy food.
2 Etiology and pathogenesis
The main causes of this disease are emotional disorder, improper diet or insect accumulation, which leads to gallbladder failure, dampness stagnation, heat accumulation, long-term accumulation of damp heat, and gall bladder and stones.
3 General situation of treatment
3. 1 handling principle
Promoting blood circulation, removing blood stasis, clearing heat and promoting diuresis, soothing the liver and promoting gallbladder function, etc.
3. 1. 1 Effect of traditional Chinese medicine on biliary tract function
Traditional Chinese medicine can relax Oddi sphincter and promote gallbladder contraction. Chen Yin Daodao Decoction can relax Oddi sphincter, especially for spasmodic sphincter. Mume and hawthorn have the function of promoting gallbladder contraction, which is beneficial to gallbladder and stone removal. In addition, some studies have shown that after taking qi-regulating drugs (Hangshao, Chenpi, Radix Aucklandiae and Fructus Aurantii), the sphincter movement cycle, diastolic period and bile duct pressure are prolonged, which is more significant than that of Danlidan recipe.
3. 1.2 Effect of traditional Chinese medicine on duodenal function
Bile excretion is not only affected by the internal pressure of biliary tract, the coordinated activity of gallbladder and sphincter, but also related to the functional state of duodenum.
3. 1.3 Anti-infection effect of traditional Chinese medicine
Clinically, cholelithiasis is often accompanied by acute biliary tract infection. Studies have proved that some cholagogic Chinese medicines have antibacterial and anti-inflammatory effects. Qingdan injection and its components such as Radix Gentianae, Herba Lysimachiae Christinae, Radix Bupleuri, Fructus Forsythiae, Fructus Aurantii Immaturus, Radix et Rhizoma Rhei, and Herba Taraxaci can alleviate chronic inflammation in rats and inhibit capillary permeability.
4 Research progress of modern medicine on gallstones
4. 1 classification of gallstones
Cholesterol calculus; Bile pigment calculus; Mixed calculus; There is also a black stone.
4.2 Symptoms of cholecystolithiasis
Patients with cholecystolithiasis can be asymptomatic in clinic, and many patients accidentally find it when doing B-ultrasound examination. Even most patients with gallstones can be asymptomatic for life, which is called static gallstones. The presence or absence of symptoms is related to the size, location, obstruction, inflammation and gallbladder function of the stone.
4.3 Research progress on the etiology of cholecystolithiasis
Gallbladder stone is a kind of stone with cholesterol as the main component. The establishment of cholesterol phospholipid vesicles and cholesterol nucleation theory has made the research on the causes of cholesterol stones develop to a new stage. As far as the pathogenesis of cholesterol gallstones is concerned, it involves three types: supersaturation of bile cholesterol, cholesterol nucleation and abnormal gallbladder function.
Composition of Chinese Medicine Paishi Decoction
According to years of clinical experience, the prescription for treating gallstones consists of Lysimachia christinae, Lygodium japonicum, talc, Semen Lepidii, Semen Sesami Niger, Radix Clematidis, Radix Bupleuri, Radix Paeoniae Alba, Fructus Toosendan, Atractylodis Macrocephalae and Poria. Lysimachia christinae, Endothelium Corneum Gigeriae Galli, Spora Lygodii and Bupleuri Radix have the effects of soothing the liver, regulating qi, clearing away heat and promoting diuresis, promoting gallbladder function and expelling stones. Radix Paeoniae Alba and Fructus Toosendan can soften liver and relieve pain; Clematis chinensis has the function of softening and resolving hard mass; Talc, Lepidium, Atractylodes macrocephala and Poria are all water-benefiting; Black sesame can tonify essence and blood. The whole prescription has the effects of soothing the liver, benefiting gallbladder, relieving spasm and pain, and dissolving and expelling stones. Modern clinic has proved that Lysimachia christinae is beneficial to gallbladder function, can dissolve stones and treat intrahepatic bile duct stones. The cholagogic effect may be to promote the secretion of bile by hepatocytes, increase bile in the liver and gallbladder, increase internal pressure, relax Oddi sphincter, and lead to increased bile excretion. Bupleurum chinense can increase bile excretion, reduce the concentration of bile acid, bile pigment and cholesterol, and relax Oddi sphincter and vinegar.
6 conclusion
Clinical verification shows that Chinese medicine Paishi decoction is tolerant and safe to use. It has obvious dissolution effect on gallstones in vitro. It has analgesic and anti-inflammatory effects, and has obvious inhibitory effect on acute and chronic inflammation. It has no effect on cholesterol content in normal serum. Has the function of increasing bile flow. It has obvious cholagogic effect.
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