But it has the longest history. As far as I know, it is Beijing Henian Hall, which was built in 1450 (the third year of Yongle in the Ming Dynasty) and is now very famous.
These time-honored brands are effective and don't deceive the masses!
Now the famous old pharmacies are:
Jiuzhitang in Changsha was founded in 1650.
Huqingyutang in Hangzhou was founded in 1874.
These time-honored brands can achieve good curative effect, and do not deceive the masses, otherwise they will not fail for hundreds of years!