Huangdi Neijing is divided into Su Wen and Ling Shu, each with 8 1 and 162.

Su Wen mainly discusses the changing law of nature, five movements and six qi, the relationship between man and nature, physiology, pathology, etiology, diagnosis, treatment principles, drugs, diseases and syndromes, treatment methods and health preservation.

Lingshu mainly discusses the changing laws of natural things, man and nature, human physiology, etiology and pathogenesis, intake, diagnosis, treatment and medical ethics. The core of Lingshu is the theory of zang-fu organs and meridians.

Theoretically, Huangdi Neijing established the following theories for traditional medicine, namely, the theory of yin and yang and five elements, the theory of pulse condition, the theory of zang-xiang, the theory of meridians, the theory of etiology, pathogenesis, disease syndrome, diagnosis method, treatment, health preservation and luck theory.

Another important content of Huangdi Neijing is the establishment of the theory of luck, which is used to study "five movements and six qi". It is based on the theory of five yin, six qi and three Yin San yang, and cooperates with heavenly stems and earthly branches to measure the laws of climate change and epidemic development of diseases. This is an academic theory of "correspondence between man and nature", which unifies the physiological changes of human body with the changes of natural climate.