As far as I know, Niuhuang Qingxin Pills produced by Beijing Tongrentang do not use natural Niuhuang varieties, but also include in vitro culture. The instructions all indicate "artificial bezoar". Except for emergency medicines such as Angong Niuhuang Pill, which must be cultivated naturally or in vitro, other medicines that need bezoar are made of artificial bezoar. After all, natural costs are high and quantity is scarce.

The main difference lies in whether gold is included or not and the dosage form. The main dosage forms are honeyed pills and honeyed pills.

Gold-plated clothes are a little more expensive, and gold-plated clothes are added to enhance the effect of calming the nerves.

As for the comparison between artificial and natural effects, it is of course natural in theory, but the difference in curative effect is not obvious at present.

The full name of Tongrentang Qingxin Pill is Tongren Niuhuang Qingxin Pill, which is different from the general Niuhuang Qingxin Pill in that the word Tongren is added. The difference is that one is taken from Taiping Huimin Hutchison Bureau, also known as the Bureau; Tong Ren Tang's prescription is self-prescribed. It seems that the prescription is 29 kinds of drugs, and Tongrentang is 27 kinds of drugs, except cinnabar and realgar in the original prescription. In contrast, it is safer for colleagues to clear their hearts after taking it for a long time, because cinnabar and realgar contain mercury, which is easy to be poisoned after taking it frequently.

I think the purpose of gold coating is to make up for the removal of cinnabar and realgar, and to enhance the calming and tranquilizing effect with gold foil.