It is also profound to translate this truth into the medical field, reminding us that doctors should "walk on thin ice" all the time, because diseases are complex and changeable, and each patient is different. The effectiveness of treatment at that time did not mean that it was the end point of disease treatment.
Outpatient treatment, especially some functional gastrointestinal diseases, such as functional dyspepsia, chronic gastritis, gastroesophageal reflux, irritable bowel syndrome, etc. , often effective. Whenever this time, I will remind myself not to be complacent. As the saying goes, don't be too happy. Because of the characteristics of these diseases, they have a high recurrence rate. After a period of Chinese medicine treatment, the symptoms of discomfort will be relieved quickly, but after some adverse factors, the disease will recur.
There are more and more heartburn and acid reflux patients in outpatient department. We generally judge that these people are suffering from a common digestive system disease: gastroesophageal reflux disease.
Western medicine has three weapons to treat gastroesophageal reflux disease. The first is the well-known "Laszlo" drugs, such as omeprazole, rabeprazole, esomeprazole and so on. , can inhibit gastric acid. It is considered by western medicine as a first-line drug to treat gastroesophageal reflux disease, especially reflux esophagitis with damaged esophageal mucosa under endoscope. It can be said that Laszlo can be used for all refluxes. In addition, there are therapeutic drugs such as accelerant such as mosapride and mucosal protective agent such as teprenone.
As digestive doctors in traditional Chinese medicine hospital, many patients we meet seek Chinese medicine solutions after the failure of routine treatment in western medicine. Many patients with acid regurgitation and heartburn have no effect after taking "lazole", but they can't stop taking it, and repeat it as soon as they stop taking it.
"Lazole" drugs are widely used to inhibit gastric acid in clinic, but they have adverse reactions after long-term use. The FDA solemnly warned that long-term use may lead to indigestion, gastric fundus gland polyps, atrophic gastritis, intestinal flora imbalance, cardiovascular events, osteoporosis, and even drug dependence and other adverse reactions.
Traditional Chinese medicine pays attention to syndrome differentiation and treatment, and determines therapeutic drugs according to patients' syndrome types. In clinical research, we found that the TCM syndromes of patients with acid reflux and heartburn are mostly liver-stomach stagnation and heat syndrome, spleen deficiency and damp-heat syndrome and cold-heat mixed syndrome, accounting for about 80.90% of the total number of patients. The theory of regulating the spleen and stomach put forward by the late Academician Tung Chee-hwa emphasizes the recovery of the physiological characteristics of the stomach, which has been widely recognized by the industry. The Spleen and Stomach Department of Xiyuan Hospital has developed three kinds of drugs for treating gastroesophageal reflux according to the theory of dredging and descending and clinical practice:
The preliminary research results of the above three drugs show that the dialectical use of the above three different drugs has the characteristics of overall regulation and individualized treatment for heartburn and acid reflux in patients with gastroesophageal reflux, and has unique advantages and broad prospects. It just solves the problem that "the antacid can't stop".
In order to solve the problem of these patients with acid reflux and heartburn who can't stop taking medicine, the Spleen and Stomach Department of Xiyuan Hospital carried out a multicenter, randomized, double-blind, placebo-controlled clinical study on the treatment of non-erosive reflux disease by combining Tongjiang theory with syndrome differentiation and stopping taking medicine with acid-lowering inhibitors, which was approved and funded by the Ministry of Science and Technology (project number: 20 19YFC 1709604).
This study is aimed at patients with gastric acid reflux and heartburn who can't stop using acid inhibitors. According to different syndromes, the doctor will prescribe the above three different traditional Chinese medicines, and with the assistance of traditional Chinese medicines, gradually reduce the dosage of "lazole" until the drug is finally stopped. Patients who are willing to participate in this study can judge for themselves first. If they really meet the above conditions, they can go to the Spleen and Stomach Department of Xiyuan Hospital for consultation. This study has been audited by the Ethics Committee of Xiyuan Hospital of Chinese Academy of Traditional Chinese Medicine, and your rights and interests will be fully protected.
Subjects were selected under the following conditions:
1, which meets the diagnostic criteria of non-erosive reflux disease;
2. Acid inhibitors (PPIs) are effective after continuous treatment for more than 8 weeks, and relapse immediately after withdrawal;
3. The age is between 18-70 years old;
4. Meet the diagnostic criteria of stagnation of heat in liver and stomach, dampness-heat syndrome due to spleen deficiency and mixed cold and heat syndrome in traditional Chinese medicine;
5. Patients have informed consent and are willing to receive corresponding treatment.
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