There will be an index called "alanine aminotransferase" in the blood items of general physical examination, which is a catalyst and exists in human liver in large quantities. Under normal circumstances, the content of transaminase in blood is very small.
However, if you suffer from liver diseases (such as hepatitis, alcoholic hepatitis, fatty liver, cirrhosis, etc.). ), liver cells will be destroyed, and transaminase in the blood will increase, leading to excessive detection; In addition, acute heart diseases such as myocarditis and myocardial infarction may also increase the content of transaminase in the blood; There are also some drugs that may damage liver function and cause abnormal increase of transaminase, such as antipyretic and analgesic drugs, some antibiotics and traditional Chinese medicine.
Therefore, the day before the examination, pay attention to avoid staying up late, overworking and strenuous exercise. It is best not to eat big fish and drink big meat, try not to eat midnight snack, and leave enough fasting time for the next day's examination.
In addition, the high alanine aminotransferase found in the examination does not necessarily mean that there is something wrong with the liver. You can compare the physiological conditions mentioned above and do another review within three months.
Elevated transaminase is a very common situation, but it is not necessarily a problem with the liver and hepatitis occurs. Healthy normal people will also have elevated transaminase, because transaminase is very sensitive, and many factors will lead to fluctuations in the normal value of transaminase. Healthy people may be examined at different times of the day, and the results of transaminase measurement may be different. After strenuous exercise, overwork, eating greasy food or drinking alcohol before examination. Will cause an increase in transaminase.
If the test results show that transaminase is elevated, under normal circumstances, the doctor will recommend re-examination, and at the same time, the liver function and B-ultrasound of liver, gallbladder and spleen will be checked, and a comprehensive judgment will be made according to these results. There are two kinds of serum transaminase, one is alanine transaminase ALT and the other is aspartate transaminase AST. Generally speaking, the normal range of two kinds of transaminase is 0-40 iu/L, and aspartate transaminase AST reflects the damage of hepatocyte mitochondria, which can better explain the damage degree of liver tissue.