Yes, persistence is the most important. Last year my weight was 170kg, and this year my weight will be 126 (but, to my shame, I exercise intermittently). The most important thing to lose weight is to persist, don't give up, don't be discouraged, and believe that you will succeed! It is suggested that running, skipping rope or pressing buttons are all good ways to lose weight. However, you must eat rice and pay attention to the collocation of nutrition. Otherwise the body will be overwhelmed. Remember, don't lose weight in a hurry. Since you ask if it is possible to lose 50 pounds a year, I think you are determined to lose weight! Come on! Yes!