Pharmacokinetics: The data show that the bioavailability of this product in healthy volunteers is 80%, and it can be absorbed rapidly after oral administration, and the plasma concentration reaches the peak after 1.5 ~ 2.0 hours, and it is 30, 60,115 after 3.75, 7.5 and 15mg administration respectively. Drug absorption is not affected by gender, administration time and repeated administration. The drug is rapidly distributed from blood vessels to the whole body, the distribution volume is100 L L, the plasma protein binding rate is 45%, and the elimination half-life is about 5 hours. Repeated administration has no cumulative effect. This product is extensively metabolized in the body (mainly biotransformed by P450 enzyme system), and the main metabolites are N- oxide (pharmacologically active to animals) and N- demethylation (inactive). Metabolites are mainly excreted through the lungs (about 50% of the dose), and the rest are excreted through urine. Only 4 ~ 5% of the dose is excreted from the body with urine as raw material. The half-life of the elderly is about 7 hours. Due to slow demethylation, the plasma elimination ability of patients with liver cirrhosis is obviously reduced, so the dose should be adjusted. This product can pass through dialysis membrane. Zopiclone tablets are also sedatives and sleeping pills.