Efficacy, function and taboo of Trichosanthes kirilowii shell, also known as Trichosanthes kirilowii shell, is a common Chinese herbal medicine. It comes from the skin of Trichosanthes kirilowii, a cucurbitaceae plant, which can moisten the lungs and resolve phlegm, and its medicinal effect is particularly excellent. Let's take a look at the efficacy, function and taboo of Trichosanthes kirilowii shell.

Efficacy, Function and Taboos of Fructus Trichosanthis Shell 1 Efficacy, Function and Taboos of Fructus Trichosanthis Shell

1, the efficacy of Trichosanthes kirilowii shell

The shell of Trichosanthes kirilowii is sweet and cold. It can enter the lung meridian and stomach meridian, and has many effects such as moistening lung and resolving phlegm, benefiting qi and broadening chest. Can be used for treating cough, sore throat, chest pain, hematemesis, etc. Its therapeutic effect is very obvious. During normal smelting treatment, it can be decocted with clear water.

2, Chinese medicine Trichosanthes kirilowii shell can cure toothache.

Trichosanthes kirilowii shell can reduce swelling and relieve pain, and has a good therapeutic effect on human toothache. In normal treatment, Trichosanthes kirilowii shell and nidus vespae can be burned together, and then Vitex negundo root and onion root can be decocted, which can quickly relieve the symptoms of toothache.

3, Chinese medicine Trichosanthes kirilowii shell can treat breast abscess swelling and pain.

Trichosanthes kirilowii shell also has a good therapeutic effect on human breast abscess and swelling and pain caused by breast abscess. In normal treatment, you can add four dollars of Trichosanthes kirilowii shell to five dollars of dandelion and decoct it with water once a day, and the symptoms will get better soon.

4. Taboo of Trichosanthes kirilowii shell.

Although the medicinal effect of Trichosanthes kirilowii shell is excellent, there are some taboos when taking it. The most important thing is spleen deficiency and damp phlegm, and people with weak spleen and stomach can't take Trichosanthes kirilowii shells.

Efficacy, Function and Taboos of Trichosanthes kirilowii Shell 2 (1) Different parts of Trichosanthes kirilowii have different efficacy.

Whole fructus trichosanthis

Clearing away heat and dissipating stagnation, moistening lung and resolving phlegm, moistening intestine and relaxing bowels. Piren together is the whole Fructus Trichosanthis, but now pharmacies generally only have Fructus Trichosanthis and Fructus Trichosanthis. If the prescription uses whole Trichosanthes kirilowii, pharmacies generally ration 1/3 Trichosanthes kirilowii skin and 2/3 Trichosanthes kirilowii kernel. Trichosanthes kirilowii not only has the function of both skin and kernel, but also has the function of reducing swelling and resolving hard mass, which can be used to treat swelling and pain of breast carbuncle.

Trichosanthes peel

That is, Trichosanthes kirilowii has the effects of clearing away lung-heat, resolving phlegm, promoting circulation of qi and widening chest, and can be used to treat abdominal distension, fullness of chest and diaphragm, cough due to lung heat, and cough with thick phlegm. In recent years, it is also often used to treat coronary heart disease and angina pectoris.

root of Chinese trichosanthes

Reduce blood fat, prevent arteriosclerosis, promote cell growth, prevent anemia and resist radiation. Regular consumption can improve human immunity (Practical Science and Technology, No.2003 10). In clinical application, Trichosanthes root has a good effect in inducing labor for second trimester pregnancy, stillbirth and overdue abortion, which is safe and reliable.

Trichosanthes seed

That is, Trichosanthes kirilowii seeds have the functions of moistening cotton, promoting lactation, nourishing and beautifying, invigorating stomach and moistening lung, relaxing bowels, inducing diuresis, broadening chest, calming nerves, resisting bacteria and strengthening body, and have a strong inhibitory effect on the proliferation of choriocarcinoma cells in vitro and HIV.

Modern medical research has proved that Fructus Trichosanthis contains 16.8% unsaturated fatty acids and 5.46% protein, and contains 17 kinds of amino acids, saponins, vitamins and 16 kinds of trace elements such as calcium, iron, zinc and selenium. Eating Trichosanthes kirilowii seeds can dilate the coronary artery of the heart and increase the coronary flow; It has obvious protective effect on acute myocardial ischemia; It has a strong inhibitory effect on the proliferation of choriocarcinoma cells in vitro and HIV; It has a certain therapeutic effect on diabetes; It has auxiliary effect on hypertension, hyperlipidemia and hypercholesterolemia; Can improve the immune function of the body; And has the effects of slimming and beautifying.

(2) The efficacy of Fructus Trichosanthis

clear heat and eliminate phlegm

Used for phlegm-heat cough and asthma. This taste is sweet, cold and moist, and it has the effect of clearing away lung heat and resolving phlegm. It is used for cough due to lung heat, and thick phlegm is not easy to cough up. It can be used alone, and is often combined with Anemarrhena asphodeloides and Fritillaria thunbergii in clinic. Scutellaria baicalensis Georgi, Arisaema cum bile, Fructus Aurantii Immaturus, etc. Those with phlegm heat, yellow and thick expectoration, chest tightness and poor stool can be added, such as Qingqi Huatan Pill.

Clinically, it is very effective to treat cough with boiling water, especially for paroxysmal cough with phlegm.

Promoting qi circulation and broadening chest

Can be used for treating thoracic obstruction and thoracic obstruction. This product can not only clear phlegm and clear heat, but also relieve chest pain, so it can clear chest pain and is an important drug for treating chest pain. It can be used with Bulbus Allii Macrostemon and Rhizoma Pinelliae for treating chest obstruction caused by phlegm, such as Bulbus Allii Macrostemon White Liquor Decoction and Bulbus Allii Macrostemon Pinelliae Decoction. Rhizoma Coptidis and Rhizoma Pinelliae, such as Xiaoxinxiong Decoction, are used to treat phlegm-heat chest distress and chest pain.

Eliminate carbuncle and loose knot

Used for lung carbuncle, intestinal carbuncle, breast carbuncle, etc. This product can relieve swelling and dissipate stagnation. This product is used together with Houttuynia cordata and Phragmites communis to treat lung abscess, cough and purulent blood. For intestinal carbuncle, it is often used with Patrinia herb and Sargentodoxa. It can be used together with Taraxacum mongolicum, Flos Lonicerae and Fructus Arctii to treat swelling, swelling, heat and pain at the beginning of breast carbuncle.

purge

Used for constipation due to intestinal dryness. Trichosanthes kirilowii kernel is moist and oily, which has the effect of moistening intestines and relaxing bowels. It is often combined with Fructus Cannabis and Semen Pruni to treat excess heat in gastrointestinal tract, dry intestine and constipation.

Function of Trichosanthes kirilowii

Effects on cardiovascular system

Trichosanthes kirilowii decoction has certain inhibitory effect on drug-induced arrhythmia. The results showed that Fructus Trichosanthis decoction could prevent ventricular fibrillation induced by calcium chloride in rats by intraperitoneal injection in advance. It can also significantly increase the threshold dose of ouabain-induced ventricular tachycardia in guinea pigs; It can prolong the latency of aconitine-induced arrhythmia in rats, but there is no significant difference in statistics. Intraperitoneal injection of Fructus Trichosanthis decoction in normal anesthetized rats can obviously prolong the P-R, Q-T and R-R intervals of ECG. .

Effect on digestive system

Trichosanthes kirilowii contains purgative substances and has purgative effect. The purgative effect of Trichosanthes kirilowii bark is weak; The fatty oil contained in melon basket kernel has a strong diarrhea-inducing effect; The purgative effect of Gualou ointment is relatively mild. The ethanol extract of Trichosanthes kirilowii can inhibit the gastric mucosal injury caused by pyloric ligation, 5- hydroxytryptamine and ethanol hydrochloride, and the ethanol extract of Trichosanthes kirilowii can obviously inhibit the ileal contraction caused by acetylcholine in mice.

Antibiotic action

In vitro experiments show that the decoction or infusion of Trichosanthes kirilowii has inhibitory effect on gram-negative intestinal pathogens such as Escherichia coli, Staphylococcus, Pneumococcus, Hemolytic Streptococcus A and Influenza Bacillus. In addition, it also has inhibitory effect on skin pathogenic fungi such as Cyclobalanopsis and Nocardia stellata.

Antitumor effect

In vitro experiments showed that the decoction of Trichosanthes kirilowii and the extracts of Trichosanthes kirilowii bark and Trichosanthes kirilowii kernel had killing effects on ascites cancer cells in mice. The anti-cancer effect of Trichosanthes kirilowii bark in vitro is better than that of Trichosanthes kirilowii kernel, and the 60% ethanol extract has the strongest effect. The white amorphous powder obtained from the ether extract of Trichosanthes kirilowii bark also has anti-cancer effect in vitro, but the seed shell and fatty oil are ineffective. Animal experiments show that Trichosanthes kirilowii has a certain inhibitory effect on sarcoma, but it has no obvious effect on ascites cancer.

Other functions

In vitro experiments showed that Trichosanthes kirilowii injection could significantly inhibit platelet aggregation and TXA2 synthesis induced by ADP and arachidonic acid, and its action intensity was dose-dependent. Intraperitoneal injection of Trichosanthes kirilowii can also significantly reduce the maximum platelet aggregation rate and platelet aggregation rate after coronary artery ligation 1 hour and reperfusion for 23 hours. Trichosanthes kirilowii acid, an effective component of Trichosanthes kirilowii, has a concentration-dependent inhibitory effect on platelet aggregation induced by collagen, adenosine diphosphate and adrenaline. The inhibitory effect of Trichosanthes kirilowii on platelet aggregation may be related to the inhibition of platelet cyclooxygenase activity and the reduction of TXA2 formation.

The water extract of Trichosanthes kirilowii can increase blood sugar in rabbits by gavage, but it has no obvious effect on liver glycogen and muscle glycogen. The amino acids contained in Trichosanthes kirilowii bark have expectorant effect.