Avascular necrosis of femoral head is a common disease in orthopedics and a worldwide problem. The disease is often caused by long-term clinical use of hormones, trauma, drinking, etc. At the same time, the patient has persistent pain in the hip joint, complicated with walking difficulties and even paralysis. No effective chemical drugs have been found in the world. According to the theory of traditional Chinese medicine, avascular necrosis of femoral head is mainly caused by blood stasis in tendons and veins in the early, middle and late stages, and is often accompanied by liver and kidney deficiency in the late stage. Hormone or alcoholism is often accompanied by phlegm and dampness. Once avascular necrosis of femoral head occurs, even if hormone is stopped immediately, it is difficult to stop the development of the disease. Most patients will experience the "painful trilogy" of ischemic necrosis-collapse-osteoarthritis, and the course of disease ranges from months to years. Hip joint pain persists, while walking is difficult and even paralyzed.
Although great progress has been made in the diagnosis and treatment of the disease at present, there is still no big breakthrough in treatment, especially drug treatment is still a worldwide problem. At present, there are many methods to treat avascular necrosis of femoral head, but there is no definite recognized effect. There is no ideal chemotherapy in the world. At present, artificial femoral head replacement is usually used.
Artificial femoral head replacement seriously affects the quality of life of patients.
According to the statistics of experts from the University of Virginia, about 50% patients with avascular necrosis of the femoral head in the world have undergone artificial femoral head replacement before the age of 40. The failure rate is about 10% ~ 50% within 5 years after operation. And the best artificial femoral head can only be used for 10 ~ 15 years. According to the current average life expectancy, these patients will have to be replaced at least three times in the remaining 30 to 40 years. Seriously affect the quality of life of patients.
A "stubborn disease" that traditional therapy can't overcome.
The main problems in clinical treatment of this disease are as follows:
First, there are no effective preventive measures and drugs for high-risk groups;
Second, there are no therapeutic drugs in subclinical stage;
Third, after the course of the disease enters the advanced stage, the patient will eventually encounter surgery;
Fourth, even if surgical treatment is adopted, it is difficult to improve the surgical effect without adjuvant drugs;
Fifth, the effect of replacing the artificial femoral head should be guaranteed, but it is expensive and has great limitations.
Six, Chinese medicine treatment mainly adopts Chinese medicine fumigation, plaster, acupuncture, oral administration of Chinese medicine and other methods, with promoting blood circulation and removing blood stasis, tonifying kidney and strengthening bones as the main means. It has a certain effect on relieving pain. But it is not organically combined with pathology, objective curative effect standard and long-term clinical evidence.