The main component of wine is alcohol, which is a high calorie. Liver sugar that cannot be converted into human metabolism. The body will directly convert the sugar in alcohol into fat for storage. Naturally, I can't lose weight. People who like drinking will affect the synthesis of protein. When protein synthesis decreases, muscle mass will decrease. The calorie of alcohol is 1 g, releasing 7 kilocalories, which is higher than protein and carbohydrates (4 kilocalories) and only lower than fat (9 kilocalories), so drinking alcohol will definitely make you fat.

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1. The liver is the main place where endogenous glucose is produced, which is what we call gluconeogenesis energy supply mode. When alcohol causes liver tissue damage, the storage, decomposition and gluconeogenesis of liver glycogen will be weakened.

2. The liver is the main place of insulin metabolism. The damage of alcohol to liver tissue will slow down the speed of insulin metabolizing enzymes, prolong the half-life and promote hypoglycemia.

3. In addition, ethanol can stimulate the increase of insulin secretion, leading to hypoglycemia.