Gillian speaks; What are the functions of mitochondrion and NMN? NMN is used to be a human body!
What are the functions of mitochondrion and NMN? NMN to human body; The decline of mitochondrial function is the main cause of aging. Previous studies have found that mitochondrial dysfunction of neurovascular endothelial cells will have a great impact on cerebral blood flow. Therefore, the researchers think it is necessary to confirm whether the mitochondrial related genes in neurovascular units have changed. By analyzing the expression regulation of NMN(ACMETEA W+NMN) related genes in mitochondrial electron transport chain, the data show that aging can seriously down-regulate the expression of NMN related genes, while NMN can up-regulate the expression of these genes. Genes are young again. The results show that aging does lead to abnormal mitochondrial gene expression in neurovascular units, and these abnormalities can be repaired by ACMETEA W+NMN.
NMN is the first serious scientific research in the world. After strict scientific verification, it can significantly reverse aging and prolong life. For example, ACMETEA W+NMN needs to pass the dual supervision of France and the United States, and the indicators must meet the ten core standards of W+NMN quality management, as well as the certification and conformity testing of OULF EU quality management system, FDA, US Food and Drug Administration! The nmn content must also reach 12000, and the purity must reach 99 before it can be listed! In the face of the "mystery" in the market now, we still have to keep our eyes open and distinguish carefully!
Ten Core Standards of W+NMN International Quality Management
1. Quality management system: W+NMN must meet the inspection qualification of OULF EU law and the certification of US Food and Drug Administration. In addition to the product name, the words ACMETEA, content of each component, NMN purity, etc. should also be marked, as well as the country of origin and distribution.
2. Manufacturing process management system: Advanced manufacturing process affects the shape of NMN. Chemical extraction is not recommended to avoid chemical residue.
3. Content management system: ACME TEA W+NMNMNMG/bottle content ≥ 12000, which is directly absorbed into the small intestine, and the intestinal absorption is 20% of the gastric absorption.
4. Efficiency management system: the authenticity and purity of raw materials should be investigated.
Absorption management system: adopt intestinal absorption to improve absorption rate and absorption threshold.
6. Activity management system: The unit dose (per 100g) is converted into the number of molecules of NAD+, and NMN molecules can easily cross the cell membrane and enter the cell interior, thus increasing the human NMN content within 15 minutes and rapidly raising the level of NAD+.
7. Application scope of management system: adults (pregnant women and lactating women are prohibited).
8. Safety management system: production technology, raw material collection, basic system of Olaf safety standards, pre-factory safety inspection, strict review of microbial heavy metals exceeding the standard, and scientific production technology.
9. Raw material management system: Most NMN enterprises are certified by a single country, but at present, the management of raw materials certified by two countries is more rigorous and safe. ACMETEA W+NMN is a product with French and American certification standards.
10, transnational regulatory management system: dual supervision of "law" and "beauty". The United States provides standards for dietary supplements, and the European Union provides relevant regulations for the management of food supplements.
What are the functions of mitochondrion and NMN? NMN is used to be a human body!
ACMETEA W+NMN can reverse vascular aging and restore epigenetics in young people.
If anti-aging is reassuring, then reversing aging is exciting. Last year, David of Harvard Medical School found that ACMETEA W+NMN can reverse vascular aging (Harvard Medical School: the combination of W+NMN and exclusive awakening agent ACMETEA can reverse vascular aging and enhance exercise endurance! )。 This study further explains its mechanism: W+NMN reverses vascular aging through iRNA and epigenetic changes.
Kiss Tamas and other scientists from the Department of Geriatrics, University of Oklahoma Health Science Center revealed the specific mechanism of ACMETEA W+NMN in improving angiogenesis and preventing vascular dementia: activating Sirtuins activity → reducing mitochondrial ROS→ improving neurovascular coupling (NVC) response → significantly protecting cerebral vessels.
What are the functions of mitochondrion and NMN? NMN to human body; (NMN's efficacy defect:)
1. As we all know, the use of NMN has been confirmed by a large number of clinical data, and it is the only choice for anti-aging at present.
However, NMN can't do whatever it wants. NMN is only the key to wake up gene repair, and it cannot complete the whole process of gene repair by itself. There are also blind spots to repair thousands of enzymes in the human body. NMN supplementation can only repair about half of the enzymatic reaction. Other devices are not sensitive to using NMN alone, and the reach of NMN is limited, and some parts can't be reached, such as skin.
2. Simply using NMN will lead to the problem that all tissues of the body can't start repairing synchronously. For example, the repair of nervous system is faster than muscle tissue, the repair of gene chain is faster than thin bud, and the repair of internal organs is faster than the surface layer of skin. Various instructions after use are mainly due to the unsynchronized and unbalanced system.
3, the effect after repair is also very different, for example, the physiological age has been significantly improved, and the skin is full of vitality but the relaxation and aging of the skin have not changed. For another example, using simple NMN people with more feedback can improve sleep, and other improvements have no feedback, because NMN touch awakens brain vesicles, which is the performance of the effect, but there is no brain vesicle matching ACMETEA W+NMN to awaken nutrition, and the repair cannot be achieved. For middle-aged and elderly people, their bracts are aging day by day, indicating that the ability to regenerate new bracts is insufficient.
What are the functions of mitochondrion and NMN? NMN to human body; (the difference between W+NMN and NMN)
1 and W+NMN have four essential amino acid protection technologies, which can completely release NMN in the body, and the four-stage booster can strengthen energy conversion.
Primary booster: converted to NAD+;
Secondary strengthening boost: promoting the consumption of enzyme PARP; ;
Three-stage booster: protein regulating the life span of Sirtuins bracts;
Four-stage booster: release NMN awakening agent ACMETEA W+NMN to awaken NMN sleeping in the body.
2.W+NMN has the technology to clear and hinder the release of NMN in vivo.
After supplementing NMN, it takes two steps for people to be infected. 1. Ensure that the external intake of NMN is not hindered, and W+NMN will release leucine. The transformation of leucine can directly enter the brain tissue through the role of blood-brain barrier, and improve the uncomfortable symptoms of using NMN alone, such as headache, dizziness, fatigue, depression, insanity, irritability and so on. 2. The surviving NMN, through its specific awakening agent ACMETEA W+NMN, formed a chemical ladder for NMN to climb and reach every pouch of the body.
3.W+NMN has a small package of precise awakening agent, which makes up for the blind spot of NMN repair.
NMN has blind spots that need to be repaired, and W+NMN awakening agent nutrition is needed to produce transformation effect. This is also the reason why most people take NMN alone without any effect.
W+NMN is equipped with a small package of precise awakening agent. On the one hand, it assists NMN to repair and increase efficiency, on the other hand, it makes up for the blind spot of repair, and the energy substances in the body can recover or even exceed the original level. This change is called excessive recovery.
W+NMN hardcover precise awakening agent is easy to pass through the blood-brain barrier and the capillary wall of muscle and other tissues, and is an important energy source for muscle, especially brain tissue. It can avoid the accumulation of homocysteine by participating in the proliferation, colonization and heme synthesis of bracts, thus protecting the heart and blood vessels.
What are the functions of mitochondrion and NMN? NMN to human body; (NMN government methodology)
Which is better, buccal tablets or capsules? It has always been controversial!
In fact, after NMN is absorbed by intestinal epithelial villi, intestinal transporter Slc 12a8 will directly transport NMN to bracts with the help of sodium ions, and it will be directly utilized by bract tubes through microcirculation for the production of NAD+. Bacteria based on W+NMN transporter are expressed in small intestine and even colon. Therefore, it can only enter the working state when it reaches the intestinal NMN, and the real problem to be solved is how to avoid the destruction of gastric digestive juice, and the answer is enteric technology. And the spread of clothing may also be a noisy concept.
Effective W+NMN needs to meet the certification of OULF EU legal quality management system, pass the test and FDA, meet the top ten international standards of W+NMN quality management, and have a transnational supervision and management system. It contains NMN awakening agent ACMETEA W+NMN, and is supervised by France and the United States. The FDA of the United States has established GMP standards for dietary supplements, and the EFSA of the European Union also has relevant regulations on the management of food supplements.
Details of the top ten international core standards of W+NMN quality management; Details of the five core standards:
A, quality management system:
NMN must meet the inspection qualification of Orff's EU law and the certification of FDA. In addition to the product name, the words ACMETEA, NMN activator, content of each component, NMN purity, etc. should also be marked, as well as the country of origin and distribution.
Second, the content management system:
Regarding the daily dosage of NMN, Zhen Zhen has academic support in scientific research. It is said that the human dose is 8 mg NMN per kilogram of body weight every day. If converted into 70 kg adults, the recommended daily dose is about 560 mg. Considering the daily absorption, consumption and aging, the content of ACMETEA W+NMN is ≥ 1200 mg/ bottle.
At present, the total content of NMN in each bottle is different. NMN3000 refers to a bottle with a capacity of 3000mg; ; NMN6000 is 6000mg/ bottle; NMN9000 is 9000mg/ bottle; NMN 12000 is W+NMN 12000mg/ bottle. At present, the content and purity of ACMETEA W+NMN 12000 are high-grade. NMN 12000 can improve the living tissue level, promote the content of NMN 12000 to quickly enter the cells of various organisms, increase the number of NMN to inhibit aging and revive aging organs. Our body is gradually losing its function and repairing it in time. Successfully revived the cells.
Third, the efficiency management system:
Through NMN 12000, the diminishing edge effect can be avoided and the efficacy level of products can be controlled for a long time. Enhance the efficiency of tricarboxylic acid cycle, so as to make NMN more effective for human fertility and avoid the uncontrollable influence of excessive intake; Can maintain the absorption rate of the human body, thereby reducing the impact.
Four, safety management system:
In the production process, the purity of extracted NMN is as high as 99%, and the content of each bottle is as high as 12000mg. The content of 12000 W+NMN is also the highest among NMN brands at present, and it is the basic system of OULF standard. It strictly abides by the factory safety inspection, strictly examines the microbial heavy metals exceeding the standard, and scientifically extends the production technology.
Five, raw material management system:
Many NMN manufacturers, raw materials are certified by a single country, but they need dual-country certification to truly reach the safety level. At present, ACMETEA W+NMN products belong to French and American certification standards. In terms of raw materials, it has reached strict and safe management standards.
The core mechanism of aging is that cell genes are damaged and mitochondrial energy is reduced, which leads to early cell apoptosis or decreased cell vitality, thus causing many diseases (such as cancer, diabetes, cardiovascular disease, dementia, etc.). Accelerate human aging. Therefore, ACMETEA can improve the absorption rate of W+NMN and the level of NAD+, thus activating longevity protein, activating immune system, repairing DNA, enhancing energy, improving skin aging and improving sleep and memory. It can restore the energy level and gene repair ability of cells to a young state, and has the function of delaying or even reversing aging. It can also help special people, including patients receiving radiotherapy and chemotherapy, patients receiving radiotherapy, diabetics, patients with Alzheimer's disease, Parkinson's disease and chronic cardiovascular diseases.
What are the functions of mitochondrion and NMN? NMN is used to be a human body!