List of articles: 1. Is the function of cephalosporin capsule anti-inflammatory? 2. What is the function of cephalosporin capsules? 3. What is the function of cefixime capsules? 4. Description and efficacy of cefixime capsules Is the function of cefixime capsules anti-inflammatory? The function of cephalosporin capsule is anti-inflammatory.
Cefoxime capsules belong to broad-spectrum antibiotics and are the third generation cephalosporins. They have good antibacterial activity against some Gram-positive bacteria and negative bacteria, and can be used to treat Gram-positive bacteria, negative bacteria, streptococcus, Escherichia coli and so on.
Treat respiratory tract infection, bronchitis, pneumonia and bronchiectasis.
It can also treat urinary system infections, such as pyelonephritis, cystitis and urethritis.
It has a certain therapeutic effect on cholecystitis and otitis media.
Cefexoxime capsules have adverse reactions such as diarrhea, abdominal pain and nausea.
Those who have a history of allergic reaction to cephalosporins are prohibited for children under 6 years old, and pregnant women and lactating women should use it with caution.
Patients need to take medicine under the guidance of a doctor or pharmacist, and don't drink alcohol during taking medicine to avoid side effects.
There are more than 30 kinds of cephalosporins. According to these kinds of drugs, cephalosporins can be divided into four categories. These drugs can be used to treat pneumonia, bronchitis, urinary tract and cholecystitis caused by sensitive bacteria. Care must be taken when using cefixime capsules. Children under 6 months should not use it. In the process of using drugs, it may also cause adverse reactions, such as rash or itching, fever, etc., which must be taken seriously.
During taking cefixime capsules, we must pay attention to alcohol prohibition, because taking drugs and drinking alcohol may affect the metabolic process of drugs in the body, which may even lead to syncope and even affect life.
What is the function of cephalosporin capsules? Cefaclor capsule is an antibiotic. Indications: This product is mainly suitable for respiratory system, urinary system, otolaryngology, skin and soft tissue infections caused by sensitive bacteria.
What function does cefixime capsule have? Kangzhijia affordable drug Ai Xin Health delivered to the door Cefexoxime Capsule ￥ 19.00 Cefexoxime Capsule is a newly developed cephalosporin antibiotic, and the third side chain of 7- aminocephalosporanic acid has vinyl group; Methoxyimino group with carboxyl group at position 7 is a hard capsule, and the contents are white or light yellow powder after removing the capsule.
Cefoxime capsules are suitable for tonsillitis, pharyngitis, acute bronchitis, acute attack of chronic bronchitis, otitis media, urinary tract infection and simple gonorrhea (cervicitis and urethritis) caused by sensitive bacteria. Cefoxime capsules are the third generation oral cephalosporins, which can play a bactericidal role by inhibiting the synthesis of bacterial cell walls.
Cefexoxime capsule has good antibacterial effect on Gram-positive cocci such as pneumococcus, Streptococcus pyogenes, Gram-negative bacilli such as influenza, Moraxella catarrhalis, Escherichia coli, Proteus mirabilis and Neisseria gonorrhoeae in vitro and in vivo.
The antibacterial effect on grape bacteria is poor; It has no antibacterial effect on Pseudomonas aeruginosa, Enterobacter, Bacteroides fragilis and Clostridium.
If you take other drugs at the same time, please consult a pharmacist or doctor first.
Description and efficacy of cefixime capsule (Oujian) are used for pharyngitis, tonsillitis, acute bronchitis and acute attack of chronic bronchitis, otitis media, urinary tract infection and simple gonorrhea (cervicitis or urethritis) caused by sensitive bacteria.
The following is the instruction manual of cefixime capsules I compiled. Welcome to reading.
Commodity introduction of cefixime capsules
Generic name: cefixime capsules
Manufacturer: Ou Yi Younuokang Pharmaceutical Co., Ltd.
Approval number: National Medicine Zhunzi H2004 1669
Drug specification: 0. 1g 12 capsules.
Drug price: ￥ 18.8 yuan.
Instructions for cefixime capsules
Common name cefixime capsule
Product Name Cefoxime Capsule (Oujian)
English name CefiximeCapsules
Pinyin Quanwharf Zuokezuo Capsule (occasionally)
Main ingredients cefixime capsules (Oujian) Main ingredients: cefixime.
Its chemical name is 7{[2- amino -4- thiazolyl [hydroxymethyl | imine |-acetyl] amino -3- vinyl -8- oxygen -5- thio-1- azabicyclo | 4,2,o]} -2- octyl-2-carboxylic acid.
Molecular formula: c65438+c16h15n5o7s2 3h2o.
Molecular weight: 507.50
Properties Cefoxime Capsule (Oujian) is a hard capsule, and its contents are white or yellowish powder.
Indications/Functions: Cefexoxime Capsule (Oujian) is suitable for pharyngitis, tonsillitis, acute bronchitis and acute attack of chronic bronchitis, otitis media, urinary tract infection and simple gonorrhea (cervicitis or urethritis) caused by sensitive bacteria.
Specification model 0. 1g 12s
Administration and dosage by oral administration.
Dosage for adults and children weighing over 30kg: oral, 0. 1g (1g) once, twice a day; Adult patients with severe infection can be increased to 0.2g(2 capsules) once and twice a day.
Children: take orally, the dosage is calculated as 65438+ 0.5 ~ 3.0 mg per kilogram each time, twice a day.
Still follow the doctor's advice.
Adverse reactions Most of the adverse reactions of cefixime are short-lived and mild.
Gastrointestinal reactions are common, including diarrhea 16%, increased stool frequency by 6%, abdominal pain by 3%, nausea by 7%, dyspepsia by 3% and abdominal distension by 4%. Adverse reactions with incidence less than 2% include rash, urticaria, drug fever, itching, headache and dizziness.
Laboratory abnormalities include transient increase of ALT, AST, ALP, LDH, bilirubin, BUN and Cr, transient decrease of platelet and white blood cell count, increase of eosinophils and positive direct antiglobulin test.
Contraindications: those who have a history of cefixime capsules (Oujian) or cephalosporin allergy are prohibited.
Note: 1. Those with a history of cephalosporin allergy are prohibited.
Use with caution in patients with enteritis, and children under 6 months are prohibited.
In the past, patients with a history of penicillin anaphylactic shock should use cefixime capsules with caution, because anaphylactic shock may also occur.
2. The serum half-life of patients with renal insufficiency is prolonged, and the dosage should be adjusted.
3. The dosage of the same suspension and tablet is higher than before.
The blood concentration is higher than the former.
4. The course of treatment of pyogenic streptococcus infection needs at least 10 days.
5. Patients with otitis media should be treated with suspension.
Neonates and premature infants should be cautious in using children's drugs.
Elderly patients should use drugs with caution.
The safety and effectiveness of cefixime capsules (Oujian) used by pregnant women and lactating women have not been established, and cefixime capsules (Oujian) are only used when really necessary; It is not clear whether cefixime capsules (Oujian) are secreted by milk, and breastfeeding should be suspended if necessary.
Drug Interaction Carbamazepine: When combined with cefixime capsules (Oujian), the level of carbamazepine can be improved, and the blood concentration of carbamazepine should be monitored when combined.
Warfarin and anticoagulant drugs: when combined with cefixime capsules (Oujian), prothrombin time increases.
Excessive gastric lavage, no special detoxification drugs, hemodialysis and peritoneal dialysis can not effectively remove cefixime capsules (Oujian).
Pharmacology, Toxicology and Pharmacology: Cefoxime Capsule (Oujian) is the third generation oral cephalosporin, with a wide antibacterial spectrum, and has antibacterial activity against some Gram-positive bacteria and negative bacteria, especially streptococcus (except enterococcus), pneumococcus, Neisseria gonorrhoeae, Brandenburg coccus, Escherichia coli, Serratia, Proteus and influenza virus. Its mechanism of action is to prevent the synthesis of bacterial cell wall, and the action point varies with the species of bacteria, and it has high affinity with PBP 1 (1A, 1B, 1C) and PBP3 in pbps (PBP).
Cefoxime capsule (Oujian) has strong stability to β -lactamases produced by various bacteria.
Toxicological study on reproductive toxicity: SD rats were given 100 ~ 1000 mg/kg orally before and at the beginning of pregnancy, and 320 ~ 3200 mg/kg orally during organogenesis, perinatal period and lactation period, which had no effect on the fertility of rats and no teratogenic effect, and the growth, development and reproductive ability of newborn mice were normal.
Pharmacokinetics according to PDR57, the absolute bioavailability of cefixime after oral administration is 40 ~ 50%, which is not affected by diet.
After a single oral dose of 200mg, the peak plasma concentration of cefixime tablets was 3.7μg/mL, and the peak plasma concentration of cefixime suspension was 25% ~ 50% higher than that of tablets.
The average peak concentrations of cefixime 200mg suspension and 400mg suspension were 3μg/mL and 4.6μg/mL, respectively, and the area under the time-concentration curve was 100mg ~ 400mg, which was 10%-25% higher than that of oral tablets with the same dose. When replacing tablet dosage form with suspension dosage form, the increase of absorption should be considered.
The peak time of 200mg tablets, 400mg tablets and 400mg suspensions is 2-6 hours, and that of 200mg suspensions is 2-5 hours.
Within 24 hours, 50% of the absorbed drugs are excreted from the urine in the original form.
The binding rate of serum protein was 65%, and cefixime did not accumulate in the body after continuous administration for 14 days.
The plasma half-life of cefixime is 3 ~ 4 hours, but it can reach 9 hours in some volunteers, regardless of the dosage form.
Pharmacokinetics of elderly patients in special population: the average AUCS at steady state is about 40% higher than that of normal adults.
Subjects with renal insufficiency: when the creatinine clearance rate is 20 ~ 50 ml/min, the average serum half-life of cefixime is extended to 6.4 hours; When the creatinine clearance rate was 5 ~ 20 ml/min, the average serum half-life of cefixime was prolonged to11.5h.
Hemodialysis and peritoneal dialysis: cefixime can not be effectively removed from the blood.
However, it has also been suggested that the blood changes of hemodialysis patients taking 400mg cefixime are similar to those of subjects with creatinine clearance level of 2 1-60mL/min.
Store in a dark place.
Packaging: Plastic-plastic blister packaging, each box 12 capsules.
Valid for 24 months.
Implement the standard YBH 17782004.
Approval number: National Medicine Zhunzi H2004 1669
Ou Yi younuokang pharmacy co., ltd
Efficacy and Function of Cefexoxime Capsule (Oujian) is used for pharyngitis, tonsillitis, acute bronchitis and acute attack of chronic bronchitis, otitis media, urinary tract infection and simple gonorrhea (cervicitis or urethritis) caused by sensitive bacteria.
Common problems in the use of cefixime capsules
The drug instruction may look like a useless piece of paper, but it is a guide to ensure the safety of our medication.
Everything in the drug instructions is too important to be ignored.
The precautions of drugs are to remind us of the details we should pay attention to when using drugs, so it is very important.
Cefexoxime capsule is one of the commonly used drugs in our daily life, which has a wide range of functions.
So, what are the precautions for cefixime capsules?
Precautions for cefixime capsules are as follows: 1. Due to the possibility of shock, medical history should be fully inquired before taking medicine.
2. In order to prevent the emergence of drug-resistant strains, the sensitivity should be confirmed in principle before using cefixime capsules, and the dose should be controlled at the minimum dose required for disease control.
3. For patients with severe renal dysfunction, because the drug can maintain the blood concentration, it should be appropriately reduced according to the renal function, and the dosing interval should be appropriately increased.
4. The following patients should use drugs with caution, (1) patients with allergic history of penicillin drugs; (2) I or my parents, brothers, patients with allergic symptoms such as bronchial asthma, rash and urticaria.
(3) Patients with severe renal insufficiency.
(4) Patients with oral or non-oral nutritional intake difficulties and patients with systemic cachexia (due to symptoms of vitamin K deficiency, attention should be paid to observation).
5. Influence on clinical test results: (1) If urine sugar is detected by Bancroft reagent, Fehling reagent and urine sugar test paper, it may be false positive, so pay attention.
(2) Attention should be paid to the possibility of false positive in direct comb test.
6. Don't mix milk, juice, etc. Put it away.
The dosage of cefixime capsules is 0. 1g( 1 capsule) for adults and children weighing over 30kg, twice a day; In addition, it can be appropriately increased or decreased according to age, weight and symptoms. For critically ill patients, 0.2g(2 capsules) each time, twice a day.
This concludes the introduction of the functions and efficacy of cefalexin capsules and cefalexin capsules. I wonder if you have found the information you need? If you want to know more about this, remember to collect this website.