Function: Tea clothes made of leaves and flowers can treat hypertension. Pharmacological action 1. Effects on cardiovascular and cerebrovascular systems: Single dose or multiple doses of hawthorn leaf flavonoids can antagonize acute myocardial ischemia induced by pituitrin in rabbits and narrow the range of myocardial infarction. Intravenous injection of hawthorn leaf extract (0. 1g/ml)0.4-8ml/kg can significantly reduce or restore the S-T segment deviation and T wave increase of ECG in guinea pigs caused by pituitrin, and accelerate the bradycardia caused by pituitrin. Vitex rhamnose 20ml/kg can obviously reduce the myocardial oxygen consumption of sitting heart in dogs, which has synergistic effect with hyperoside. The aqueous extract of hawthorn leaves can significantly reduce the serum creatine phosphokinase (CPK) level and myocardial infarction area in rats with coronary artery ligation. When 20% hawthorn extract was injected into the jugular vein for 5-7min, the cerebrovascular resistance decreased1.064-10.91KP/a (8-82 mmhg). 2. Effect on coagulation system Hawthorn leaves can significantly inhibit rabbit platelet aggregation induced by collagen or ADP in vitro and in vivo. In addition, after intravenous injection of hawthorn leaf preparation for 30 minutes, the specific viscosity of whole blood decreased significantly. 3. Hypolipidemic effect Hawthorn leaves have a very significant effect on cholesterolemia in mice rapidly formed by egg yolk milk. 4. Anti-hypoxia effect Hawthorn leaves, like propranolol, can significantly prolong the survival time of experimental mice under low pressure or normal pressure hypoxia, which is consistent with significantly reducing the overall oxygen consumption of mice. 5. Diuretic effect Hawthorn leaf extract has obvious diuretic effect. The urine volume of rabbits increased by 44.2% after 60min, 53.9% after 90min and 63.7% after 65,438+0.20 min, indicating that its diuretic effect is mild, slow and lasting, and Hawthorn leaves have little effect on electrolytes.