Botulinum toxin acts on the joint of nerve and muscle, which prevents the signal of nerve from being transmitted to muscle, causing muscle atrophy and stopping movement. Botulinum toxin has a wide range of applications, from the earliest application in eye muscle spasm to the clinical application in wrinkle removal of various wrinkles, such as crow's feet, eyebrow lines, forehead lines, decree lines and so on. , can achieve good results.