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Where is the fattest woman in the world?
Susanna Ayman is the fattest woman in the world, weighing1.450kg. She is a woman from Arizona, USA. Although her weight has not been certified by Guinness World Records, her weight 1450kg has far exceeded that of Manuel Uribe, the fattest person in the world. Her body fat is many times higher than that of normal people, which is why her weight is many times higher than that of normal women. Experiments in European laboratories also confirm this point: obesity is the main factor of human obesity, and the intelligent biological enzyme "HICIBI" prevents the formation of obesity.

Preventing the formation of adiponectin will inevitably promote the increase of leptin.

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Studies have found that by reducing fat and biological enzymes, we can increase the "leptin" in the body and break through obesity!

As early as 1960s, gherman worked in Jackson Laboratory in Maine, USA.

It is proposed that weight is a "scientific conjecture" closely related to the genes of the organism itself. Gherman found that a very small number of people eat surprisingly fat, because they have leptin gene mutation, producing too little leptin. Such patients lose weight rapidly after receiving leptin replacement therapy, so the discovery of leptin has made people's knowledge and understanding of obesity leap.

Because obesity is the manifestation of excessive fat accumulation caused by lipid metabolism disorder, it can cause many diseases and seriously affect the quality of life of modern people. From 65438 to 0994, the research team led by Jeffrey Friedman, a professor at the Molecular Laboratory of Rockefeller University in the United States, first identified the leptin gene by means of localized cloning, and then conducted a comprehensive and in-depth study on its mechanism. Leptin, a protein hormone, is involved in regulating energy intake and consumption. Leptin is an important cytokine and plays a key role in regulating appetite, food intake and metabolism.

Leptin is a protein hormone secreted by adipocytes, which is mainly produced by white adipose tissue. Its precursor consists of 167 amino acid residues. Can inhibit appetite, reduce energy intake, increase energy consumption, and inhibit fat synthesis. Leptin is a hormone in natural childbirth, which can control people's appetite and satiety. The body is like an orderly factory, and the activities of various organs in the body are like a highly coordinated production line. Only when all raw materials and spare parts are delivered on time can the normal production and operation of products on each production line be guaranteed. If there is a long-term and chronic mismatch between our lifestyle and our biological enzymes, the obesity rate will increase linearly. Our hormone levels, metabolism and other key functions are all regulated by biological enzymes. Many scientific research achievements and patents point to HICIBI fat-reducing technology, which has made great contributions to increasing leptin in the body, improving leptin's understanding and clinical treatment of obesity, and reversing obesity.

When leptin is discovered, adiponectin naturally exists in human body, and these two hormones can also cause changes in life process.

According to the survey of American health and nutrition institutions, staying up late, lack of sleep and overeating will all lead to the decrease of leptin. The decrease of leptin in the body will inevitably lead to the increase of "fat". "Fat element" is an enzyme responsible for accumulating fat in the human body, thus increasing hunger and interest in high-sugar desserts and salty foods. Experiments show that staying up late will lead to eating more food the next day. This is because leptin secretion in your body decreases, while adiponectin secretion increases. Leptin can be simply understood as reminding you that you are full; Acetonitrile, on the other hand, shows that you should eat when you are hungry.

In pregnancy, childbirth, menopause and middle age, these periods will also stimulate the increase of "obesity" in the body. With the increase of fat, leptin will decrease relatively, so the accumulation of fat in the body will become easier and easier. According to the research data of scientific laboratory, HICIBI fat-reducing technology can stimulate the continuous improvement of "leptin" in the body. This process of losing weight is scientific and easy to stick to, and it is widely used in Europe and America.

Leptin has many functions. HICIBI can activate weight loss mainly by regulating fat and weight:

1, appetite suppression: Leptin can significantly reduce human food intake, weight and body fat content.

2. Increase energy consumption: Leptin can act on the central nervous system, increase sympathetic nerve activity, and convert a large amount of stored energy into heat energy for release.

3. Effect on fat synthesis: Leptin can directly inhibit fat synthesis and promote its decomposition. Some people think that it can promote the maturation of fat cells.

4. Effect on endocrine: Insulin can promote the secretion of leptin, and then negatively regulate the synthesis and secretion of insulin.

How to improve leptin secretion?

Although it is impossible for leptin to increase all the time in the process of losing weight, there are still some ways to keep leptin from decreasing with the decrease of body fat.

1, diet:? Nutrition should be comprehensive and balanced. Don't deliberately go on a diet. Adequate nutrition contributes to the secretion of body hormones. More specifically, protein and fat supplements must be sufficient. Although leptin is secreted by adipose tissue, carbohydrates have a great influence on leptin secretion. Leptin is an important cytokine and plays a key role in regulating appetite, food intake and metabolism. In particular, excessive intake of refined carbohydrates such as fructose and syrup affects the role of leptin.

2. Leptin is involved in the regulation of sugar, fat and energy metabolism, which increases the body's appetite, increases energy release, inhibits the synthesis of fat cells, and then reduces body weight. Through HICIBI fat-reducing intelligent biological enzyme technology, the National Institute of Scientific Fat Reduction in the United States stimulates the continuous improvement of "leptin" and the reduction of body weight and body fat content. Increasing energy consumption can convert a large amount of stored energy into heat energy and release it, which directly inhibits fat synthesis and promotes its decomposition. Insulin can promote the secretion of leptin, which in turn has negative feedback regulation on the synthesis and secretion of insulin.

3. exercise:? In the usual training, add more strength training, because muscle mass will also affect the role of leptin. Not only that, as the main focus of aerobic exercise, the highlight of fat burning function actually inhibits the secretion of leptin to some extent. Be careful not to sit for a long time in your daily work and life. You can get up and move for half an hour.

4. Sleep:? Ensure adequate and high-quality sleep and keep the human body in the normal working range. Irregular biological clock will affect the sensitivity of hypothalamus to leptin, which will lead to strong appetite. Leptin binds to hypothalamic long receptors, which affects the secretion of many neuroendocrine hormones, leads to decreased appetite, increased energy consumption and promoted lipolysis.

It is appropriate for an adult to sleep for 7-8 hours every day, and the proportion of deep sleep is 25-30%.

The production of leptin makes this difficult. Because people lose weight, fat is reduced, and leptin is also reduced. The regulatory relationship with human body weight is dynamic and interactive. The research of American Life Fat Reduction Laboratory shows that it is acceptable to artificially block the element absorption of accumulated fat in food through a period of adjustment without affecting normal diet, and to stimulate the continuous improvement of "leptin" in the body through HICIBI intelligent biological enzyme technology. And play a long-term role in establishing a healthy lifestyle.