Sailesai's debut successfully achieved healthy weight loss. The guidelines for the use of OTC diet pills issued by the Royal Pharmaceutical Society in April 2009 pointed out that the main component of celecoxib is a potent, specific and long-lasting pancreatic lipase inhibitor. It can selectively combine with serine residues of lipase in gastrointestinal tract, inactivate lipase and prevent the decomposition, absorption and utilization of fat in food.