Drug weight loss is an auxiliary means of obesity treatment-this is a common sense that obese friends must recognize, and it can also be called a cruel truth. Obese people should not take this as the main means, and generally only give medication when they are seriously obese. Theoretically, all kinds of diet pills have adverse reactions. Long-term use will cause people to rely on drugs and cause irreparable harm to the body. Drugs can not change the behavioral characteristics that lead to obesity, such as eating habits, exercise, work and rest habits, environmental factors, etc., so we should weigh the advantages and disadvantages when choosing drugs for treatment. 1. When using diet pills, the indications must be strictly controlled, and what medicine to use is best treated under the guidance of a specialist. Patients in any of the following situations should take diet pills: (1) First, you use the formula mentioned above to calculate your ideal weight (standard weight), and then compare it with your actual weight to see if you are really obese. Only people who weigh more than 20% of their normal weight can be considered truly obese. The reason why this point is emphasized is that the ideal weight in people's minds has been unrealistically lowered today when slim figure is popular again, and having a body like a fashion model has become the pursuit of many young women. Therefore, unless you are really obese, don't overeat, let alone take medicine to lose weight. Only moderately obese people, that is, people who are overweight by more than 30%, can be treated with diet and exercise at the same time. (2) Obese patients began to take effect after strict diet control and exercise therapy. However, due to various reasons, patients can't persist, resulting in weight rebound. At this time, it is wise to take some drugs with the treatment. (3) Some obese people with peptic ulcer have difficulty in diet control, so some drugs can be added. (4) Some people lose weight to some extent after diet control and physical exercise, but their weight rises again after half a year. You can take diet pills at this time. (5) Losers who lose weight by dieting can be treated with diet pills. 2. Selection of drugs Over the years, the funds spent on research and development of diet pills in the world have reached billions of dollars, and there are many kinds of diet pills on the market, especially more than 90 kinds of diet products officially sold in China. Faced with these endless weight-loss products, consumers are often dazzled and don't know how to like them, so they often "follow the advertisements". However, advertisements of some weight-loss products often exaggerate propaganda, mislead consumers, and even make consumers confused about the mechanism of weight-loss products that have been eaten for several months. It is worth mentioning that there are many factors to lose weight. What we need is the consumption of fat, not the loss of muscle and water. At present, there are many diet pills on the market that advertise how much weight can be lost in a week. Don't be superstitious about these advertisements. Some drugs may contain laxatives or diuretics, which may reduce your weight in a short time, but will lose water and electrolytes. You may feel dizzy, dry mouth and weak. Moreover, the "weight loss" effect of these drugs is not lasting. The choice of slimming drugs is very important to the effect and safety of slimming. Some appetite suppressants, such as fenfluramine, which is very popular abroad, have serious complications to the heart and have been banned in the United States at present. Therefore, when obese people lose weight, they must understand the ingredients and action principles of various drugs, and must be responsible for their own health and clearly consume those "mysterious" weight-loss products on the market. These drugs can be used when dietary restriction, exercise and behavioral therapy are still not completely effective. Appetite inhibitors can reduce hunger and lose weight quickly. In the comprehensive treatment, if the appetite suppressant with adjusted dose or maximum tolerance has been used for 3-4 weeks, the weight has not been significantly reduced, and the treatment of such drugs should be stopped; If you continue to lose weight, you can continue to use it for a while. 4. Duration of medication Some people argue that appetite suppressants can only be used for a short period of time when the diet control effect is not good, but others think that appetite suppressants can be used for a long time to maintain the weight loss effect and prevent weight gain. 5. Combination medication Most effective diet pills have different degrees of adverse reactions, especially when used in large doses. The combined application of drugs with different mechanisms of action can enhance the efficacy of weight loss, reduce the dosage of drugs and reduce the incidence of adverse reactions. For example, fenfluramine, an appetite suppressant, is mixed with phenylbutylamine. Because of its different mechanisms on foraging behavior, the former enhances the 5- hydroxytryptamine system, while the latter enhances the catecholamine effect to produce appetite suppression. When the two drugs are used together, the dosage of each drug is reduced, but the appetite suppression effect is enhanced, and the weight loss effect is no less than either of them, and the adverse reactions are reduced. Long-term use of earthworm can lead to hyperinsulinemia, so the curative effect of long-term use is reduced. If insulin sensitizers such as troglitazone and metformin are used together, the adverse reactions of earthworm can be corrected and the curative effect can be enhanced. The combination of traditional Chinese medicine diet pills and low-dose appetite suppressants, such as Dahuang tablets and low-dose fenfluramine 10-20mg/ day, can reduce the incidence of adverse reactions and achieve good weight loss effect. 6. Adolescents who take drugs for special groups are in the growth and development stage, so it is necessary to conduct strict screening for weight loss treatment before taking drugs, and strict drug monitoring is necessary. Some studies believe that fenfluramine, earthworm, growth hormone and low dose thyroid hormone generally do not affect the growth and development of obese children. It is forbidden to use appetite suppressants during pregnancy and lactation, and other weight-loss drugs are not recommended, because they may affect fetal development and baby growth. Obese people with heart disease, hypertension or fatty liver must be careful when choosing diet pills. 7. Adverse reactions and drug selection must understand that all drugs have certain side effects, so don't take them blindly. It is best to see a doctor first and take it under the guidance of a doctor. This is safer and more effective. In order to avoid adverse reactions, we should generally take medicine from a small dose and gradually increase the dose to guide us to find a suitable dose that can effectively lose weight without obvious side effects. Most appetite suppressants and diet pills that increase energy consumption can produce different degrees of central nervous system excitement, which is manifested as irritable symptoms, insomnia, euphoria and so on. Susceptible population and long-term drug use will produce dependence and lead to abuse. Addicts who suddenly stop taking drugs will have withdrawal symptoms, especially amphetamine, so they can't lose weight with amphetamine and compound preparations containing amphetamine. Other amphetamine appetite suppressants, such as methamphetamine, are also prone to dependence and should only be used as second-line drugs to lose weight. The main adverse reaction of fenfluramine is sedation, which can cause depression, and high dose can cause excitement. After long-term medication, sudden withdrawal can cause severe depression, so this product can not be given intermittently. Appetite inhibitors, central stimulants and thyroid hormones that increase energy consumption can stimulate the sympathetic nervous system to produce dry mouth, dilated pupils, blurred vision, dizziness, tachycardia, elevated blood pressure and arrhythmia. Sweating, so it is not suitable for patients with hypertension, angina pectoris and hyperthyroidism. When earthworm and fenfluramine are used together, the incidence of the above adverse reactions is low. Generally speaking, when patients use the above-mentioned diet pills to lose weight, their blood pressure may drop, while susceptible people may have elevated blood pressure and tachycardia. There are many gastrointestinal reactions such as abdominal distension and excessive exhaust. When lipase inhibitors and glucose oxidase inhibitors are used. The former can also affect the absorption of fat-soluble vitamins, so long-term application should be cautious. 8. Drug Interaction Theoretically, most appetite suppressants can raise blood pressure and affect the effect of antihypertensive drugs. However, the interference of common appetite suppressants on the action of common antihypertensive drugs has no obvious clinical significance. However, in the first 4-6 weeks of treatment, blood pressure should be monitored every week. The combination of appetite suppressants and monoamine oxidase inhibitors can lead to hypertensive crisis, so patients who have used any monoamine oxidase inhibitors within 2 weeks should ban appetite suppressants.

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