How long can I lose weight by taking metformin?
1, how long can I lose weight by taking metformin?
Metformin can increase the anaerobic metabolism of glucose in muscle and reduce the energy supply of glucose to muscle tissue, so many patients with type 2 diabetes lose weight after taking the medicine. However, it should be noted that the main cause of obesity is the accumulation of adipose tissue in the body, which leads to weight gain. Metformin cannot solve the problem of fat accumulation.
Moreover, in practical application, if you want to lose weight obviously, you must take metformin in large doses, which often highlights the side effects of the drug. Most drug addicts will have digestive tract reactions, such as diarrhea, nausea, vomiting, abdominal distension, bad breath and so on. Long-term use is also easy to cause lactic acid accumulation, which may lead to lactic acid poisoning, nausea, vomiting, chest tightness and shortness of breath. In addition, it may also affect the absorption of water-soluble vitamins such as vitamin B 12 and folic acid, resulting in anemia, capillary and peripheral nerve damage, and also have a certain impact on the absorption of trace elements calcium and phosphorus.
From this point of view, it is obviously inappropriate for healthy people to take metformin as a weight loss health care drug. Again, "just exercise more, eat some coarse fiber foods and vegetables selectively, and keep your weight." Perseverance can still have a healthy "devil figure".
2. Can metformin be eaten for a long time?
We do not recommend taking metformin hydrochloride tablets for a long time. Long-term use will cause certain damage to liver and kidney function, and the digestive system will also have certain influence. Long-term use will also produce drug resistance effect, even if the dose is equivalent, the expected curative effect will not be achieved, and the body's sensitivity to drugs will be reduced, so long-term use is not recommended.
3. How to avoid the adverse reaction of taking metformin?
At the initial stage of taking metformin, especially when taking it on an empty stomach, about 10% ~ 20% of patients will have gastrointestinal discomfort, including nausea, vomiting, loss of appetite, metallic smell in the mouth, thin stool, diarrhea, etc. This is due to the high concentration of metformin hydrochloride immediately adhering to the gastrointestinal mucosa after the common dosage form of metformin is dissolved in the stomach. These adverse reactions are generally a one-time * * * lasting about 3 ~ 10 days * * *, which can be tolerated by ordinary people, and can be relieved by continuous medication.
Side effects of metformin tablets
1, gastrointestinal side effects: gastrointestinal side effects are the most common side effects of taking metformin hydrochloride. Everyone may have diarrhea, nausea, vomiting, abdominal distension, fatigue, indigestion, abdominal discomfort and so on. When metformin hydrochloride is used. These are all gastrointestinal side effects.
2. Lactic acidosis: This kind of acidosis is relatively rare, with a low incidence rate but a high mortality rate. Most of these side effects occur in patients with hypoxic diseases such as severe liver and renal insufficiency or cardiopulmonary insufficiency, so everyone should know more about their physical condition and use them with caution in patients with liver, kidney and cardiopulmonary diseases.
3. Hypoglycemia: The occurrence of hypoglycemia caused by metformin hydrochloride is relatively rare. However, when you eat too little or supplement insufficient calories after a large amount of exercise, you will have hypoglycemia when you use it with other hypoglycemic drugs such as sulfonylureas and insulin, and when you drink alcohol. You should pay attention to diet control and exercise rules. I used to eat less because of my bad appetite. Results After taking metformin, you feel dizzy and sweaty, so you should pay attention to diet and physical exercise during taking the medicine.
4. Others: allergic reaction, frequent urination, etc. After stopping the drug, it can be relieved or returned to normal. People who are allergic to metformin hydrochloride should not use this product.
Misunderstanding of metformin in losing weight
1, metformin can be used to lose weight.
Metformin can lose weight. However, obesity is a very complicated disease, involving multiple systems in the whole body, which requires multidisciplinary cooperation to formulate more professional and standardized treatment programs. At present, there is no evidence that metformin can be used to lose weight, whether it is the indication of metformin or the treatment scheme of obesity. Therefore, fat friends who want to lose weight with metformin must be cautious.
2, metformin will hurt the kidney.
Metformin hardly binds to plasma protein, and it can reach a stable blood concentration within 24~48 hours by oral administration according to the commonly used clinical dosage and administration scheme, mainly excreted by the kidney, and 90% can be excreted by the kidney within 24 hours. The kidney is only an organ that excretes metformin, and metformin itself will not have any adverse effects on the kidney. However, when metformin is used to reduce renal insufficiency, it may cause metformin accumulation, thus increasing the risk of lactic acidosis.
3, insulin can not take metformin.
One of the causes of type 2 diabetes is insulin resistance, and metformin can increase insulin sensitivity. Not only can you lose weight directly, but you can also indirectly reduce weight gain by reducing insulin dosage. Even in the treatment of 1 diabetes, metformin can be used in combination with insulin. Therefore, when using metformin to lose weight, we must pay attention to metformin as the "golden companion" of insulin.
4. Take metformin half an hour before meals.
The hypoglycemic drugs taken half an hour before meals mainly include sulfonylureas. However, metformin is mainly absorbed in the small intestine, and the absorption speed and degree of the drug are slightly reduced when taken with food. Therefore, metformin can be taken before meals to lose weight, but in order to avoid causing digestive tract reactions and affecting appetite, it can be taken immediately after meals or meals. People who have seen it also:
1. How long can I lose weight by taking metformin?
2. What are the misunderstandings of metformin in weight loss?