(1) laxative effect:
Function: Generally, loose stool will be discharged 6 ~ 10 hour after taking the medicine. Picture of rhubarb
Picture of rhubarb
Effective component of diarrhea: it is considered that the main component is sennoside.
Mechanism of catharsis: Sennoside decomposes under the action of intestinal bacterial enzymes to produce rhein anthrone, which can stimulate large intestinal mucosa, increase intestinal peristalsis and cause diarrhea. In addition, it can inhibit Na+ and K+-ATPase on intestinal cell membrane, hinder Na+ transport, increase intestinal osmotic pressure, retain a lot of water, and promote intestinal peristalsis and diarrhea.
(2) cholagogic and liver protection
(3) promoting the secretion of pancreatic juice and inhibiting the activity of pancreatic enzyme.
(4) Anti-gastric and duodenal ulcer
Effect on blood system
(1) Hemostatic effect:
Features: exact effect, quick effect.
Effective components for hemostasis: α-catechin and gallic acid.
Hemostasis mechanism: promoting platelet adhesion and aggregation function; Increase the number of platelets and the content of rhubarb in fibrinogen; Reduce antithrombin ⅲ activity; Vascular contraction at the injured site
(2) Reducing blood fat:
Reduce total cholesterol, triglyceride, low density lipoprotein, very low density lipoprotein and lipid peroxide.
Anti-infection effect
(1) pathogenic microorganisms:
Antibacterial spectrum:
Sensitive bacteria include staphylococcus, hemolytic streptococcus, Neisseria gonorrhoeae, diphtheria, typhoid fever and dysentery.
Sensitive viruses include influenza virus, orphan virus, hepatitis B virus and polio virus.
Other sensitive microorganisms include amoeba, trichomonas vaginalis, Schistosoma japonicum and leptospira.
Antibacterial active ingredients: rhein, emodin, aloe-emodin
Antibacterial mechanism: enzyme system affects folic acid; Inhibit the synthesis of bacterial nucleic acid and protein; Inhibition of bacterial biological oxidation enzyme system; Induced interferon.
(2) Anti-inflammatory and antipyretic effects
(3) Immunoregulation: Anthraquinone derivatives can inhibit nonspecific immune function.