The incidence of Raynaud's syndrome caused by secondary diseases is often higher than that of primary diseases, and it is more common in other diseases, such as systemic scleroderma, systemic lupus erythematosus, Sjogren's syndrome, polymyositis and dermatomyositis. , mainly connective tissue diseases, severe cases may be accompanied by fingertip ulcer, fingertip subcutaneous adipose tissue disappearance, fingertip disappearance, slow growth and thinning of nails, and even fingertip necrosis.
Extended data
The pathogenesis of Raynaud's phenomenon is not clear, which may be related to vascular endothelial factor, vascular nerve regulation, inflammatory state and other factors. The disease can be seen at any age, but it is more common in 20-40 years old, with more women than men. The onset is generally slow, and it is easy to occur in autumn and winter.
The typical attack of Reynolds phenomenon can be divided into three stages:
① Ischemic stage: refers to the early stage, which is easy to occur in the skin of the distal fingers and toes, presenting paroxysmal pallor, stiffness and coldness, accompanied by sweating, numbness or pain, and develops symmetrically from the tip of the fingers to the palm of the hand, but rarely exceeds the wrist;
(2) Hypoxia period: the affected area is continuously ischemic, the capillaries dilate and stagnate, the skin is cyanotic and purple, and the skin temperature is low and painful. At this time, the symptoms are generally mild;
③ Congestion period: Generally, it appears automatically when keeping warm. The duration of individual cases exceeded 1 hour. The above attacks often start from one finger and gradually appear similar symptoms in other fingers.
Baidu Encyclopedia-Renault Phenomenon