360, Alipay, asusvibedata, download and ksdownloads can all be moved to other disks. In addition, the Intel Directory may be an unzipped installer. Open it and you'll know this. If it is an installer, it can be deleted.

The focus is on the directory of windows and program files. You have to weigh this yourself, uninstall or delete unnecessary things.

In addition, if you want to slim down the system disk, you'd better cancel hibernation, run -cmd-powercfg -h off and then restart to delete Hiberfil.sys in the root directory of disk C, which will give you at least a few G's.