You know that these things are not necessarily reliable, and there is no national standard health care product/drug label on the product. Careful consideration of his theory can actually find a bunch of bugs, and asking him more questions can find countless problems that he can't explain. But you won't do it, and you still want to try.
No one wants to lose hope, which is why you are willing to play dumb and deceive yourself in front of weight loss products. However, it may also be because you don't know how unreliable it is.
Unlike many products on the market that don't know the principle, the advent of real diet pills will definitely be a story of the ages.
In the United States, any new drug must undergo rigorous clinical trials and pass the rigorous review of the US Food and Drug Administration before it can enter the market. The whole clinical trial process usually takes several years and costs hundreds of millions to billions of dollars.
The premise of these is that this drug has been developed, and the research and development process is another story with a long history.
Before scientists begin to develop diet pills, we should first pay enough attention to obesity and prove that obesity is a disease. Otherwise, how can we use precious scientific research funds and resources to study an irrelevant problem?
However, is obesity a serious social public health problem? It is still the personal habits and self-discipline of fat people, which has been debated for a long time. In 2000, the US Food and Drug Administration admitted that obesity is a disease, which means that pharmaceutical companies can develop and sell drugs and medical devices for obesity in the US market.
How to define obesity as a disease from the perspective of personal responsibility? Is there any evidence that obesity is not just a personal choice?
Because in the long evolutionary history, human ancestors lived a life of eating the last meal without the next. Those who managed to get a little food without filling themselves with energy are simply fools, and they don't know when the next time will come when they are hungry and cold.
Our genes have been constantly exercised and strengthened in this long evolutionary history. Eat, eat! It is human nature to eat whenever there is food. Everyone is born to "eat food", and restraint is against nature.
Yes, first of all, obesity is a disease, and then we will discuss ways to treat it. It was not without slimming products before. Even if obesity is not defined as a disease, most women still hate it. If those beauty and health care products aimed at losing weight were effective, why did obesity go to the position of disease?
If you want to treat obesity, you must first find out what is wrong with your body, otherwise there is no treatment at all. This is not a "conditioned reflex" to cope with the past.
In 1960s, scientists came to the conclusion through a series of animal experiments that there are two genes in mice, one of which will produce appetite suppressant (leptin), thus releasing a signal: "You have eaten too much, don't eat any more!" Another gene is responsible for receiving this information (leptin receptor) and making it reach the brain.
However, it took the scientists who made this bold guess for more than ten years to figure out what leptin really is. It was not until 1994 that another research group discovered leptin after eight years of exploration, and the scientists of Millennium Pharmaceutical Company also discovered leptin receptor.
1February, 996, Amgen announced that the recombinant leptin protein had officially started human trials. 1999 10 months, the clinical trial results show that although leptin can make obese people lose weight in a short time, it will also rebound quickly, and leptin has no effect on reducing and preventing obesity.
It can be said that the whole world was disappointed, and Amgen shares plummeted. Later, the road of leptin to lose weight was slowly blocked.
1938, two American doctors found that amphetamines can effectively reduce the weight of the subjects. Without this discovery, amphetamine as a drug can only be "hidden in the snow".
Amphetamines, also known as ephedrine. At first, it was used to relieve nasal congestion and asthma, and then slowly began to do magic. Sleepy people use it to stay awake, depressed people use it to improve their mood, and drivers who burn the midnight oil use it to keep their attention. ...
Do you think this taste is very wrong? There is no such magic medicine in the world. If there is, it should be a drug. Well-known methamphetamine is a violent version of amphetamine.
However, because amphetamine can lose weight, scientists try their best to change this chemical, keep its weight-losing part and remove its addictive part.
Then came the castrated version of amphetamine, Fen Flaaming. Although there is no addiction and the effect is not satisfactory, there are many annoying side effects, so this diet drug is not selling well.
1992, a professor at the University of Rochester found that Fenfen Flaaming and another weight-loss drug, Fentamine, were very effective, so he developed a combination of the two drugs-Fenfen. Fenfen is popular all over the United States because of its good weight loss effect.
But now the story is over. 1997, the myth of Fenfen came to an end and Fen Fleming was forced to withdraw from the market. Because, during the period of 1996- 1997, hundreds of vermicelli users suffered from fatal cardiovascular diseases, which was a very heavy price to pay for losing weight in history.
After these storms and black history, the US Food and Drug Administration has become very cautious. Chlorcasselin is the first slimming drug approved for marketing after 1998. It is used for obese (body mass index ≥ 30kg/m2) and overweight (body mass index ≥ 27kg/m2) patients with weight-related risk factors (such as hypertension, dyslipidemia or type 2 diabetes).
Another relatively mild and effective weight-loss drug is orlistat, which works by reducing the absorption of fat in the small intestine, but the excess fat will be discharged with the stool. You may not know what it feels like to have greasy stool, which is said to lead to spots on underwear.
It can be said that every drug is a very tortuous process from research and development to approval of clinical trials, to completion of clinical trials and to successful listing, in which scientific support is extremely difficult. And these are not "diet pills" that you can buy casually.
The diet pills you can buy can only be health care products at most, but in most cases, the identity and origin are unknown, and the mechanism of action is unclear. Because it is not so easy to get a batch number of health care products, and weight loss health care products are the most difficult among health care products.
It took scientists more than half a century to solve the problem of human obesity. Why do you believe that those "diet pills" that have not been clinically verified can help you lose weight?
If they are really effective and have no side effects, the global medical system should thank them and use them to solve urgent disease problems first, not beauty problems.