Anti-aging should be early, because with the increase of age, the DNA repair ability in the body will decline, leading to an increase in damage accumulation, which will lead to cell aging. Sirtuins (mainly SIRT 1, SIRT4 and SIRT6) participate in DNA damage reaction and repair, and play a vital role in maintaining the integrity of the genome, so they have become important anti-aging targets. In addition, after the age of 20, skin collagen will be lost at the rate of 1% per year. Therefore, the sooner you start anti-aging, the better!